BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

194 related articles for article (PubMed ID: 20010939)

  • 21. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase.
    Sakurikar N; Thompson R; Montano R; Eastman A
    Oncotarget; 2016 Jan; 7(2):1380-94. PubMed ID: 26595527
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1.
    Casagrande F; Darbon JM
    Biochem Pharmacol; 2001 May; 61(10):1205-15. PubMed ID: 11322924
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Resistance to cyclin-dependent kinase (CDK) 4/6 inhibitors confers cross-resistance to other CDK inhibitors but not to chemotherapeutic agents in breast cancer cells.
    Ogata R; Kishino E; Saitoh W; Koike Y; Kurebayashi J
    Breast Cancer; 2021 Jan; 28(1):206-215. PubMed ID: 32860163
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells.
    Doisneau-Sixou SF; Sergio CM; Carroll JS; Hui R; Musgrove EA; Sutherland RL
    Endocr Relat Cancer; 2003 Jun; 10(2):179-86. PubMed ID: 12790780
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Sensitivity of breast cancer cells to erlotinib depends on cyclin-dependent kinase 2 activity.
    Yamasaki F; Zhang D; Bartholomeusz C; Sudo T; Hortobagyi GN; Kurisu K; Ueno NT
    Mol Cancer Ther; 2007 Aug; 6(8):2168-77. PubMed ID: 17671085
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differences in the Conformational Energy Landscape of CDK1 and CDK2 Suggest a Mechanism for Achieving Selective CDK Inhibition.
    Wood DJ; Korolchuk S; Tatum NJ; Wang LZ; Endicott JA; Noble MEM; Martin MP
    Cell Chem Biol; 2019 Jan; 26(1):121-130.e5. PubMed ID: 30472117
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Phosphorylation of mixed lineage kinase MLK3 by cyclin-dependent kinases CDK1 and CDK2 controls ovarian cancer cell division.
    Cedeno-Rosario L; Honda D; Sunderland AM; Lewandowski MD; Taylor WR; Chadee DN
    J Biol Chem; 2022 Aug; 298(8):102263. PubMed ID: 35843311
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
    Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
    [TBL] [Abstract][Full Text] [Related]  

  • 29. KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer.
    Anbalagan M; Carrier L; Glodowski S; Hangauer D; Shan B; Rowan BG
    Breast Cancer Res Treat; 2012 Apr; 132(2):391-409. PubMed ID: 21509526
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibitors of Cyclin-Dependent Kinase 1/2 for Anticancer Treatment.
    Mou J; Chen D; Deng Y
    Med Chem; 2020; 16(3):307-325. PubMed ID: 31241436
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Nuclear targeting of cyclin-dependent kinase 2 reveals essential roles of cyclin-dependent kinase 2 localization and cyclin E in vitamin D-mediated growth inhibition.
    Flores O; Wang Z; Knudsen KE; Burnstein KL
    Endocrinology; 2010 Mar; 151(3):896-908. PubMed ID: 20147522
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Anti-HER2 antibody trastuzumab inhibits CDK2-mediated NPAT and histone H4 expression via the PI3K pathway.
    Le XF; Bedrosian I; Mao W; Murray M; Lu Z; Keyomarsi K; Lee MH; Zhao J; Bast RC
    Cell Cycle; 2006 Aug; 5(15):1654-61. PubMed ID: 16861913
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 6,7,4'-trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2.
    Lee DE; Lee KW; Jung SK; Lee EJ; Hwang JA; Lim TG; Kim BY; Bode AM; Lee HJ; Dong Z
    Carcinogenesis; 2011 Apr; 32(4):629-35. PubMed ID: 21258042
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Down-regulation of p21WAF1/CIP1 or p27Kip1 abrogates antiestrogen-mediated cell cycle arrest in human breast cancer cells.
    Cariou S; Donovan JC; Flanagan WM; Milic A; Bhattacharya N; Slingerland JM
    Proc Natl Acad Sci U S A; 2000 Aug; 97(16):9042-6. PubMed ID: 10908655
    [TBL] [Abstract][Full Text] [Related]  

  • 35. BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype.
    Marconett CN; Morgenstern TJ; San Roman AK; Sundar SN; Singhal AK; Firestone GL
    Cancer Biol Ther; 2010 Aug; 10(4):397-405. PubMed ID: 20574166
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells.
    Patel P; Tsiperson V; Gottesman SRS; Somma J; Blain SW
    Mol Cancer Res; 2018 Mar; 16(3):361-377. PubMed ID: 29330290
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.
    Deep G; Singh RP; Agarwal C; Kroll DJ; Agarwal R
    Oncogene; 2006 Feb; 25(7):1053-69. PubMed ID: 16205633
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A pure estrogen antagonist inhibits cyclin E-Cdk2 activity in MCF-7 breast cancer cells and induces accumulation of p130-E2F4 complexes characteristic of quiescence.
    Carroll JS; Prall OW; Musgrove EA; Sutherland RL
    J Biol Chem; 2000 Dec; 275(49):38221-9. PubMed ID: 10991938
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Removal of Cdk inhibitors through both sequestration and downregulation in zearalenone-treated MCF-7 breast cancer cells.
    Ahamed S; Foster JS; Bukovsky A; Diehl JA; Wimalasena J
    Mol Carcinog; 2002 May; 34(1):45-58. PubMed ID: 12112322
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Estrogen receptor coregulator binding modulator (ERX-11) enhances the activity of CDK4/6 inhibitors against estrogen receptor-positive breast cancers.
    Viswanadhapalli S; Ma S; Sareddy GR; Lee TK; Li M; Gilbreath C; Liu X; Luo Y; Pratap UP; Zhou M; Blatt EB; Kassees K; Arteaga C; Alluri P; Rao M; Weintraub ST; Tekmal RR; Ahn JM; Raj GV; Vadlamudi RK
    Breast Cancer Res; 2019 Dec; 21(1):150. PubMed ID: 31878959
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.