BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 20012574)

  • 1. Coming full circle: cyclin-dependent kinases as anti-cancer drug targets.
    Fisher RP
    Subcell Biochem; 2010; 50():1-15. PubMed ID: 20012574
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Progress in the evaluation of CDK inhibitors as anti-tumor agents.
    McInnes C
    Drug Discov Today; 2008 Oct; 13(19-20):875-81. PubMed ID: 18639646
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ATP-noncompetitive inhibitors of CDK-cyclin complexes.
    Orzáez M; Gortat A; Mondragón L; Bachs O; Pérez-Payá E
    ChemMedChem; 2009 Jan; 4(1):19-24. PubMed ID: 19039815
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cyclins and related kinases in cancer cells.
    Malumbres M
    J BUON; 2007 Sep; 12 Suppl 1():S45-52. PubMed ID: 17935277
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol.
    Knockaert M; Lenormand P; Gray N; Schultz P; Pouysségur J; Meijer L
    Oncogene; 2002 Sep; 21(42):6413-24. PubMed ID: 12226745
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Recent advances and new directions in the discovery and development of cyclin-dependent kinase inhibitors.
    Fischer PM
    Curr Opin Drug Discov Devel; 2001 Sep; 4(5):623-34. PubMed ID: 12825457
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of potent pyrazolo[4,3-h]quinazoline-3-carboxamides as multi-cyclin-dependent kinase inhibitors.
    Traquandi G; Ciomei M; Ballinari D; Casale E; Colombo N; Croci V; Fiorentini F; Isacchi A; Longo A; Mercurio C; Panzeri A; Pastori W; Pevarello P; Volpi D; Roussel P; Vulpetti A; Brasca MG
    J Med Chem; 2010 Mar; 53(5):2171-87. PubMed ID: 20141146
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SNS-032 is a potent and selective CDK 2, 7 and 9 inhibitor that drives target modulation in patient samples.
    Conroy A; Stockett DE; Walker D; Arkin MR; Hoch U; Fox JA; Hawtin RE
    Cancer Chemother Pharmacol; 2009 Sep; 64(4):723-32. PubMed ID: 19169685
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cyclin-dependent kinase and protein kinase C inhibitors: a novel class of antineoplastic agents in clinical development.
    Kaubisch A; Schwartz GK
    Cancer J; 2000; 6(4):192-212. PubMed ID: 11038138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15.
    Iavarone A; Massagué J
    Nature; 1997 May; 387(6631):417-22. PubMed ID: 9163429
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Anticancer activity and differentially expressed genes in head and neck cancer cells treated with a novel cyclin-dependent kinase inhibitor.
    Shin HC; Song DW; Baek WK; Lee SR; Kwon TK; Lee J; Park SH; Jang BC; Park JW
    Chemotherapy; 2009; 55(5):353-62. PubMed ID: 19657189
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The roles and therapeutic potential of cyclin-dependent kinases (CDKs) in sarcoma.
    Liao Y; Feng Y; Shen J; Hornicek FJ; Duan Z
    Cancer Metastasis Rev; 2016 Jun; 35(2):151-63. PubMed ID: 26669603
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting Cyclin-Dependent Kinases and Cell Cycle Progression in Human Cancers.
    Santo L; Siu KT; Raje N
    Semin Oncol; 2015 Dec; 42(6):788-800. PubMed ID: 26615126
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cyclin-dependent kinases: bridging their structure and function through computations.
    De Vivo M; Bottegoni G; Berteotti A; Recanatini M; Gervasio FL; Cavalli A
    Future Med Chem; 2011 Sep; 3(12):1551-9. PubMed ID: 21882947
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Investigational drugs targeting cyclin-dependent kinases for the treatment of cancer: an update on recent findings (2013-2016).
    Di Giovanni C; Novellino E; Chilin A; Lavecchia A; Marzaro G
    Expert Opin Investig Drugs; 2016 Oct; 25(10):1215-30. PubMed ID: 27606939
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Small Molecule CDK Inhibitors for the Therapeutic Management of Cancer.
    Goel B; Tripathi N; Bhardwaj N; Jain SK
    Curr Top Med Chem; 2020; 20(17):1535-1563. PubMed ID: 32416692
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dissecting the Pol II transcription cycle and derailing cancer with CDK inhibitors.
    Parua PK; Fisher RP
    Nat Chem Biol; 2020 Jul; 16(7):716-724. PubMed ID: 32572259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potential Clinical Uses of CDK Inhibitors: Lessons from Synthetic Lethality Screens.
    Vymětalová L; Kryštof V
    Med Res Rev; 2015 Nov; 35(6):1156-74. PubMed ID: 26114963
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibitors of cyclin-dependent kinases as cancer therapeutics.
    Whittaker SR; Mallinger A; Workman P; Clarke PA
    Pharmacol Ther; 2017 May; 173():83-105. PubMed ID: 28174091
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cell cycle, CDKs and cancer: a changing paradigm.
    Malumbres M; Barbacid M
    Nat Rev Cancer; 2009 Mar; 9(3):153-66. PubMed ID: 19238148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.