These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 20018214)

  • 21. Computational analysis of the evolution of 1-deoxy-D-xylulose-5-phosphate Reductoisomerase, an important enzyme in plant terpene biosynthesis.
    Fung PK; Krushkal J; Weathers PJ
    Chem Biodivers; 2010 May; 7(5):1098-110. PubMed ID: 20491066
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity.
    Wiesner J; Ortmann R; Jomaa H; Schlitzer M
    Arch Pharm (Weinheim); 2007 Dec; 340(12):667-9. PubMed ID: 17994601
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cloning and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase gene for diterpenoid tanshinone biosynthesis in Salvia miltiorrhiza (Chinese sage) hairy roots.
    Wu SJ; Shi M; Wu JY
    Biotechnol Appl Biochem; 2009 Jan; 52(Pt 1):89-95. PubMed ID: 18302535
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
    Devreux V; Wiesner J; Jomaa H; Van der Eycken J; Van Calenbergh S
    Bioorg Med Chem Lett; 2007 Sep; 17(17):4920-3. PubMed ID: 17583502
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Isolation of the dxr gene of Zymomonas mobilis and characterization of the 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
    Grolle S; Bringer-Meyer S; Sahm H
    FEMS Microbiol Lett; 2000 Oct; 191(1):131-7. PubMed ID: 11004410
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum.
    Umeda T; Tanaka N; Kusakabe Y; Nakanishi M; Kitade Y; Nakamura KT
    Sci Rep; 2011; 1():9. PubMed ID: 22355528
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A sugar phosphatase regulates the methylerythritol phosphate (MEP) pathway in malaria parasites.
    Guggisberg AM; Park J; Edwards RL; Kelly ML; Hodge DM; Tolia NH; Odom AR
    Nat Commun; 2014 Jul; 5():4467. PubMed ID: 25058848
    [TBL] [Abstract][Full Text] [Related]  

  • 28. [Cloning and analysis of cDNA encoding key enzyme gene (dxr) of the non-MVA pathway in Taxus chinensis cells].
    Zheng QP; Yu LJ; Liu Z; Li MY; Xiang F; Yang Q
    Sheng Wu Gong Cheng Xue Bao; 2004 Jul; 20(4):548-53. PubMed ID: 15968987
    [TBL] [Abstract][Full Text] [Related]  

  • 29. In silico identification of promiscuous scaffolds as potential inhibitors of 1-deoxy-d-xylulose 5-phosphate reductoisomerase for treatment of Falciparum malaria.
    Wadood A; Ghufran M; Hassan SF; Khan H; Azam SS; Rashid U
    Pharm Biol; 2017 Dec; 55(1):19-32. PubMed ID: 27650666
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The malarial drug target Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (PfDXR): development of a 3-D model for identification of novel, structural and functional features and for inhibitor screening.
    Goble JL; Adendorff MR; de Beer TA; Stephens LL; Blatch GL
    Protein Pept Lett; 2010 Jan; 17(1):109-20. PubMed ID: 20214634
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Enhanced flux through the methylerythritol 4-phosphate pathway in Arabidopsis plants overexpressing deoxyxylulose 5-phosphate reductoisomerase.
    Carretero-Paulet L; Cairó A; Botella-Pavía P; Besumbes O; Campos N; Boronat A; Rodríguez-Concepción M
    Plant Mol Biol; 2006 Nov; 62(4-5):683-95. PubMed ID: 16941216
    [TBL] [Abstract][Full Text] [Related]  

  • 32. MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.
    Edwards RL; Brothers RC; Wang X; Maron MI; Ziniel PD; Tsang PS; Kraft TE; Hruz PW; Williamson KC; Dowd CS; John ARO
    Sci Rep; 2017 Aug; 7(1):8400. PubMed ID: 28827774
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Molecular cloning, expression profiling and functional analysis of a DXR gene encoding 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Camptotheca acuminata.
    Yao H; Gong Y; Zuo K; Ling H; Qiu C; Zhang F; Wang Y; Pi Y; Liu X; Sun X; Tang K
    J Plant Physiol; 2008 Feb; 165(2):203-13. PubMed ID: 17257708
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Comparative protein modeling of 1-deoxy-D-xylulose-5-phosphate reductoisomerase enzyme from Plasmodium falciparum: a potential target for antimalarial drug discovery.
    Singh N; Chevé G; Avery MA; McCurdy CR
    J Chem Inf Model; 2006; 46(3):1360-70. PubMed ID: 16711755
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues.
    Ortmann R; Wiesner J; Silber K; Klebe G; Jomaa H; Schlitzer M
    Arch Pharm (Weinheim); 2007 Sep; 340(9):483-90. PubMed ID: 17806130
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Cloning and heterologous expression of a cDNA encoding 1-deoxy-D-xylulose-5-phosphate reductoisomerase of Arabidopsis thaliana.
    Schwender J; Müller C; Zeidler J; Lichtenthaler HK
    FEBS Lett; 1999 Jul; 455(1-2):140-4. PubMed ID: 10428488
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
    Giessmann D; Heidler P; Haemers T; Van Calenbergh S; Reichenberg A; Jomaa H; Weidemeyer C; Sanderbrand S; Wiesner J; Link A
    Chem Biodivers; 2008 Apr; 5(4):643-56. PubMed ID: 18421757
    [TBL] [Abstract][Full Text] [Related]  

  • 38. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
    Proteau PJ
    Bioorg Chem; 2004 Dec; 32(6):483-93. PubMed ID: 15530989
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthetic Fosmidomycin analogues with altered chelating moieties do not inhibit 1-deoxy-d-xylulose 5-phosphate Reductoisomerase or Plasmodium falciparum growth in vitro.
    Chofor R; Risseeuw MD; Pouyez J; Johny C; Wouters J; Dowd CS; Couch RD; Van Calenbergh S
    Molecules; 2014 Feb; 19(2):2571-87. PubMed ID: 24566322
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Structure-guided design and biosynthesis of a novel FR-900098 analogue as a potent Plasmodium falciparum 1-deoxy-D-xylulose-5-phosphate reductoisomerase (Dxr) inhibitor.
    Cobb RE; Bae B; Li Z; DeSieno MA; Nair SK; Zhao H
    Chem Commun (Camb); 2015 Feb; 51(13):2526-8. PubMed ID: 25567100
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.