These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

709 related articles for article (PubMed ID: 20022946)

  • 1. mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action.
    Soliman GA; Acosta-Jaquez HA; Dunlop EA; Ekim B; Maj NE; Tee AR; Fingar DC
    J Biol Chem; 2010 Mar; 285(11):7866-79. PubMed ID: 20022946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
    Acosta-Jaquez HA; Keller JA; Foster KG; Ekim B; Soliman GA; Feener EP; Ballif BA; Fingar DC
    Mol Cell Biol; 2009 Aug; 29(15):4308-24. PubMed ID: 19487463
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2.
    Feldman ME; Apsel B; Uotila A; Loewith R; Knight ZA; Ruggero D; Shokat KM
    PLoS Biol; 2009 Feb; 7(2):e38. PubMed ID: 19209957
    [TBL] [Abstract][Full Text] [Related]  

  • 4. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1).
    García-Martínez JM; Alessi DR
    Biochem J; 2008 Dec; 416(3):375-85. PubMed ID: 18925875
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition.
    Damerill I; Biggar KK; Abu Shehab M; Li SS; Jansson T; Gupta MB
    Mol Endocrinol; 2016 Feb; 30(2):201-16. PubMed ID: 26714229
    [TBL] [Abstract][Full Text] [Related]  

  • 6. mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling.
    Julien LA; Carriere A; Moreau J; Roux PP
    Mol Cell Biol; 2010 Feb; 30(4):908-21. PubMed ID: 19995915
    [TBL] [Abstract][Full Text] [Related]  

  • 7. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Distinct signaling mechanisms of mTORC1 and mTORC2 in glioblastoma multiforme: a tale of two complexes.
    Jhanwar-Uniyal M; Gillick JL; Neil J; Tobias M; Thwing ZE; Murali R
    Adv Biol Regul; 2015 Jan; 57():64-74. PubMed ID: 25442674
    [TBL] [Abstract][Full Text] [Related]  

  • 9. TORC-specific phosphorylation of mammalian target of rapamycin (mTOR): phospho-Ser2481 is a marker for intact mTOR signaling complex 2.
    Copp J; Manning G; Hunter T
    Cancer Res; 2009 Mar; 69(5):1821-7. PubMed ID: 19244117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting mTOR globally in cancer: thinking beyond rapamycin.
    Shor B; Gibbons JJ; Abraham RT; Yu K
    Cell Cycle; 2009 Dec; 8(23):3831-7. PubMed ID: 19901542
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
    Chen CH; Kiyan V; Zhylkibayev AA; Kazyken D; Bulgakova O; Page KE; Bersimbaev RI; Spooner E; Sarbassov DD
    J Biol Chem; 2013 Sep; 288(38):27019-27030. PubMed ID: 23928304
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
    Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
    J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
    [TBL] [Abstract][Full Text] [Related]  

  • 13. LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.
    Shaw RJ
    Acta Physiol (Oxf); 2009 May; 196(1):65-80. PubMed ID: 19245654
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Regulation of proline-rich Akt substrate of 40 kDa (PRAS40) function by mammalian target of rapamycin complex 1 (mTORC1)-mediated phosphorylation.
    Wang L; Harris TE; Lawrence JC
    J Biol Chem; 2008 Jun; 283(23):15619-27. PubMed ID: 18372248
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N; Karsy M; Albert L; Murali R; Jhanwar-Uniyal M
    Int J Oncol; 2009 Oct; 35(4):731-40. PubMed ID: 19724909
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1.
    Thoreen CC; Kang SA; Chang JW; Liu Q; Zhang J; Gao Y; Reichling LJ; Sim T; Sabatini DM; Gray NS
    J Biol Chem; 2009 Mar; 284(12):8023-32. PubMed ID: 19150980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A.
    Harwood FC; Shu L; Houghton PJ
    J Biol Chem; 2008 Feb; 283(5):2575-85. PubMed ID: 18056704
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity.
    Liu L; Luo Y; Chen L; Shen T; Xu B; Chen W; Zhou H; Han X; Huang S
    J Biol Chem; 2010 Dec; 285(49):38362-73. PubMed ID: 20937815
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rapamycin-resistant mTORC1 kinase activity is required for herpesvirus replication.
    Moorman NJ; Shenk T
    J Virol; 2010 May; 84(10):5260-9. PubMed ID: 20181700
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.
    Luo Y; Liu L; Wu Y; Singh K; Su B; Zhang N; Liu X; Shen Y; Huang S
    Oncotarget; 2015 Feb; 6(6):4286-98. PubMed ID: 25738366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.