308 related articles for article (PubMed ID: 20027226)
1. Dihydro-CDDO-trifluoroethyl amide (dh404), a novel Nrf2 activator, suppresses oxidative stress in cardiomyocytes.
Ichikawa T; Li J; Meyer CJ; Janicki JS; Hannink M; Cui T
PLoS One; 2009 Dec; 4(12):e8391. PubMed ID: 20027226
[TBL] [Abstract][Full Text] [Related]
2. Triterpenoid dihydro-CDDO-trifluoroethyl amide protects against maladaptive cardiac remodeling and dysfunction in mice: a critical role of Nrf2.
Xing Y; Niu T; Wang W; Li J; Li S; Janicki JS; Ruiz S; Meyer CJ; Wang XL; Tang D; Zhao Y; Cui T
PLoS One; 2012; 7(9):e44899. PubMed ID: 23028668
[TBL] [Abstract][Full Text] [Related]
3. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores endothelial function impaired by reduced Nrf2 activity in chronic kidney disease.
Aminzadeh MA; Reisman SA; Vaziri ND; Shelkovnikov S; Farzaneh SH; Khazaeli M; Meyer CJ
Redox Biol; 2013; 1(1):527-31. PubMed ID: 24363993
[TBL] [Abstract][Full Text] [Related]
4. Dihydro-CDDO-trifluoroethyl amide suppresses inflammatory responses in macrophages via activation of Nrf2.
Li B; Abdalrahman A; Lai Y; Janicki JS; Ward KW; Meyer CJ; Wang XL; Tang D; Cui T
Biochem Biophys Res Commun; 2014 Feb; 444(4):555-61. PubMed ID: 24486487
[TBL] [Abstract][Full Text] [Related]
5. The effect of Nrf2 pathway activation on human pancreatic islet cells.
Masuda Y; Vaziri ND; Li S; Le A; Hajighasemi-Ossareh M; Robles L; Foster CE; Stamos MJ; Al-Abodullah I; Ricordi C; Ichii H
PLoS One; 2015; 10(6):e0131012. PubMed ID: 26110640
[TBL] [Abstract][Full Text] [Related]
6. Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.
Kaspar JW; Niture SK; Jaiswal AK
J Cell Sci; 2012 Feb; 125(Pt 4):1027-38. PubMed ID: 22448038
[TBL] [Abstract][Full Text] [Related]
7. The NRF2 activator DH404 attenuates adverse ventricular remodeling post-myocardial infarction by modifying redox signalling.
Bubb KJ; Kok C; Tang O; Rasko NB; Birgisdottir AB; Hansen T; Ritchie R; Bhindi R; Reisman SA; Meyer C; Ward K; Karimi Galougahi K; Figtree GA
Free Radic Biol Med; 2017 Jul; 108():585-594. PubMed ID: 28438659
[TBL] [Abstract][Full Text] [Related]
8. The synthetic triterpenoid RTA dh404 (CDDO-dhTFEA) restores Nrf2 activity and attenuates oxidative stress, inflammation, and fibrosis in rats with chronic kidney disease.
Aminzadeh MA; Reisman SA; Vaziri ND; Khazaeli M; Yuan J; Meyer CJ
Xenobiotica; 2014 Jun; 44(6):570-8. PubMed ID: 24195589
[TBL] [Abstract][Full Text] [Related]
9. Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.
Zhang DD; Lo SC; Cross JV; Templeton DJ; Hannink M
Mol Cell Biol; 2004 Dec; 24(24):10941-53. PubMed ID: 15572695
[TBL] [Abstract][Full Text] [Related]
10. Diffusion dynamics of the Keap1-Cullin3 interaction in single live cells.
Baird L; Dinkova-Kostova AT
Biochem Biophys Res Commun; 2013 Mar; 433(1):58-65. PubMed ID: 23454126
[TBL] [Abstract][Full Text] [Related]
11. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2.
Kobayashi A; Kang MI; Okawa H; Ohtsuji M; Zenke Y; Chiba T; Igarashi K; Yamamoto M
Mol Cell Biol; 2004 Aug; 24(16):7130-9. PubMed ID: 15282312
[TBL] [Abstract][Full Text] [Related]
12. A potent Nrf2 activator, dh404, bolsters antioxidant capacity in glial cells and attenuates ischaemic retinopathy.
Deliyanti D; Lee JY; Petratos S; Meyer CJ; Ward KW; Wilkinson-Berka JL; de Haan JB
Clin Sci (Lond); 2016 Aug; 130(15):1375-87. PubMed ID: 27005782
[TBL] [Abstract][Full Text] [Related]
13. BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase.
Furukawa M; Xiong Y
Mol Cell Biol; 2005 Jan; 25(1):162-71. PubMed ID: 15601839
[TBL] [Abstract][Full Text] [Related]
14. Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.
Martinez VD; Vucic EA; Pikor LA; Thu KL; Hubaux R; Lam WL
Mol Cancer; 2013 Oct; 12(1):124. PubMed ID: 24138990
[TBL] [Abstract][Full Text] [Related]
15. The Keap1-BTB protein is an adaptor that bridges Nrf2 to a Cul3-based E3 ligase: oxidative stress sensing by a Cul3-Keap1 ligase.
Cullinan SB; Gordan JD; Jin J; Harper JW; Diehl JA
Mol Cell Biol; 2004 Oct; 24(19):8477-86. PubMed ID: 15367669
[TBL] [Abstract][Full Text] [Related]
16. Synthetic Triterpenoid RTA dh404 (CDDO-dhTFEA) Ameliorates Acute Pancreatitis.
Robles L; Vaziri ND; Li S; Masuda Y; Takasu C; Takasu M; Vo K; Farzaneh SH; Stamos MJ; Ichii H
Pancreas; 2016; 45(5):720-9. PubMed ID: 26495793
[TBL] [Abstract][Full Text] [Related]
17. Prothymosin-alpha mediates nuclear import of the INrf2/Cul3 Rbx1 complex to degrade nuclear Nrf2.
Niture SK; Jaiswal AK
J Biol Chem; 2009 May; 284(20):13856-13868. PubMed ID: 19279002
[TBL] [Abstract][Full Text] [Related]
18. Structure of the BTB domain of Keap1 and its interaction with the triterpenoid antagonist CDDO.
Cleasby A; Yon J; Day PJ; Richardson C; Tickle IJ; Williams PA; Callahan JF; Carr R; Concha N; Kerns JK; Qi H; Sweitzer T; Ward P; Davies TG
PLoS One; 2014; 9(6):e98896. PubMed ID: 24896564
[TBL] [Abstract][Full Text] [Related]
19. Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1.
Eggler AL; Small E; Hannink M; Mesecar AD
Biochem J; 2009 Jul; 422(1):171-80. PubMed ID: 19489739
[TBL] [Abstract][Full Text] [Related]
20. Unique pattern of component gene disruption in the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in serous ovarian cancer.
Martinez VD; Vucic EA; Thu KL; Pikor LA; Hubaux R; Lam WL
Biomed Res Int; 2014; 2014():159459. PubMed ID: 25114896
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]