These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 20035615)

  • 1. High-throughput multiplex flow cytometry screening for botulinum neurotoxin type a light chain protease inhibitors.
    Saunders MJ; Graves SW; Sklar LA; Oprea TI; Edwards BS
    Assay Drug Dev Technol; 2010 Feb; 8(1):37-46. PubMed ID: 20035615
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A high-throughput screening approach to anthrax lethal factor inhibition.
    Johnson SL; Chen LH; Pellecchia M
    Bioorg Chem; 2007 Aug; 35(4):306-12. PubMed ID: 17320146
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A high-throughput-compatible FRET-based platform for identification and characterization of botulinum neurotoxin light chain modulators.
    Caglič D; Bompiani KM; Krutein MC; Čapek P; Dickerson TJ
    J Vis Exp; 2013 Dec; (82):50908. PubMed ID: 24430674
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Saunders MJ; Edwards BS; Zhu J; Sklar LA; Graves SW
    Curr Protoc Cytom; 2010 Oct; Chapter 13():Unit 13.12.1-17. PubMed ID: 20938917
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The identification and biochemical characterization of drug-like compounds that inhibit botulinum neurotoxin serotype A endopeptidase activity.
    Cai S; Lindo P; Park JB; Vasa K; Singh BR
    Toxicon; 2010 Apr; 55(4):818-26. PubMed ID: 20003913
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthetic substrate for application in both high and low throughput assays for botulinum neurotoxin B protease inhibitors.
    Salzameda NT; Barbieri JT; Janda KD
    Bioorg Med Chem Lett; 2009 Oct; 19(20):5848-50. PubMed ID: 19747823
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
    Jacobson AR; Adler M; Silvaggi NR; Allen KN; Smith GM; Fredenburg RA; Stein RL; Park JB; Feng X; Shoemaker CB; Deshpande SS; Goodnough MC; Malizio CJ; Johnson EA; Pellett S; Tepp WH; Tzipori S
    Toxicon; 2017 Oct; 137():36-47. PubMed ID: 28698055
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Microsphere-based protease assays and screening application for lethal factor and factor Xa.
    Saunders MJ; Kim H; Woods TA; Nolan JP; Sklar LA; Edwards BS; Graves SW
    Cytometry A; 2006 May; 69(5):342-52. PubMed ID: 16604538
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel small molecule inhibitors of botulinum neurotoxin A metalloprotease activity.
    Burnett JC; Schmidt JJ; Stafford RG; Panchal RG; Nguyen TL; Hermone AR; Vennerstrom JL; McGrath CF; Lane DJ; Sausville EA; Zaharevitz DW; Gussio R; Bavari S
    Biochem Biophys Res Commun; 2003 Oct; 310(1):84-93. PubMed ID: 14511652
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Natural Compounds and Their Analogues as Potent Antidotes against the Most Poisonous Bacterial Toxin.
    Patel KB; Cai S; Adler M; Singh BK; Parmar VS; Singh BR
    Appl Environ Microbiol; 2018 Dec; 84(24):. PubMed ID: 30389764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of exosite-targeting inhibitors of anthrax lethal factor by high-throughput screening.
    Bannwarth L; Goldberg AB; Chen C; Turk BE
    Chem Biol; 2012 Jul; 19(7):875-82. PubMed ID: 22840775
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.
    Thenin-Houssier S; de Vera IM; Pedro-Rosa L; Brady A; Richard A; Konnick B; Opp S; Buffone C; Fuhrmann J; Kota S; Billack B; Pietka-Ottlik M; Tellinghuisen T; Choe H; Spicer T; Scampavia L; Diaz-Griffero F; Kojetin DJ; Valente ST
    Antimicrob Agents Chemother; 2016 Apr; 60(4):2195-208. PubMed ID: 26810656
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay.
    Surviladze Z; Waller A; Wu Y; Romero E; Edwards BS; Wandinger-Ness A; Sklar LA
    J Biomol Screen; 2010 Jan; 15(1):10-20. PubMed ID: 20008126
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of substrates and inhibitors of botulinum neurotoxin type A metalloprotease.
    Sukonpan C; Oost T; Goodnough M; Tepp W; Johnson EA; Rich DH
    J Pept Res; 2004 Feb; 63(2):181-93. PubMed ID: 15009541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Virtual medicinal chemistry: in silico pre-docking functional group transformation for discovery of novel inhibitors of botulinum toxin serotype A light chain.
    O'Malley S; Sareth S; Jiao GS; Kim S; Thai A; Cregar-Hernandez L; McKasson L; Margosiak SA; Johnson AT
    Bioorg Med Chem Lett; 2013 May; 23(9):2505-11. PubMed ID: 23545109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of botulinum neurotoxin a protease inhibitors.
    Li B; Pai R; Cardinale SC; Butler MM; Peet NP; Moir DT; Bavari S; Bowlin TL
    J Med Chem; 2010 Mar; 53(5):2264-76. PubMed ID: 20155918
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain.
    Seki H; Pellett S; Silhár P; Stowe GN; Blanco B; Lardy MA; Johnson EA; Janda KD
    Bioorg Med Chem; 2014 Feb; 22(3):1208-17. PubMed ID: 24360826
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Recent developments with metalloprotease inhibitor class of drug candidates for botulinum neurotoxins.
    Kumar G; Swaminathan S
    Curr Top Med Chem; 2015; 15(7):685-95. PubMed ID: 25751268
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Picolinic acids as β-exosite inhibitors of botulinum neurotoxin A light chain.
    Bremer PT; Xue S; Janda KD
    Chem Commun (Camb); 2016 Oct; 52(84):12521-12524. PubMed ID: 27722252
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of ebselen and its analogues as potent covalent inhibitors of papain-like protease from SARS-CoV-2.
    Weglarz-Tomczak E; Tomczak JM; Talma M; Burda-Grabowska M; Giurg M; Brul S
    Sci Rep; 2021 Feb; 11(1):3640. PubMed ID: 33574416
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.