These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 20039633)

  • 1. Matrix metalloproteinase 2 (MMP2) inhibition: DFT and QM/MM studies of the deprotonation-initialized ring-opening reaction of the sulfoxide analogue of SB-3CT.
    Tao P; Fisher JF; Shi Q; Mobashery S; Schlegel HB
    J Phys Chem B; 2010 Jan; 114(2):1030-7. PubMed ID: 20039633
    [TBL] [Abstract][Full Text] [Related]  

  • 2. QM/MM Studies of the Matrix Metalloproteinase 2 (MMP2) Inhibition Mechanism of (S)-SB-3CT and its Oxirane Analogue.
    Zhou J; Tao P; Fisher JF; Shi Q; Mobashery S; Schlegel HB
    J Chem Theory Comput; 2010 Nov; 6(11):3580-3587. PubMed ID: 21076643
    [TBL] [Abstract][Full Text] [Related]  

  • 3. DFT studies of the ring-opening mechanism of SB-3CT, a potent inhibitor of matrix metalloproteinase 2.
    Tao P; Fisher JF; Mobashery S; Schlegel HB
    Org Lett; 2009 Jun; 11(12):2559-62. PubMed ID: 19445474
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Matrix metalloproteinase 2 inhibition: combined quantum mechanics and molecular mechanics studies of the inhibition mechanism of (4-phenoxyphenylsulfonyl)methylthiirane and its oxirane analogue.
    Tao P; Fisher JF; Shi Q; Vreven T; Mobashery S; Schlegel HB
    Biochemistry; 2009 Oct; 48(41):9839-47. PubMed ID: 19754151
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Active site ring-opening of a thiirane moiety and picomolar inhibition of gelatinases.
    Forbes C; Shi Q; Fisher JF; Lee M; Hesek D; Llarrull LI; Toth M; Gossing M; Fridman R; Mobashery S
    Chem Biol Drug Des; 2009 Dec; 74(6):527-34. PubMed ID: 19807733
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Small-molecule MMP2/MMP9 inhibitor SB-3CT modulates tumor immune surveillance by regulating PD-L1.
    Ye Y; Kuang X; Xie Z; Liang L; Zhang Z; Zhang Y; Ma F; Gao Q; Chang R; Lee HH; Zhao S; Su J; Li H; Peng J; Chen H; Yin M; Peng C; Yang N; Wang J; Liu J; Liu H; Han L; Chen X
    Genome Med; 2020 Sep; 12(1):83. PubMed ID: 32988398
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.
    Solomon A; Rosenblum G; Gonzales PE; Leonard JD; Mobashery S; Milla ME; Sagi I
    J Biol Chem; 2004 Jul; 279(30):31646-54. PubMed ID: 15102849
    [TBL] [Abstract][Full Text] [Related]  

  • 8. X-ray absorption studies of human matrix metalloproteinase-2 (MMP-2) bound to a highly selective mechanism-based inhibitor. comparison with the latent and active forms of the enzyme.
    Kleifeld O; Kotra LP; Gervasi DC; Brown S; Bernardo MM; Fridman R; Mobashery S; Sagi I
    J Biol Chem; 2001 May; 276(20):17125-31. PubMed ID: 11278946
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational analyses of thiirane-based gelatinase inhibitors.
    Lee M; Hesek D; Shi Q; Noll BC; Fisher JF; Chang M; Mobashery S
    Bioorg Med Chem Lett; 2008 May; 18(10):3064-7. PubMed ID: 18083555
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Matrix metalloproteinases 2 and 9 are elevated in human preterm laboring uterine myometrium and exacerbate uterine contractility†.
    Ulrich CC; Arinze V; Wandscheer CB; Copley Salem C; Nabati C; Etezadi-Amoli N; Burkin HR
    Biol Reprod; 2019 Jun; 100(6):1597-1604. PubMed ID: 30951583
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, kinetic characterization and metabolism of diastereomeric 2-(1-(4-phenoxyphenylsulfonyl)ethyl)thiiranes as potent gelatinase and MT1-MMP inhibitors.
    Gooyit M; Lee M; Hesek D; Boggess B; Oliver AG; Fridman R; Mobashery S; Chang M
    Chem Biol Drug Des; 2009 Dec; 74(6):535-46. PubMed ID: 19824893
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MMP-9 inhibitor SB-3CT attenuates behavioral impairments and hippocampal loss after traumatic brain injury in rat.
    Jia F; Yin YH; Gao GY; Wang Y; Cen L; Jiang JY
    J Neurotrauma; 2014 Jul; 31(13):1225-34. PubMed ID: 24661104
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective inhibition of matrix metalloproteinase-9 attenuates secondary damage resulting from severe traumatic brain injury.
    Hadass O; Tomlinson BN; Gooyit M; Chen S; Purdy JJ; Walker JM; Zhang C; Giritharan AB; Purnell W; Robinson CR; Shin D; Schroeder VA; Suckow MA; Simonyi A; Sun GY; Mobashery S; Cui J; Chang M; Gu Z
    PLoS One; 2013; 8(10):e76904. PubMed ID: 24194849
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective gelatinase inhibitor neuroprotective agents cross the blood-brain barrier.
    Gooyit M; Suckow MA; Schroeder VA; Wolter WR; Mobashery S; Chang M
    ACS Chem Neurosci; 2012 Oct; 3(10):730-6. PubMed ID: 23077716
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Testosterone-induced matrix metalloproteinase activation is a checkpoint for neuronal addition to the adult songbird brain.
    Kim DH; Lilliehook C; Roides B; Chen Z; Chang M; Mobashery S; Goldman SA
    J Neurosci; 2008 Jan; 28(1):208-16. PubMed ID: 18171938
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibition of MMP-9 by a selective gelatinase inhibitor protects neurovasculature from embolic focal cerebral ischemia.
    Cui J; Chen S; Zhang C; Meng F; Wu W; Hu R; Hadass O; Lehmidi T; Blair GJ; Lee M; Chang M; Mobashery S; Sun GY; Gu Z
    Mol Neurodegener; 2012 May; 7():21. PubMed ID: 22587708
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of Matrix Metalloproteinase 9 Enhances Rod Survival in the S334ter-line3 Retinitis Pigmentosa Model.
    Shin JA; Kim HS; Vargas A; Yu WQ; Eom YS; Craft CM; Lee EJ
    PLoS One; 2016; 11(11):e0167102. PubMed ID: 27893855
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Blockade of MMP-2 and MMP-9 inhibits corneal lymphangiogenesis.
    Du HT; Du LL; Tang XL; Ge HY; Liu P
    Graefes Arch Clin Exp Ophthalmol; 2017 Aug; 255(8):1573-1579. PubMed ID: 28669039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury.
    Lee M; Chen Z; Tomlinson BN; Gooyit M; Hesek D; Juárez MR; Nizam R; Boggess B; Lastochkin E; Schroeder VA; Wolter WR; Suckow MA; Cui J; Mobashery S; Gu Z; Chang M
    ACS Chem Neurosci; 2015 Oct; 6(10):1658-64. PubMed ID: 26241578
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of MMP-9 activity following hypoxic ischemia in the developing brain using a highly specific inhibitor.
    Ranasinghe HS; Scheepens A; Sirimanne E; Mitchell MD; Williams CE; Fraser M
    Dev Neurosci; 2012; 34(5):417-27. PubMed ID: 23171520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.