BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 20040361)

  • 1. Activation of PPARdelta up-regulates fatty acid oxidation and energy uncoupling genes of mitochondria and reduces palmitate-induced apoptosis in pancreatic beta-cells.
    Wan J; Jiang L; Lü Q; Ke L; Li X; Tong N
    Biochem Biophys Res Commun; 2010 Jan; 391(3):1567-72. PubMed ID: 20040361
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells.
    Coll T; Alvarez-Guardia D; Barroso E; Gómez-Foix AM; Palomer X; Laguna JC; Vázquez-Carrera M
    Endocrinology; 2010 Apr; 151(4):1560-9. PubMed ID: 20185762
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of PPARδ promotes mitochondrial energy metabolism and decreases basal insulin secretion in palmitate-treated β-cells.
    Jiang L; Wan J; Ke LQ; Lü QG; Tong NW
    Mol Cell Biochem; 2010 Oct; 343(1-2):249-56. PubMed ID: 20571903
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PPARdelta is a fatty acid sensor that enhances mitochondrial oxidation in insulin-secreting cells and protects against fatty acid-induced dysfunction.
    Ravnskjaer K; Frigerio F; Boergesen M; Nielsen T; Maechler P; Mandrup S
    J Lipid Res; 2010 Jun; 51(6):1370-9. PubMed ID: 19965574
    [TBL] [Abstract][Full Text] [Related]  

  • 5. PPARδ activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
    Feng YZ; Nikolić N; Bakke SS; Boekschoten MV; Kersten S; Kase ET; Rustan AC; Thoresen GH
    Arch Physiol Biochem; 2014 Feb; 120(1):12-21. PubMed ID: 23991827
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Myocardial infarction in rats causes partial impairment in insulin response associated with reduced fatty acid oxidation and mitochondrial gene expression.
    Amorim PA; Nguyen TD; Shingu Y; Schwarzer M; Mohr FW; Schrepper A; Doenst T
    J Thorac Cardiovasc Surg; 2010 Nov; 140(5):1160-7. PubMed ID: 20850803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activation of PPARβ/δ protects pancreatic β cells from palmitate-induced apoptosis by upregulating the expression of GLP-1 receptor.
    Yang Y; Tong Y; Gong M; Lu Y; Wang C; Zhou M; Yang Q; Mao T; Tong N
    Cell Signal; 2014 Feb; 26(2):268-78. PubMed ID: 24269940
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential 3,5,3'-triiodothyronine-mediated regulation of uncoupling protein 3 transcription: role of Fatty acids.
    de Lange P; Feola A; Ragni M; Senese R; Moreno M; Lombardi A; Silvestri E; Amat R; Villarroya F; Goglia F; Lanni A
    Endocrinology; 2007 Aug; 148(8):4064-72. PubMed ID: 17478558
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Time-course effects of increased fatty acid supply on the expression of genes involved in lipid/glucose metabolism in muscle cells.
    Rodríguez AM; Sánchez J; Tobaruela A; Priego T; Picó C; Palou A
    Cell Physiol Biochem; 2010; 25(2-3):337-46. PubMed ID: 20110694
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The PPARδ Agonist GW501516 Improves Lipolytic/Lipogenic Balance through CPT1 and PEPCK during the Development of Pre-Implantation Bovine Embryos.
    Idrees M; Xu L; El Sheikh M; Sidrat T; Song SH; Joo MD; Lee KL; Kong IK
    Int J Mol Sci; 2019 Dec; 20(23):. PubMed ID: 31810173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Protective Role of PPARdelta in Lipoapoptosis of Pancreatic β Cells.
    Yang Y; Ren J; Tong Y; Hu X; Lv Q; Tong N
    Lipids; 2016 Nov; 51(11):1259-1268. PubMed ID: 27631677
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Regulation of energy metabolism by long-chain fatty acids.
    Nakamura MT; Yudell BE; Loor JJ
    Prog Lipid Res; 2014 Jan; 53():124-44. PubMed ID: 24362249
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Candesartan attenuates fatty acid-induced oxidative stress and NAD(P)H oxidase activity in pancreatic beta-cells.
    Saitoh Y; Hongwei W; Ueno H; Mizuta M; Nakazato M
    Diabetes Res Clin Pract; 2010 Oct; 90(1):54-9. PubMed ID: 20667613
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.
    Krämer DK; Al-Khalili L; Guigas B; Leng Y; Garcia-Roves PM; Krook A
    J Biol Chem; 2007 Jul; 282(27):19313-20. PubMed ID: 17500064
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The PPARdelta agonist, GW501516, promotes fatty acid oxidation but has no direct effect on glucose utilisation or insulin sensitivity in rat L6 skeletal muscle cells.
    Dimopoulos N; Watson M; Green C; Hundal HS
    FEBS Lett; 2007 Oct; 581(24):4743-8. PubMed ID: 17869249
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Peroxisome proliferator-activated receptor δ improves porcine blastocyst hatching via the regulation of fatty acid oxidation.
    Guo J; Lu WF; Liang S; Choi JW; Kim NH; Cui XS
    Theriogenology; 2017 Mar; 90():266-275. PubMed ID: 28166979
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Excess lipid availability increases mitochondrial fatty acid oxidative capacity in muscle: evidence against a role for reduced fatty acid oxidation in lipid-induced insulin resistance in rodents.
    Turner N; Bruce CR; Beale SM; Hoehn KL; So T; Rolph MS; Cooney GJ
    Diabetes; 2007 Aug; 56(8):2085-92. PubMed ID: 17519422
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation.
    Wallin T; Ma Z; Ogata H; Jørgensen IH; Iezzi M; Wang H; Wollheim CB; Björklund A
    Biochim Biophys Acta; 2010 Feb; 1801(2):191-7. PubMed ID: 19931418
    [TBL] [Abstract][Full Text] [Related]  

  • 19. H₂O₂-Activated Mitochondrial Phospholipase iPLA₂γ Prevents Lipotoxic Oxidative Stress in Synergy with UCP2, Amplifies Signaling via G-Protein-Coupled Receptor GPR40, and Regulates Insulin Secretion in Pancreatic β-Cells.
    Ježek J; Dlasková A; Zelenka J; Jabůrek M; Ježek P
    Antioxid Redox Signal; 2015 Oct; 23(12):958-72. PubMed ID: 25925080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Uncoupling protein-2 attenuates palmitoleate protection against the cytotoxic production of mitochondrial reactive oxygen species in INS-1E insulinoma cells.
    Barlow J; Hirschberg Jensen V; Affourtit C
    Redox Biol; 2015; 4():14-22. PubMed ID: 25482405
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.