BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

410 related articles for article (PubMed ID: 20042712)

  • 1. Activation of the cystic fibrosis transmembrane conductance regulator by the flavonoid quercetin: potential use as a biomarker of ΔF508 cystic fibrosis transmembrane conductance regulator rescue.
    Pyle LC; Fulton JC; Sloane PA; Backer K; Mazur M; Prasain J; Barnes S; Clancy JP; Rowe SM
    Am J Respir Cell Mol Biol; 2010 Nov; 43(5):607-16. PubMed ID: 20042712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DeltaF508 CFTR processing correction and activity in polarized airway and non-airway cell monolayers.
    Rowe SM; Pyle LC; Jurkevante A; Varga K; Collawn J; Sloane PA; Woodworth B; Mazur M; Fulton J; Fan L; Li Y; Fortenberry J; Sorscher EJ; Clancy JP
    Pulm Pharmacol Ther; 2010 Aug; 23(4):268-78. PubMed ID: 20226262
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deletion of phenylalanine 508 causes attenuated phosphorylation-dependent activation of CFTR chloride channels.
    Wang F; Zeltwanger S; Hu S; Hwang TC
    J Physiol; 2000 May; 524 Pt 3(Pt 3):637-48. PubMed ID: 10790148
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Failure of cAMP agonists to activate rescued deltaF508 CFTR in CFBE41o- airway epithelial monolayers.
    Bebok Z; Collawn JF; Wakefield J; Parker W; Li Y; Varga K; Sorscher EJ; Clancy JP
    J Physiol; 2005 Dec; 569(Pt 2):601-15. PubMed ID: 16210354
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel amino-carbonitrile-pyrazole identified in a small molecule screen activates wild-type and ΔF508 cystic fibrosis transmembrane conductance regulator in the absence of a cAMP agonist.
    Namkung W; Park J; Seo Y; Verkman AS
    Mol Pharmacol; 2013 Sep; 84(3):384-92. PubMed ID: 23788656
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A domain mimic increases DeltaF508 CFTR trafficking and restores cAMP-stimulated anion secretion in cystic fibrosis epithelia.
    Clarke LL; Gawenis LR; Hwang TC; Walker NM; Gruis DB; Price EM
    Am J Physiol Cell Physiol; 2004 Jul; 287(1):C192-9. PubMed ID: 15028554
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Quercetin increases cystic fibrosis transmembrane conductance regulator-mediated chloride transport and ciliary beat frequency: therapeutic implications for chronic rhinosinusitis.
    Zhang S; Smith N; Schuster D; Azbell C; Sorscher EJ; Rowe SM; Woodworth BA
    Am J Rhinol Allergy; 2011; 25(5):307-12. PubMed ID: 22186243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human-mouse cystic fibrosis transmembrane conductance regulator (CFTR) chimeras identify regions that partially rescue CFTR-ΔF508 processing and alter its gating defect.
    Dong Q; Ostedgaard LS; Rogers C; Vermeer DW; Zhang Y; Welsh MJ
    Proc Natl Acad Sci U S A; 2012 Jan; 109(3):917-22. PubMed ID: 22210114
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Endogenous surface expression of ΔF508-CFTR mediates cAMP-stimulated Cl(-) current in CFTR(ΔF508/ΔF508) pig thyroid epithelial cells.
    Li Y; Ganta S; Fong P
    Exp Physiol; 2012 Jan; 97(1):115-24. PubMed ID: 21948195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating.
    Xu LN; Na WL; Liu X; Hou SG; Lin S; Yang H; Ma TH
    Clin Exp Pharmacol Physiol; 2008 Aug; 35(8):878-83. PubMed ID: 18430055
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A truncated CFTR protein rescues endogenous DeltaF508-CFTR and corrects chloride transport in mice.
    Cormet-Boyaka E; Hong JS; Berdiev BK; Fortenberry JA; Rennolds J; Clancy JP; Benos DJ; Boyaka PN; Sorscher EJ
    FASEB J; 2009 Nov; 23(11):3743-51. PubMed ID: 19620404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Base treatment corrects defects due to misfolding of mutant cystic fibrosis transmembrane conductance regulator.
    Namkung W; Kim KH; Lee MG
    Gastroenterology; 2005 Dec; 129(6):1979-90. PubMed ID: 16344066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
    Swiatecka-Urban A; Brown A; Moreau-Marquis S; Renuka J; Coutermarsh B; Barnaby R; Karlson KH; Flotte TR; Fukuda M; Langford GM; Stanton BA
    J Biol Chem; 2005 Nov; 280(44):36762-72. PubMed ID: 16131493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Annexin A5 increases the cell surface expression and the chloride channel function of the DeltaF508-cystic fibrosis transmembrane regulator.
    Le Drévo MA; Benz N; Kerbiriou M; Giroux-Metges MA; Pennec JP; Trouvé P; Férec C
    Biochim Biophys Acta; 2008 Oct; 1782(10):605-14. PubMed ID: 18773956
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Targeting autophagy as a novel strategy for facilitating the therapeutic action of potentiators on ΔF508 cystic fibrosis transmembrane conductance regulator.
    Luciani A; Villella VR; Esposito S; Gavina M; Russo I; Silano M; Guido S; Pettoello-Mantovani M; Carnuccio R; Scholte B; De Matteis A; Maiuri MC; Raia V; Luini A; Kroemer G; Maiuri L
    Autophagy; 2012 Nov; 8(11):1657-72. PubMed ID: 22874563
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Rescue of DeltaF508-CFTR (cystic fibrosis transmembrane conductance regulator) by curcumin: involvement of the keratin 18 network.
    Lipecka J; Norez C; Bensalem N; Baudouin-Legros M; Planelles G; Becq F; Edelman A; Davezac N
    J Pharmacol Exp Ther; 2006 May; 317(2):500-5. PubMed ID: 16424149
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Resveratrol ameliorates abnormalities of fluid and electrolyte secretion in a hypoxia-Induced model of acquired CFTR deficiency.
    Woodworth BA
    Laryngoscope; 2015 Oct; 125 Suppl 7(0 7):S1-S13. PubMed ID: 25946147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SYVN1, NEDD8, and FBXO2 Proteins Regulate ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation.
    Ramachandran S; Osterhaus SR; Parekh KR; Jacobi AM; Behlke MA; McCray PB
    J Biol Chem; 2016 Dec; 291(49):25489-25504. PubMed ID: 27756846
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Modulation of deltaF508 cystic fibrosis transmembrane regulator trafficking and function with 4-phenylbutyrate and flavonoids.
    Lim M; McKenzie K; Floyd AD; Kwon E; Zeitlin PL
    Am J Respir Cell Mol Biol; 2004 Sep; 31(3):351-7. PubMed ID: 15191910
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of wild-type and deltaF508 cystic fibrosis transmembrane regulator in human respiratory epithelia.
    Kreda SM; Mall M; Mengos A; Rochelle L; Yankaskas J; Riordan JR; Boucher RC
    Mol Biol Cell; 2005 May; 16(5):2154-67. PubMed ID: 15716351
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.