BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 20043314)

  • 1. Phenyl-oxazoles, a new family of inverse agonists at the H(3) histamine receptor.
    Denonne F; Atienzar F; Célanire S; Christophe B; Delannois F; Delaunoy C; Delporte ML; Durieu V; Gillard M; Lallemand B; Lamberty Y; Lorent G; Vanbellinghen A; Van Houtvin N; Verbois V; Provins L
    ChemMedChem; 2010 Feb; 5(2):206-12. PubMed ID: 20043314
    [No Abstract]   [Full Text] [Related]  

  • 2. Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists.
    Célanire S; Wijtmans M; Christophe B; Collart P; de Esch I; Dassesse D; Delaunoy C; Denonne F; Durieu V; Gelens E; Gillard M; Lallemand B; Lamberty Y; Lebon F; Nicolas JM; Quéré L; Snip E; Vanbellinghen A; Van Houtvin N; Verbois V; Timmerman H; Talaga P; Leurs R; Provins L
    ChemMedChem; 2009 Jul; 4(7):1063-8. PubMed ID: 19405064
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel substituted pyrrolidines are high affinity histamine H3 receptor antagonists.
    Stocking EM; Aluisio L; Atack JR; Bonaventure P; Carruthers NI; Dugovic C; Everson A; Fraser I; Jiang X; Leung P; Lord B; Ly KS; Morton KL; Nepomuceno D; Shah CR; Shelton J; Soyode-Johnson A; Letavic MA
    Bioorg Med Chem Lett; 2010 May; 20(9):2755-60. PubMed ID: 20382018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. From an atypical wake-promoting agent to potent histamine-3 receptor inverse agonists.
    Dunn D; Raddatz R; Ator MA; Bacon ER; Chatterjee S
    Chem Biol Drug Des; 2013 Mar; 81(3):433-5. PubMed ID: 23205610
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design and evaluation of novel biphenyl sulfonamide derivatives with potent histamine H(3) receptor inverse agonist activity.
    Covel JA; Santora VJ; Smith JM; Hayashi R; Gallardo C; Weinhouse MI; Ibarra JB; Schultz JA; Park DM; Estrada SA; Hofilena BJ; Pulley MD; Smith BM; Ren A; Suarez M; Frazer J; Edwards J; Hauser EK; Lorea J; Semple G; Grottick AJ
    J Med Chem; 2009 Sep; 52(18):5603-11. PubMed ID: 19722526
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression.
    Gao Z; Hurst WJ; Czechtizky W; Hall D; Moindrot N; Nagorny R; Pichat P; Stefany D; Hendrix JA; George PG
    Bioorg Med Chem Lett; 2013 Dec; 23(23):6269-73. PubMed ID: 24139584
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ergoline-derived inverse agonists of the human h3 receptor for the treatment of narcolepsy.
    Auberson YP; Troxler T; Zhang X; Yang CR; Fendt M; Feuerbach D; Liu YC; Lagu B; Lerchner A; Perrone M; Lei L; Zhang C; Wang C; Wang TL; Bock MG
    ChemMedChem; 2014 Aug; 9(8):1683-96. PubMed ID: 24850792
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular modeling of histamine H3 receptor and QSAR studies on arylbenzofuran derived H3 antagonists.
    Dastmalchi S; Hamzeh-Mivehroud M; Ghafourian T; Hamzeiy H
    J Mol Graph Model; 2008 Jan; 26(5):834-44. PubMed ID: 17561422
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).
    Gao Z; Hurst WJ; Guillot E; Czechtizky W; Lukasczyk U; Nagorny R; Pruniaux MP; Schwink L; Sanchez JA; Stengelin S; Tang L; Winkler I; Hendrix JA; George PG
    Bioorg Med Chem Lett; 2013 Jun; 23(11):3421-6. PubMed ID: 23591112
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Non-imidazole histamine H3 ligands. Part III. New 4-n-propylpiperazines as non-imidazole histamine H3-antagonists.
    Walczyński K; Zuiderveld OP; Timmerman H
    Eur J Med Chem; 2005 Jan; 40(1):15-23. PubMed ID: 15642406
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, characterization, and biological assessment of the four stereoisomers of the H(3) receptor antagonist 5-fluoro-2-methyl-N-[2-methyl-4-(2-methyl[1,3']bipyrrolidinyl-1'-yl)phenyl]benzamide.
    Gao Z; Hurst WJ; Guillot E; Nagorny R; Pruniaux MP; Hendrix JA; George PG
    Bioorg Med Chem Lett; 2013 Jul; 23(14):4044-7. PubMed ID: 23769643
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new family of H3 receptor antagonists based on the natural product Conessine.
    Santora VJ; Covel JA; Hayashi R; Hofilena BJ; Ibarra JB; Pulley MD; Weinhouse MI; Sengupta D; Duffield JJ; Semple G; Webb RR; Sage C; Ren A; Pereira G; Knudsen J; Edwards JE; Suarez M; Frazer J; Thomsen W; Hauser E; Whelan K; Grottick AJ
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1490-4. PubMed ID: 18194865
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 3,4-Diaza-bicyclo[4.1.0]hept-4-en-2-one phenoxypropylamine analogs of irdabisant (CEP-26401) as potent histamine-3 receptor inverse agonists with robust wake-promoting activity.
    Hudkins RL; Becknell NC; Lyons JA; Aimone LD; Olsen M; Haltiwanger RC; Mathiasen JR; Raddatz R; Gruner JA
    Eur J Med Chem; 2015 May; 95():349-56. PubMed ID: 25827402
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, structure-activity relationships, and biological profiles of a quinazolinone class of histamine H3 receptor inverse agonists.
    Nagase T; Mizutani T; Ishikawa S; Sekino E; Sasaki T; Fujimura T; Ito S; Mitobe Y; Miyamoto Y; Yoshimoto R; Tanaka T; Ishihara A; Takenaga N; Tokita S; Fukami T; Sato N
    J Med Chem; 2008 Aug; 51(15):4780-9. PubMed ID: 18598020
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antiobesity evaluation of histamine H3 receptor (H3R) antagonist analogs of A-331440 with improved safety and efficacy.
    Hancock AA; Diehl MS; Fey TA; Bush EN; Faghih R; Miller TR; Krueger KM; Pratt JK; Cowart MD; Dickinson RW; Shapiro R; Knourek-Segel VE; Droz BA; McDowell CA; Krishna G; Brune ME; Esbenshade TA; Jacobson PB
    Inflamm Res; 2005 Apr; 54 Suppl 1():S27-9. PubMed ID: 15928821
    [No Abstract]   [Full Text] [Related]  

  • 16. Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.
    Hudkins RL; Raddatz R; Tao M; Mathiasen JR; Aimone LD; Becknell NC; Prouty CP; Knutsen LJ; Yazdanian M; Moachon G; Ator MA; Mallamo JP; Marino MJ; Bacon ER; Williams M
    J Med Chem; 2011 Jul; 54(13):4781-92. PubMed ID: 21634396
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of potent and selective histamine H3 receptor inverse agonists based on the 3,4-dihydro-2H-pyrazino[1,2-a]indol-1-one scaffold.
    Richter HG; Freichel C; Huwyler J; Nakagawa T; Nettekoven M; Plancher JM; Raab S; Roche O; Schuler F; Taylor S; Ullmer C; Wiegand R
    Bioorg Med Chem Lett; 2010 Oct; 20(19):5713-7. PubMed ID: 20801030
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H3 receptor antagonists.
    Rao AU; Palani A; Chen X; Huang Y; Aslanian RG; West RE; Williams SM; Wu RL; Hwa J; Sondey C; Lachowicz J
    Bioorg Med Chem Lett; 2009 Nov; 19(21):6176-80. PubMed ID: 19773164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A new class of histamine H3 receptor antagonists derived from ligand based design.
    Roche O; Rodríguez Sarmiento RM
    Bioorg Med Chem Lett; 2007 Jul; 17(13):3670-5. PubMed ID: 17498953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.
    Kitbunnadaj R; Zuiderveld OP; De Esch IJ; Vollinga RC; Bakker R; Lutz M; Spek AL; Cavoy E; Deltent MF; Menge WM; Timmerman H; Leurs R
    J Med Chem; 2003 Dec; 46(25):5445-57. PubMed ID: 14640553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.