BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

298 related articles for article (PubMed ID: 20044351)

  • 1. Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/beta-catenin targets.
    Weise A; Bruser K; Elfert S; Wallmen B; Wittel Y; Wöhrle S; Hecht A
    Nucleic Acids Res; 2010 Apr; 38(6):1964-81. PubMed ID: 20044351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression.
    Wallmen B; Schrempp M; Hecht A
    Nucleic Acids Res; 2012 Oct; 40(19):9455-69. PubMed ID: 22859735
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.
    Shitashige M; Naishiro Y; Idogawa M; Honda K; Ono M; Hirohashi S; Yamada T
    Gastroenterology; 2007 Mar; 132(3):1039-54. PubMed ID: 17383426
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid-enhancer factor (TCF/LEF)-dependent target genes.
    Locke JM; Da Silva Xavier G; Rutter GA; Harries LW
    Diabetologia; 2011 Dec; 54(12):3078-82. PubMed ID: 21913056
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner.
    Struewing I; Boyechko T; Barnett C; Beildeck M; Byers SW; Mao CD
    Biochem Biophys Res Commun; 2010 Aug; 399(2):245-50. PubMed ID: 20654575
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Acetylation of human TCF4 (TCF7L2) proteins attenuates inhibition by the HBP1 repressor and induces a conformational change in the TCF4::DNA complex.
    Elfert S; Weise A; Bruser K; Biniossek ML; Jägle S; Senghaas N; Hecht A
    PLoS One; 2013; 8(4):e61867. PubMed ID: 23613959
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genotype and tissue-specific effects on alternative splicing of the transcription factor 7-like 2 gene in humans.
    Mondal AK; Das SK; Baldini G; Chu WS; Sharma NK; Hackney OG; Zhao J; Grant SF; Elbein SC
    J Clin Endocrinol Metab; 2010 Mar; 95(3):1450-7. PubMed ID: 20097709
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A unique DNA binding domain converts T-cell factors into strong Wnt effectors.
    Atcha FA; Syed A; Wu B; Hoverter NP; Yokoyama NN; Ting JH; Munguia JE; Mangalam HJ; Marsh JL; Waterman ML
    Mol Cell Biol; 2007 Dec; 27(23):8352-63. PubMed ID: 17893322
    [TBL] [Abstract][Full Text] [Related]  

  • 9. How do they do Wnt they do?: regulation of transcription by the Wnt/β-catenin pathway.
    Archbold HC; Yang YX; Chen L; Cadigan KM
    Acta Physiol (Oxf); 2012 Jan; 204(1):74-109. PubMed ID: 21624092
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling.
    Idogawa M; Masutani M; Shitashige M; Honda K; Tokino T; Shinomura Y; Imai K; Hirohashi S; Yamada T
    Cancer Res; 2007 Feb; 67(3):911-8. PubMed ID: 17283121
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of members of the Wnt signaling pathway in the embryonic pituitary gland.
    Douglas KR; Brinkmeier ML; Kennell JA; Eswara P; Harrison TA; Patrianakos AI; Sprecher BS; Potok MA; Lyons RH; MacDougald OA; Camper SA
    Mamm Genome; 2001 Nov; 12(11):843-51. PubMed ID: 11845287
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear Dvl, c-Jun, beta-catenin, and TCF form a complex leading to stabilization of beta-catenin-TCF interaction.
    Gan XQ; Wang JY; Xi Y; Wu ZL; Li YP; Li L
    J Cell Biol; 2008 Mar; 180(6):1087-100. PubMed ID: 18347071
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain.
    Nagalski A; Irimia M; Szewczyk L; Ferran JL; Misztal K; Kuznicki J; Wisniewska MB
    Brain Struct Funct; 2013 Nov; 218(6):1531-49. PubMed ID: 23152144
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcription factor Egr1 acts as an upstream regulator of beta-catenin signalling through up-regulation of TCF4 and p300 expression during trans-differentiation of endometrial carcinoma cells.
    Saegusa M; Hashimura M; Kuwata T; Hamano M; Watanabe J; Kawaguchi M; Okayasu I
    J Pathol; 2008 Dec; 216(4):521-32. PubMed ID: 18798221
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The murine gastrin promoter is synergistically activated by transforming growth factor-beta/Smad and Wnt signaling pathways.
    Lei S; Dubeykovskiy A; Chakladar A; Wojtukiewicz L; Wang TC
    J Biol Chem; 2004 Oct; 279(41):42492-502. PubMed ID: 15292219
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.
    Mikels AJ; Nusse R
    PLoS Biol; 2006 Apr; 4(4):e115. PubMed ID: 16602827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The kinase TNIK is an essential activator of Wnt target genes.
    Mahmoudi T; Li VS; Ng SS; Taouatas N; Vries RG; Mohammed S; Heck AJ; Clevers H
    EMBO J; 2009 Nov; 28(21):3329-40. PubMed ID: 19816403
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of a promoter-specific transcriptional activation domain at the C terminus of the Wnt effector protein T-cell factor 4.
    Hecht A; Stemmler MP
    J Biol Chem; 2003 Feb; 278(6):3776-85. PubMed ID: 12446687
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Smad2 functions as a co-activator of canonical Wnt/beta-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300.
    Hirota M; Watanabe K; Hamada S; Sun Y; Strizzi L; Mancino M; Nagaoka T; Gonzales M; Seno M; Bianco C; Salomon DS
    Cell Signal; 2008 Sep; 20(9):1632-41. PubMed ID: 18595660
    [TBL] [Abstract][Full Text] [Related]  

  • 20. VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs.
    Zhang H; Rong X; Wang C; Liu Y; Lu L; Li Y; Zhao C; Zhou J
    J Biol Chem; 2020 Dec; 295(49):16826-16839. PubMed ID: 32989053
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.