BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 20046832)

  • 1. Avicin D, a plant triterpenoid, induces cell apoptosis by recruitment of Fas and downstream signaling molecules into lipid rafts.
    Xu ZX; Ding T; Haridas V; Connolly F; Gutterman JU
    PLoS One; 2009 Dec; 4(12):e8532. PubMed ID: 20046832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Edelfosine and perifosine induce selective apoptosis in multiple myeloma by recruitment of death receptors and downstream signaling molecules into lipid rafts.
    Gajate C; Mollinedo F
    Blood; 2007 Jan; 109(2):711-9. PubMed ID: 17003375
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells.
    Gajate C; Gonzalez-Camacho F; Mollinedo F
    PLoS One; 2009; 4(4):e5044. PubMed ID: 19352436
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Urokinase plasminogen activator receptor and/or matrix metalloproteinase-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells.
    Chetty C; Lakka SS; Bhoopathi P; Gondi CS; Veeravalli KK; Fassett D; Klopfenstein JD; Dinh DH; Gujrati M; Rao JS
    Mol Cancer Ther; 2010 Sep; 9(9):2605-17. PubMed ID: 20716639
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The anticancer plant triterpenoid, avicin D, regulates glucocorticoid receptor signaling: implications for cellular metabolism.
    Haridas V; Xu ZX; Kitchen D; Jiang A; Michels P; Gutterman JU
    PLoS One; 2011; 6(11):e28037. PubMed ID: 22132201
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Resveratrol-induced apoptosis is associated with Fas redistribution in the rafts and the formation of a death-inducing signaling complex in colon cancer cells.
    Delmas D; Rébé C; Lacour S; Filomenko R; Athias A; Gambert P; Cherkaoui-Malki M; Jannin B; Dubrez-Daloz L; Latruffe N; Solary E
    J Biol Chem; 2003 Oct; 278(42):41482-90. PubMed ID: 12902349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
    Reis-Sobreiro M; Gajate C; Mollinedo F
    Oncogene; 2009 Sep; 28(36):3221-34. PubMed ID: 19561642
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cytoskeleton-mediated death receptor and ligand concentration in lipid rafts forms apoptosis-promoting clusters in cancer chemotherapy.
    Gajate C; Mollinedo F
    J Biol Chem; 2005 Mar; 280(12):11641-7. PubMed ID: 15659383
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase.
    Xu ZX; Liang J; Haridas V; Gaikwad A; Connolly FP; Mills GB; Gutterman JU
    Cell Death Differ; 2007 Nov; 14(11):1948-57. PubMed ID: 17690712
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy.
    Mollinedo F; Gajate C
    Biochem Soc Trans; 2022 Jun; 50(3):1105-1118. PubMed ID: 35587168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. By activating Fas/ceramide synthase 6/p38 kinase in lipid rafts, stichoposide D inhibits growth of leukemia xenografts.
    Yun SH; Park ES; Shin SW; Ju MH; Han JY; Jeong JS; Kim SH; Stonik VA; Kwak JY; Park JI
    Oncotarget; 2015 Sep; 6(29):27596-612. PubMed ID: 26318294
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipid rafts and Fas/CD95 signaling in cancer chemotherapy.
    Gajate C; Mollinedo F
    Recent Pat Anticancer Drug Discov; 2011 Sep; 6(3):274-83. PubMed ID: 21762074
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death.
    Aouad SM; Cohen LY; Sharif-Askari E; Haddad EK; Alam A; Sekaly RP
    J Immunol; 2004 Feb; 172(4):2316-23. PubMed ID: 14764700
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The antitumor ether lipid ET-18-OCH(3) induces apoptosis through translocation and capping of Fas/CD95 into membrane rafts in human leukemic cells.
    Gajate C; Mollinedo F
    Blood; 2001 Dec; 98(13):3860-3. PubMed ID: 11739199
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fas signaling induces raft coalescence that is blocked by cholesterol depletion in human RPE cells undergoing apoptosis.
    Lincoln JE; Boling M; Parikh AN; Yeh Y; Gilchrist DG; Morse LS
    Invest Ophthalmol Vis Sci; 2006 May; 47(5):2172-8. PubMed ID: 16639029
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proapoptotic triterpene electrophiles (avicins) form channels in membranes: cholesterol dependence.
    Li XX; Davis B; Haridas V; Gutterman JU; Colombini M
    Biophys J; 2005 Apr; 88(4):2577-84. PubMed ID: 15653745
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lipid Raft Isolation by Sucrose Gradient Centrifugation and Visualization of Raft-Located Proteins by Fluorescence Microscopy: The Use of Combined Techniques to Assess Fas/CD95 Location in Rafts During Apoptosis Triggering.
    Gajate C; Mollinedo F
    Methods Mol Biol; 2021; 2187():147-186. PubMed ID: 32770506
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Triterpenoid saponins from Acacia victoriae (Bentham) decrease tumor cell proliferation and induce apoptosis.
    Mujoo K; Haridas V; Hoffmann JJ; Wächter GA; Hutter LK; Lu Y; Blake ME; Jayatilake GS; Bailey D; Mills GB; Gutterman JU
    Cancer Res; 2001 Jul; 61(14):5486-90. PubMed ID: 11454696
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DR5-mediated DISC controls caspase-8 cleavage and initiation of apoptosis in human glioblastomas.
    Bellail AC; Tse MC; Song JH; Phuphanich S; Olson JJ; Sun SY; Hao C
    J Cell Mol Med; 2010 Jun; 14(6A):1303-17. PubMed ID: 19432816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Avicins, a family of triterpenoid saponins from Acacia victoriae (Bentham), inhibit activation of nuclear factor-kappaB by inhibiting both its nuclear localization and ability to bind DNA.
    Haridas V; Arntzen CJ; Gutterman JU
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11557-62. PubMed ID: 11572998
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.