BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 20047156)

  • 1. The tetrahydrobiopterin pathway and pain.
    Naylor AM; Pojasek KR; Hopkins AL; Blagg J
    Curr Opin Investig Drugs; 2010 Jan; 11(1):19-30. PubMed ID: 20047156
    [TBL] [Abstract][Full Text] [Related]  

  • 2. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence.
    Tegeder I; Costigan M; Griffin RS; Abele A; Belfer I; Schmidt H; Ehnert C; Nejim J; Marian C; Scholz J; Wu T; Allchorne A; Diatchenko L; Binshtok AM; Goldman D; Adolph J; Sama S; Atlas SJ; Carlezon WA; Parsegian A; Lötsch J; Fillingim RB; Maixner W; Geisslinger G; Max MB; Woolf CJ
    Nat Med; 2006 Nov; 12(11):1269-77. PubMed ID: 17057711
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The pathway from GTP to tetrahydrobiopterin: three-dimensional structures of GTP cyclohydrolase I and 6-pyruvoyl tetrahydropterin synthase.
    Auerbach G; Nar H
    Biol Chem; 1997; 378(3-4):185-92. PubMed ID: 9165069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activity of synthetic enzymes of tetrahydrobiopterin in the human placenta.
    Iwanaga N; Yamamasu S; Tachibana D; Nishio J; Nakai Y; Shintaku H; Ishiko O
    Int J Mol Med; 2004 Jan; 13(1):117-20. PubMed ID: 14654981
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
    Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
    Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. GCH1, BH4 and pain.
    Latremoliere A; Costigan M
    Curr Pharm Biotechnol; 2011 Oct; 12(10):1728-41. PubMed ID: 21466440
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Effects of depletion of intracellular tetrahydrobiopterin in murine erythroleukemia cells.
    Zhuo S; Fan S; Kaufman S
    Exp Cell Res; 1996 Jan; 222(1):163-70. PubMed ID: 8549660
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in the BH4-metabolizing genes GTP cyclohydrolase I, 6-pyruvoyl-tetrahydropterin synthase, sepiapterin reductase, carbinolamine-4a-dehydratase, and dihydropteridine reductase.
    Thöny B; Blau N
    Hum Mutat; 2006 Sep; 27(9):870-8. PubMed ID: 16917893
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combining Human and Rodent Genetics to Identify New Analgesics.
    Latremoliere A; Costigan M
    Neurosci Bull; 2018 Feb; 34(1):143-155. PubMed ID: 28667479
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The neurobiology of tetrahydrobiopterin biosynthesis: a model for regulation of GTP cyclohydrolase I gene transcription within nigrostriatal dopamine neurons.
    Kapatos G
    IUBMB Life; 2013 Apr; 65(4):323-33. PubMed ID: 23457032
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The metabolite BH4 controls T cell proliferation in autoimmunity and cancer.
    Cronin SJF; Seehus C; Weidinger A; Talbot S; Reissig S; Seifert M; Pierson Y; McNeill E; Longhi MS; Turnes BL; Kreslavsky T; Kogler M; Hoffmann D; Ticevic M; da Luz Scheffer D; Tortola L; Cikes D; Jais A; Rangachari M; Rao S; Paolino M; Novatchkova M; Aichinger M; Barrett L; Latremoliere A; Wirnsberger G; Lametschwandtner G; Busslinger M; Zicha S; Latini A; Robson SC; Waisman A; Andrews N; Costigan M; Channon KM; Weiss G; Kozlov AV; Tebbe M; Johnsson K; Woolf CJ; Penninger JM
    Nature; 2018 Nov; 563(7732):564-568. PubMed ID: 30405245
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzymatic synthesis of 6R-[U-14C]tetrahydrobiopterin from [U-14C]GTP.
    Hatakeyama K; Hoshiga M; Suzuki S; Kagamiyama H
    Anal Biochem; 1993 Feb; 209(1):1-5. PubMed ID: 8465941
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tetrahydrobiopterin deficiencies without hyperphenylalaninemia: diagnosis and genetics of dopa-responsive dystonia and sepiapterin reductase deficiency.
    Blau N; Bonafé L; Thöny B
    Mol Genet Metab; 2001; 74(1-2):172-85. PubMed ID: 11592814
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Analgesia by inhibiting tetrahydrobiopterin synthesis.
    Costigan M; Latremoliere A; Woolf CJ
    Curr Opin Pharmacol; 2012 Feb; 12(1):92-9. PubMed ID: 22178186
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alterations in dopamine and glutamate neurotransmission in tetrahydrobiopterin deficient spr-/- mice: relevance to schizophrenia.
    Choi YK; Tarazi FI
    BMB Rep; 2010 Sep; 43(9):593-8. PubMed ID: 20846490
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
    Hussein D; Starr A; Heikal L; McNeill E; Channon KM; Brown PR; Sutton BJ; McDonnell JM; Nandi M
    Br J Pharmacol; 2015 Aug; 172(16):4146-57. PubMed ID: 26014146
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cross-sectional assessment of the consequences of a GTP cyclohydrolase 1 haplotype for specialized tertiary outpatient pain care.
    Doehring A; Freynhagen R; Griessinger N; Zimmermann M; Sittl R; Hentig Nv; Geisslinger G; Lötsch J
    Clin J Pain; 2009; 25(9):781-5. PubMed ID: 19851158
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mast cell tetrahydrobiopterin contributes to itch in mice.
    Zschiebsch K; Fischer C; Wilken-Schmitz A; Geisslinger G; Channon K; Watschinger K; Tegeder I
    J Cell Mol Med; 2019 Feb; 23(2):985-1000. PubMed ID: 30450838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through activation of the Jak2 tyrosine kinase pathway in vascular endothelial cells.
    Shimizu S; Hiroi T; Ishii M; Hagiwara T; Wajima T; Miyazaki A; Kiuchi Y
    Int J Biochem Cell Biol; 2008; 40(4):755-65. PubMed ID: 18054268
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.
    Doehring A; Antoniades C; Channon KM; Tegeder I; Lötsch J
    Mutat Res; 2008; 659(3):195-201. PubMed ID: 18515178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.