These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
22. Integrity of kindlin-2 FERM subdomains is required for supporting integrin activation. Xu Z; Gao J; Hong J; Ma YQ Biochem Biophys Res Commun; 2013 May; 434(2):382-7. PubMed ID: 23578664 [TBL] [Abstract][Full Text] [Related]
23. Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain. Fujimoto TT; Katsutani S; Shimomura T; Fujimura K J Biol Chem; 2003 Jul; 278(29):26655-65. PubMed ID: 12736272 [TBL] [Abstract][Full Text] [Related]
24. The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation. Vanhoorelbeke K; De Meyer SF; Pareyn I; Melchior C; Plançon S; Margue C; Pradier O; Fondu P; Kieffer N; Springer TA; Deckmyn H J Biol Chem; 2009 May; 284(22):14914-20. PubMed ID: 19329429 [TBL] [Abstract][Full Text] [Related]
25. Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Cryo-Microscopy. Hanein D; Volkmann N Subcell Biochem; 2018; 87():353-363. PubMed ID: 29464566 [TBL] [Abstract][Full Text] [Related]
26. Intermolecular transmembrane domain interactions activate integrin αIIbβ3. Ye F; Kim SJ; Kim C J Biol Chem; 2014 Jun; 289(26):18507-13. PubMed ID: 24838247 [TBL] [Abstract][Full Text] [Related]
27. The mechanism of kindlin-mediated activation of integrin αIIbβ3. Ye F; Petrich BG; Anekal P; Lefort CT; Kasirer-Friede A; Shattil SJ; Ruppert R; Moser M; Fässler R; Ginsberg MH Curr Biol; 2013 Nov; 23(22):2288-2295. PubMed ID: 24210614 [TBL] [Abstract][Full Text] [Related]
28. Talin binding to integrin beta tails: a final common step in integrin activation. Tadokoro S; Shattil SJ; Eto K; Tai V; Liddington RC; de Pereda JM; Ginsberg MH; Calderwood DA Science; 2003 Oct; 302(5642):103-6. PubMed ID: 14526080 [TBL] [Abstract][Full Text] [Related]
29. The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation. Chinthalapudi K; Rangarajan ES; Izard T Proc Natl Acad Sci U S A; 2018 Oct; 115(41):10339-10344. PubMed ID: 30254158 [TBL] [Abstract][Full Text] [Related]
31. UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin alphaIIbbeta3. Verhaar R; Dekkers DW; De Cuyper IM; Ginsberg MH; de Korte D; Verhoeven AJ Blood; 2008 Dec; 112(13):4935-9. PubMed ID: 18796633 [TBL] [Abstract][Full Text] [Related]
32. Transmembrane domain helix packing stabilizes integrin alphaIIbbeta3 in the low affinity state. Partridge AW; Liu S; Kim S; Bowie JU; Ginsberg MH J Biol Chem; 2005 Feb; 280(8):7294-300. PubMed ID: 15591321 [TBL] [Abstract][Full Text] [Related]
33. Integrin αIIbβ3 transmembrane domain separation mediates bi-directional signaling across the plasma membrane. Hu P; Luo BH PLoS One; 2015; 10(1):e0116208. PubMed ID: 25617834 [TBL] [Abstract][Full Text] [Related]
34. Three-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin Complexes. Xu XP; Kim E; Swift M; Smith JW; Volkmann N; Hanein D Biophys J; 2016 Feb; 110(4):798-809. PubMed ID: 26910421 [TBL] [Abstract][Full Text] [Related]
35. Interactions of platelet integrin alphaIIb and beta3 transmembrane domains in mammalian cell membranes and their role in integrin activation. Kim C; Lau TL; Ulmer TS; Ginsberg MH Blood; 2009 May; 113(19):4747-53. PubMed ID: 19218549 [TBL] [Abstract][Full Text] [Related]
36. A new functional role of the fibrinogen RGD motif as the molecular switch that selectively triggers integrin alphaIIbbeta3-dependent RhoA activation during cell spreading. Salsmann A; Schaffner-Reckinger E; Kabile F; Plançon S; Kieffer N J Biol Chem; 2005 Sep; 280(39):33610-9. PubMed ID: 15955823 [TBL] [Abstract][Full Text] [Related]
37. Serine 752 in the cytoplasmic domain of the beta 3 integrin subunit is not required for alpha v beta 3 postreceptor signaling events. Kieffer N; Melchior C; Guinet JM; Michels S; Gouon V; Bron N Cell Adhes Commun; 1996 Jul; 4(1):25-39. PubMed ID: 8870971 [TBL] [Abstract][Full Text] [Related]
38. Kindlin supports platelet integrin αIIbβ3 activation by interacting with paxillin. Gao J; Huang M; Lai J; Mao K; Sun P; Cao Z; Hu Y; Zhang Y; Schulte ML; Jin C; Wang J; White GC; Xu Z; Ma YQ J Cell Sci; 2017 Nov; 130(21):3764-3775. PubMed ID: 28954813 [TBL] [Abstract][Full Text] [Related]
39. Suppression of integrin activation by the membrane-distal sequence of the integrin alphaIIb cytoplasmic tail. Yamanouchi J; Hato T; Tamura T; Fujita S Biochem J; 2004 Apr; 379(Pt 2):317-23. PubMed ID: 14723599 [TBL] [Abstract][Full Text] [Related]