300 related articles for article (PubMed ID: 20051520)
1. The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.
Matsunaga-Udagawa R; Fujita Y; Yoshiki S; Terai K; Kamioka Y; Kiyokawa E; Yugi K; Aoki K; Matsuda M
J Biol Chem; 2010 Mar; 285(10):7818-26. PubMed ID: 20051520
[TBL] [Abstract][Full Text] [Related]
2. Shoc2/Sur8 protein regulates neurite outgrowth.
Leon G; Sanchez-Ruiloba L; Perez-Rodriguez A; Gragera T; Martinez N; Hernandez S; Anta B; Calero O; Garcia-Dominguez CA; Dura LM; Peña-Jimenez D; Castro J; Zarich N; Sanchez-Gomez P; Calero M; Iglesias T; Oliva JL; Rojas JM
PLoS One; 2014; 9(12):e114837. PubMed ID: 25514808
[TBL] [Abstract][Full Text] [Related]
3. SHOC2 complex-driven RAF dimerization selectively contributes to ERK pathway dynamics.
Boned Del Río I; Young LC; Sari S; Jones GG; Ringham-Terry B; Hartig N; Rejnowicz E; Lei W; Bhamra A; Surinova S; Rodriguez-Viciana P
Proc Natl Acad Sci U S A; 2019 Jul; 116(27):13330-13339. PubMed ID: 31213532
[TBL] [Abstract][Full Text] [Related]
4. Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein.
Yoshiki S; Matsunaga-Udagawa R; Aoki K; Kamioka Y; Kiyokawa E; Matsuda M
Mol Biol Cell; 2010 Mar; 21(6):1088-96. PubMed ID: 20071468
[TBL] [Abstract][Full Text] [Related]
5. SHOC2-MRAS-PP1 complex positively regulates RAF activity and contributes to Noonan syndrome pathogenesis.
Young LC; Hartig N; Boned Del Río I; Sari S; Ringham-Terry B; Wainwright JR; Jones GG; McCormick F; Rodriguez-Viciana P
Proc Natl Acad Sci U S A; 2018 Nov; 115(45):E10576-E10585. PubMed ID: 30348783
[TBL] [Abstract][Full Text] [Related]
6. Shoc2 is targeted to late endosomes and required for Erk1/2 activation in EGF-stimulated cells.
Galperin E; Abdelmoti L; Sorkin A
PLoS One; 2012; 7(5):e36469. PubMed ID: 22606262
[TBL] [Abstract][Full Text] [Related]
7. Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling.
Kaduwal S; Jeong WJ; Park JC; Lee KH; Lee YM; Jeon SH; Lim YB; Min do S; Choi KY
Oncotarget; 2015 Oct; 6(32):33091-105. PubMed ID: 26384305
[TBL] [Abstract][Full Text] [Related]
8. SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers.
Jones GG; Del Río IB; Sari S; Sekerim A; Young LC; Hartig N; Areso Zubiaur I; El-Bahrawy MA; Hynds RE; Lei W; Molina-Arcas M; Downward J; Rodriguez-Viciana P
Nat Commun; 2019 Jun; 10(1):2532. PubMed ID: 31182717
[TBL] [Abstract][Full Text] [Related]
9. Structural basis for SHOC2 modulation of RAS signalling.
Liau NPD; Johnson MC; Izadi S; Gerosa L; Hammel M; Bruning JM; Wendorff TJ; Phung W; Hymowitz SG; Sudhamsu J
Nature; 2022 Sep; 609(7926):400-407. PubMed ID: 35768504
[TBL] [Abstract][Full Text] [Related]
10. Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome.
Bonsor DA; Alexander P; Snead K; Hartig N; Drew M; Messing S; Finci LI; Nissley DV; McCormick F; Esposito D; Rodriguez-Viciana P; Stephen AG; Simanshu DK
Nat Struct Mol Biol; 2022 Oct; 29(10):966-977. PubMed ID: 36175670
[TBL] [Abstract][Full Text] [Related]
11. A phosphatase holoenzyme comprised of Shoc2/Sur8 and the catalytic subunit of PP1 functions as an M-Ras effector to modulate Raf activity.
Rodriguez-Viciana P; Oses-Prieto J; Burlingame A; Fried M; McCormick F
Mol Cell; 2006 Apr; 22(2):217-30. PubMed ID: 16630891
[TBL] [Abstract][Full Text] [Related]
12. Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes.
Fujioka A; Terai K; Itoh RE; Aoki K; Nakamura T; Kuroda S; Nishida E; Matsuda M
J Biol Chem; 2006 Mar; 281(13):8917-26. PubMed ID: 16418172
[TBL] [Abstract][Full Text] [Related]
13. RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF.
Poulikakos PI; Zhang C; Bollag G; Shokat KM; Rosen N
Nature; 2010 Mar; 464(7287):427-30. PubMed ID: 20179705
[TBL] [Abstract][Full Text] [Related]
14. Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration.
Rajalingam K; Wunder C; Brinkmann V; Churin Y; Hekman M; Sievers C; Rapp UR; Rudel T
Nat Cell Biol; 2005 Aug; 7(8):837-43. PubMed ID: 16041367
[TBL] [Abstract][Full Text] [Related]
15. An MRAS, SHOC2, and SCRIB complex coordinates ERK pathway activation with polarity and tumorigenic growth.
Young LC; Hartig N; Muñoz-Alegre M; Oses-Prieto JA; Durdu S; Bender S; Vijayakumar V; Vietri Rudan M; Gewinner C; Henderson S; Jathoul AP; Ghatrora R; Lythgoe MF; Burlingame AL; Rodriguez-Viciana P
Mol Cell; 2013 Dec; 52(5):679-92. PubMed ID: 24211266
[TBL] [Abstract][Full Text] [Related]
16. The FBXW7-SHOC2-Raptor Axis Controls the Cross-Talks between the RAS-ERK and mTORC1 Signaling Pathways.
Xie CM; Tan M; Lin XT; Wu D; Jiang Y; Tan Y; Li H; Ma Y; Xiong X; Sun Y
Cell Rep; 2019 Mar; 26(11):3037-3050.e4. PubMed ID: 30865892
[TBL] [Abstract][Full Text] [Related]
17. Pathway crosstalk between Ras/Raf and PI3K in promotion of M-CSF-induced MEK/ERK-mediated osteoclast survival.
Bradley EW; Ruan MM; Vrable A; Oursler MJ
J Cell Biochem; 2008 Jul; 104(4):1439-51. PubMed ID: 18275061
[TBL] [Abstract][Full Text] [Related]
18. HOXA3 promotes tumor growth of human colon cancer through activating EGFR/Ras/Raf/MEK/ERK signaling pathway.
Zhang X; Liu G; Ding L; Jiang T; Shao S; Gao Y; Lu Y
J Cell Biochem; 2018 Mar; 119(3):2864-2874. PubMed ID: 29073728
[TBL] [Abstract][Full Text] [Related]
19. Bromodomain containing protein represses the Ras/Raf/MEK/ERK pathway to attenuate human hepatoma cell proliferation during HCV infection.
Zhang Q; Wei L; Yang H; Yang W; Yang Q; Zhang Z; Wu K; Wu J
Cancer Lett; 2016 Feb; 371(1):107-16. PubMed ID: 26620707
[TBL] [Abstract][Full Text] [Related]
20. RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.
Hatzivassiliou G; Song K; Yen I; Brandhuber BJ; Anderson DJ; Alvarado R; Ludlam MJ; Stokoe D; Gloor SL; Vigers G; Morales T; Aliagas I; Liu B; Sideris S; Hoeflich KP; Jaiswal BS; Seshagiri S; Koeppen H; Belvin M; Friedman LS; Malek S
Nature; 2010 Mar; 464(7287):431-5. PubMed ID: 20130576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
