165 related articles for article (PubMed ID: 20053636)
1. LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse.
Sakane H; Yamamoto H; Kikuchi A
J Cell Sci; 2010 Feb; 123(Pt 3):360-8. PubMed ID: 20053636
[TBL] [Abstract][Full Text] [Related]
2. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling.
Yamamoto H; Sakane H; Yamamoto H; Michiue T; Kikuchi A
Dev Cell; 2008 Jul; 15(1):37-48. PubMed ID: 18606139
[TBL] [Abstract][Full Text] [Related]
3. Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.
Bourhis E; Tam C; Franke Y; Bazan JF; Ernst J; Hwang J; Costa M; Cochran AG; Hannoush RN
J Biol Chem; 2010 Mar; 285(12):9172-9. PubMed ID: 20093360
[TBL] [Abstract][Full Text] [Related]
4. The first propeller domain of LRP6 regulates sensitivity to DKK1.
Binnerts ME; Tomasevic N; Bright JM; Leung J; Ahn VE; Kim KA; Zhan X; Liu S; Yonkovich S; Williams J; Zhou M; Gros D; Dixon M; Korver W; Weis WI; Abo A
Mol Biol Cell; 2009 Aug; 20(15):3552-60. PubMed ID: 19477926
[TBL] [Abstract][Full Text] [Related]
5. DKK1 antagonizes Wnt signaling without promotion of LRP6 internalization and degradation.
Semënov MV; Zhang X; He X
J Biol Chem; 2008 Aug; 283(31):21427-32. PubMed ID: 18505732
[TBL] [Abstract][Full Text] [Related]
6. Mesd is a universal inhibitor of Wnt coreceptors LRP5 and LRP6 and blocks Wnt/beta-catenin signaling in cancer cells.
Lu W; Liu CC; Thottassery JV; Bu G; Li Y
Biochemistry; 2010 Jun; 49(22):4635-43. PubMed ID: 20446724
[TBL] [Abstract][Full Text] [Related]
7. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6.
Binnerts ME; Kim KA; Bright JM; Patel SM; Tran K; Zhou M; Leung JM; Liu Y; Lomas WE; Dixon M; Hazell SA; Wagle M; Nie WS; Tomasevic N; Williams J; Zhan X; Levy MD; Funk WD; Abo A
Proc Natl Acad Sci U S A; 2007 Sep; 104(37):14700-5. PubMed ID: 17804805
[TBL] [Abstract][Full Text] [Related]
8. Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling.
Sakane H; Yamamoto H; Matsumoto S; Sato A; Kikuchi A
J Cell Sci; 2012 Jan; 125(Pt 2):449-60. PubMed ID: 22302992
[TBL] [Abstract][Full Text] [Related]
9. Evidence for non-functional Dickkopf-1 (DKK-1) signaling in chronic lymphocytic leukemia (CLL).
Filipovich A; Gandhirajan RK; Gehrke I; Poll-Wolbeck SJ; Kreuzer KA
Eur J Haematol; 2010 Oct; 85(4):309-13. PubMed ID: 20618428
[TBL] [Abstract][Full Text] [Related]
10. Inhibition of tumorigenesis driven by different Wnt proteins requires blockade of distinct ligand-binding regions by LRP6 antibodies.
Ettenberg SA; Charlat O; Daley MP; Liu S; Vincent KJ; Stuart DD; Schuller AG; Yuan J; Ospina B; Green J; Yu Q; Walsh R; Li S; Schmitz R; Heine H; Bilic S; Ostrom L; Mosher R; Hartlepp KF; Zhu Z; Fawell S; Yao YM; Stover D; Finan PM; Porter JA; Sellers WR; Klagge IM; Cong F
Proc Natl Acad Sci U S A; 2010 Aug; 107(35):15473-8. PubMed ID: 20713706
[TBL] [Abstract][Full Text] [Related]
11. Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.
Qiang YW; Barlogie B; Rudikoff S; Shaughnessy JD
Bone; 2008 Apr; 42(4):669-80. PubMed ID: 18294945
[TBL] [Abstract][Full Text] [Related]
12. Negative regulation of LRP6 function by casein kinase I epsilon phosphorylation.
Swiatek W; Kang H; Garcia BA; Shabanowitz J; Coombs GS; Hunt DF; Virshup DM
J Biol Chem; 2006 May; 281(18):12233-41. PubMed ID: 16513652
[TBL] [Abstract][Full Text] [Related]
13. Dynamic palmitoylation controls the microdomain localization of the DKK1 receptors CKAP4 and LRP6.
Sada R; Kimura H; Fukata Y; Fukata M; Yamamoto H; Kikuchi A
Sci Signal; 2019 Nov; 12(608):. PubMed ID: 31744930
[TBL] [Abstract][Full Text] [Related]
14. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism.
Endo Y; Beauchamp E; Woods D; Taylor WG; Toretsky JA; Uren A; Rubin JS
Mol Cell Biol; 2008 Apr; 28(7):2368-79. PubMed ID: 18212053
[TBL] [Abstract][Full Text] [Related]
15. Wnt5a regulates distinct signalling pathways by binding to Frizzled2.
Sato A; Yamamoto H; Sakane H; Koyama H; Kikuchi A
EMBO J; 2010 Jan; 29(1):41-54. PubMed ID: 19910923
[TBL] [Abstract][Full Text] [Related]
16. Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation.
Tanneberger K; Pfister AS; Brauburger K; Schneikert J; Hadjihannas MV; Kriz V; Schulte G; Bryja V; Behrens J
EMBO J; 2011 Apr; 30(8):1433-43. PubMed ID: 21304492
[TBL] [Abstract][Full Text] [Related]
17. Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling.
von Marschall Z; Fisher LW
Biochem Biophys Res Commun; 2010 Sep; 400(3):299-304. PubMed ID: 20723538
[TBL] [Abstract][Full Text] [Related]
18. Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin.
Yamamoto H; Komekado H; Kikuchi A
Dev Cell; 2006 Aug; 11(2):213-23. PubMed ID: 16890161
[TBL] [Abstract][Full Text] [Related]
19. Bidirectional effect of Wnt signaling antagonist DKK1 on the modulation of anthrax toxin uptake.
Qian L; Cai C; Yuan P; Jeong SY; Yang X; Dealmeida V; Ernst J; Costa M; Cohen SN; Wei W
Sci China Life Sci; 2014 May; 57(5):469-81. PubMed ID: 24671437
[TBL] [Abstract][Full Text] [Related]
20. Wnt-independent activation of beta-catenin mediated by a Dkk1-Fz5 fusion protein.
Holmen SL; Robertson SA; Zylstra CR; Williams BO
Biochem Biophys Res Commun; 2005 Mar; 328(2):533-9. PubMed ID: 15694380
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]