BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

305 related articles for article (PubMed ID: 20060900)

  • 1. Prolyl-peptidyl isomerase, Pin1, phosphorylation is compromised in association with the expression of the HFE polymorphic allele, H63D.
    Hall EC; Lee SY; Simmons Z; Neely EB; Nandar W; Connor JR
    Biochim Biophys Acta; 2010 Apr; 1802(4):389-95. PubMed ID: 20060900
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of the HFE allelic variant H63D in SH-SY5Y cells affects tau phosphorylation at serine residues.
    Hall EC; Lee SY; Mairuae N; Simmons Z; Connor JR
    Neurobiol Aging; 2011 Aug; 32(8):1409-19. PubMed ID: 19775775
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effects of okra (Abelmoschus esculentus Linn.) on the cellular events associated with Alzheimer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line.
    Mairuae N; Connor JR; Lee SY; Cheepsunthorn P; Tongjaroenbuangam W
    Neurosci Lett; 2015 Aug; 603():6-11. PubMed ID: 26170247
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The H63D HFE gene variant promotes activation of the intrinsic apoptotic pathway via mitochondria dysfunction following β-amyloid peptide exposure.
    Mairuae N; Hall Ii EC; Cheepsunthorn P; Lee SY; Connor JR
    J Neurosci Res; 2010 Nov; 88(14):3079-89. PubMed ID: 20734416
    [TBL] [Abstract][Full Text] [Related]  

  • 5. H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment.
    Ali-Rahmani F; Grigson PS; Lee S; Neely E; Connor JR; Schengrund CL
    Neurobiol Aging; 2014 Jun; 35(6):1511.e1-12. PubMed ID: 24439478
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mutant HFE H63D protein is associated with prolonged endoplasmic reticulum stress and increased neuronal vulnerability.
    Liu Y; Lee SY; Neely E; Nandar W; Moyo M; Simmons Z; Connor JR
    J Biol Chem; 2011 Apr; 286(15):13161-70. PubMed ID: 21349849
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mutation in the HFE gene is associated with altered brain iron profiles and increased oxidative stress in mice.
    Nandar W; Neely EB; Unger E; Connor JR
    Biochim Biophys Acta; 2013 Jun; 1832(6):729-41. PubMed ID: 23429074
    [TBL] [Abstract][Full Text] [Related]  

  • 8. H63D HFE genotype accelerates disease progression in animal models of amyotrophic lateral sclerosis.
    Nandar W; Neely EB; Simmons Z; Connor JR
    Biochim Biophys Acta; 2014 Dec; 1842(12 Pt A):2413-26. PubMed ID: 25283820
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Utilizing the peptidyl-prolyl cis-trans isomerase pin1 as a probe of its phosphorylated target proteins. Examples of binding to nuclear proteins in a human kidney cell line and to tau in Alzheimer's diseased brain.
    Thorpe JR; Morley SJ; Rulten SL
    J Histochem Cytochem; 2001 Jan; 49(1):97-108. PubMed ID: 11118482
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.
    Rudrabhatla P; Zheng YL; Amin ND; Kesavapany S; Albers W; Pant HC
    J Biol Chem; 2008 Sep; 283(39):26737-47. PubMed ID: 18635547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
    Ando K; Dourlen P; Sambo AV; Bretteville A; Bélarbi K; Vingtdeux V; Eddarkaoui S; Drobecq H; Ghestem A; Bégard S; Demey-Thomas E; Melnyk P; Smet C; Lippens G; Maurage CA; Caillet-Boudin ML; Verdier Y; Vinh J; Landrieu I; Galas MC; Blum D; Hamdane M; Sergeant N; Buée L
    Neurobiol Aging; 2013 Mar; 34(3):757-69. PubMed ID: 22926167
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HFE polymorphisms affect cellular glutamate regulation.
    Mitchell RM; Lee SY; Simmons Z; Connor JR
    Neurobiol Aging; 2011 Jun; 32(6):1114-23. PubMed ID: 19560233
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pin1 allows for differential Tau dephosphorylation in neuronal cells.
    Hamdane M; Dourlen P; Bretteville A; Sambo AV; Ferreira S; Ando K; Kerdraon O; Bégard S; Geay L; Lippens G; Sergeant N; Delacourte A; Maurage CA; Galas MC; Buée L
    Mol Cell Neurosci; 2006; 32(1-2):155-60. PubMed ID: 16697218
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.
    Pastorino L; Sun A; Lu PJ; Zhou XZ; Balastik M; Finn G; Wulf G; Lim J; Li SH; Li X; Xia W; Nicholson LK; Lu KP
    Nature; 2006 Mar; 440(7083):528-34. PubMed ID: 16554819
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.
    Mitchell RM; Lee SY; Randazzo WT; Simmons Z; Connor JR
    J Neuroinflammation; 2009 Feb; 6():6. PubMed ID: 19228389
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA sequence variations in the prolyl isomerase Pin1 gene and Alzheimer's disease.
    Poli M; Gatta LB; Dominici R; Lovati C; Mariani C; Albertini A; Finazzi D
    Neurosci Lett; 2005 Dec; 389(2):66-70. PubMed ID: 16095818
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Prolyl isomerase Pin1 promotes amyloid precursor protein (APP) turnover by inhibiting glycogen synthase kinase-3β (GSK3β) activity: novel mechanism for Pin1 to protect against Alzheimer disease.
    Ma SL; Pastorino L; Zhou XZ; Lu KP
    J Biol Chem; 2012 Mar; 287(10):6969-73. PubMed ID: 22184106
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Oxidative modification and down-regulation of Pin1 in Alzheimer's disease hippocampus: A redox proteomics analysis.
    Sultana R; Boyd-Kimball D; Poon HF; Cai J; Pierce WM; Klein JB; Markesbery WR; Zhou XZ; Lu KP; Butterfield DA
    Neurobiol Aging; 2006 Jul; 27(7):918-25. PubMed ID: 15950321
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Consequences of expressing mutants of the hemochromatosis gene (HFE) into a human neuronal cell line lacking endogenous HFE.
    Lee SY; Patton SM; Henderson RJ; Connor JR
    FASEB J; 2007 Feb; 21(2):564-76. PubMed ID: 17194693
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease.
    Driver JA; Zhou XZ; Lu KP
    Biochim Biophys Acta; 2015 Oct; 1850(10):2069-76. PubMed ID: 25583562
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.