851 related articles for article (PubMed ID: 20061378)
1. SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.
Pacholec M; Bleasdale JE; Chrunyk B; Cunningham D; Flynn D; Garofalo RS; Griffith D; Griffor M; Loulakis P; Pabst B; Qiu X; Stockman B; Thanabal V; Varghese A; Ward J; Withka J; Ahn K
J Biol Chem; 2010 Mar; 285(11):8340-51. PubMed ID: 20061378
[TBL] [Abstract][Full Text] [Related]
2. Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo.
Smith JJ; Kenney RD; Gagne DJ; Frushour BP; Ladd W; Galonek HL; Israelian K; Song J; Razvadauskaite G; Lynch AV; Carney DP; Johnson RJ; Lavu S; Iffland A; Elliott PJ; Lambert PD; Elliston KO; Jirousek MR; Milne JC; Boss O
BMC Syst Biol; 2009 Mar; 3():31. PubMed ID: 19284563
[TBL] [Abstract][Full Text] [Related]
3. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes.
Milne JC; Lambert PD; Schenk S; Carney DP; Smith JJ; Gagne DJ; Jin L; Boss O; Perni RB; Vu CB; Bemis JE; Xie R; Disch JS; Ng PY; Nunes JJ; Lynch AV; Yang H; Galonek H; Israelian K; Choy W; Iffland A; Lavu S; Medvedik O; Sinclair DA; Olefsky JM; Jirousek MR; Elliott PJ; Westphal CH
Nature; 2007 Nov; 450(7170):712-6. PubMed ID: 18046409
[TBL] [Abstract][Full Text] [Related]
4. SIRT1-independent mechanisms of the putative sirtuin enzyme activators SRT1720 and SRT2183.
Huber JL; McBurney MW; Distefano PS; McDonagh T
Future Med Chem; 2010 Dec; 2(12):1751-9. PubMed ID: 21428798
[TBL] [Abstract][Full Text] [Related]
5. SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-κB/STAT3 complex to its promoter in malignant lymphoid cells.
Scuto A; Kirschbaum M; Buettner R; Kujawski M; Cermak JM; Atadja P; Jove R
Cell Death Dis; 2013 May; 4(5):e635. PubMed ID: 23681230
[TBL] [Abstract][Full Text] [Related]
6. Biochemical effects of SIRT1 activators.
Baur JA
Biochim Biophys Acta; 2010 Aug; 1804(8):1626-34. PubMed ID: 19897059
[TBL] [Abstract][Full Text] [Related]
7. Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing's sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity.
Sonnemann J; Kahl M; Siranjeevi PM; Blumrich A; Blümel L; Becker S; Wittig S; Winkler R; Krämer OH; Beck JF
J Cancer Res Clin Oncol; 2016 Jan; 142(1):17-26. PubMed ID: 26055805
[TBL] [Abstract][Full Text] [Related]
8. Mechanism of human SIRT1 activation by resveratrol.
Borra MT; Smith BC; Denu JM
J Biol Chem; 2005 Apr; 280(17):17187-95. PubMed ID: 15749705
[TBL] [Abstract][Full Text] [Related]
9. Alkylresorcinols activate SIRT1 and delay ageing in Drosophila melanogaster.
Kayashima Y; Katayanagi Y; Tanaka K; Fukutomi R; Hiramoto S; Imai S
Sci Rep; 2017 Mar; 7():43679. PubMed ID: 28252007
[TBL] [Abstract][Full Text] [Related]
10. SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease.
Wan X; Wen JJ; Koo SJ; Liang LY; Garg NJ
PLoS Pathog; 2016 Oct; 12(10):e1005954. PubMed ID: 27764247
[TBL] [Abstract][Full Text] [Related]
11. Novel SIRT1 activator MHY2233 improves glucose tolerance and reduces hepatic lipid accumulation in db/db mice.
Kim MJ; An HJ; Kim DH; Lee B; Lee HJ; Ullah S; Kim SJ; Jeong HO; Moon KM; Lee EK; Yang J; Akter J; Chun P; Moon HR; Chung HY
Bioorg Med Chem Lett; 2018 Feb; 28(4):684-688. PubMed ID: 29402742
[TBL] [Abstract][Full Text] [Related]
12. Evidence for a common mechanism of SIRT1 regulation by allosteric activators.
Hubbard BP; Gomes AP; Dai H; Li J; Case AW; Considine T; Riera TV; Lee JE; E SY; Lamming DW; Pentelute BL; Schuman ER; Stevens LA; Ling AJ; Armour SM; Michan S; Zhao H; Jiang Y; Sweitzer SM; Blum CA; Disch JS; Ng PY; Howitz KT; Rolo AP; Hamuro Y; Moss J; Perni RB; Ellis JL; Vlasuk GP; Sinclair DA
Science; 2013 Mar; 339(6124):1216-9. PubMed ID: 23471411
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol.
Cao D; Wang M; Qiu X; Liu D; Jiang H; Yang N; Xu RM
Genes Dev; 2015 Jun; 29(12):1316-25. PubMed ID: 26109052
[TBL] [Abstract][Full Text] [Related]
14. Sirt1 activation by resveratrol is substrate sequence-selective.
Lakshminarasimhan M; Rauh D; Schutkowski M; Steegborn C
Aging (Albany NY); 2013 Mar; 5(3):151-4. PubMed ID: 23524286
[TBL] [Abstract][Full Text] [Related]
15. Resveratrol is not a direct activator of SIRT1 enzyme activity.
Beher D; Wu J; Cumine S; Kim KW; Lu SC; Atangan L; Wang M
Chem Biol Drug Des; 2009 Dec; 74(6):619-24. PubMed ID: 19843076
[TBL] [Abstract][Full Text] [Related]
16. Resveratrol Protects Against Pulmonary Arterial Hypertension in Rats via Activation of Silent Information Regulator 1.
Yu L; Tu Y; Jia X; Fang K; Liu L; Wan L; Xiang C; Wang Y; Sun X; Liu T; Yu D; Cao W; Song Y; Fan Y
Cell Physiol Biochem; 2017; 42(1):55-67. PubMed ID: 28494457
[TBL] [Abstract][Full Text] [Related]
17. Resveratrol serves as a protein-substrate interaction stabilizer in human SIRT1 activation.
Hou X; Rooklin D; Fang H; Zhang Y
Sci Rep; 2016 Nov; 6():38186. PubMed ID: 27901083
[TBL] [Abstract][Full Text] [Related]
18. Mitochondrial biogenesis: pharmacological approaches.
Valero T
Curr Pharm Des; 2014; 20(35):5507-9. PubMed ID: 24606795
[TBL] [Abstract][Full Text] [Related]
19. A molecular mechanism for direct sirtuin activation by resveratrol.
Gertz M; Nguyen GT; Fischer F; Suenkel B; Schlicker C; Fränzel B; Tomaschewski J; Aladini F; Becker C; Wolters D; Steegborn C
PLoS One; 2012; 7(11):e49761. PubMed ID: 23185430
[TBL] [Abstract][Full Text] [Related]
20. SIRT1 activation by resveratrol ameliorates cisplatin-induced renal injury through deacetylation of p53.
Kim DH; Jung YJ; Lee JE; Lee AS; Kang KP; Lee S; Park SK; Han MK; Lee SY; Ramkumar KM; Sung MJ; Kim W
Am J Physiol Renal Physiol; 2011 Aug; 301(2):F427-35. PubMed ID: 21593185
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
