BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 2006139)

  • 21. Freezing a single distal motion in dihydrofolate reductase.
    Sergi A; Watney JB; Wong KF; Hammes-Schiffer S
    J Phys Chem B; 2006 Feb; 110(5):2435-41. PubMed ID: 16471835
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima.
    Maglia G; Javed MH; Allemann RK
    Biochem J; 2003 Sep; 374(Pt 2):529-35. PubMed ID: 12765545
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Effects of temperature and viscosity on R67 dihydrofolate reductase catalysis.
    Chopra S; Lynch R; Kim SH; Jackson M; Howell EE
    Biochemistry; 2006 May; 45(21):6596-605. PubMed ID: 16716070
    [TBL] [Abstract][Full Text] [Related]  

  • 24. 13C and 15N nuclear magnetic resonance evidence that the active site carboxyl group of dihydrofolate reductase is not involved in the relay of a proton to substrate.
    Blakley RL; Appleman JR; Freisheim JH; Jablonsky MJ
    Arch Biochem Biophys; 1993 Nov; 306(2):501-9. PubMed ID: 8105754
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Probing coupled motions in enzymatic hydrogen tunnelling reactions.
    Allemann RK; Evans RM; Loveridge EJ
    Biochem Soc Trans; 2009 Apr; 37(Pt 2):349-53. PubMed ID: 19290860
    [TBL] [Abstract][Full Text] [Related]  

  • 26. A perspective on enzyme catalysis.
    Benkovic SJ; Hammes-Schiffer S
    Science; 2003 Aug; 301(5637):1196-202. PubMed ID: 12947189
    [TBL] [Abstract][Full Text] [Related]  

  • 27. NMR-derived folate-bound structure of dihydrofolate reductase 1 from the halophile Haloferax volcanii.
    Boroujerdi AF; Young JK
    Biopolymers; 2009 Feb; 91(2):140-4. PubMed ID: 18825778
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Probing protein environment in an enzymatic process: All-electron quantum chemical analysis combined with ab initio quantum mechanical/molecular mechanical modeling of chorismate mutase.
    Ishida T
    J Chem Phys; 2008 Sep; 129(12):125105. PubMed ID: 19045066
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Kinetic reaction scheme for the dihydrofolate reductase domain of the bifunctional thymidylate synthase-dihydrofolate reductase from Leishmania major.
    Liang PH; Anderson KS
    Biochemistry; 1998 Sep; 37(35):12206-12. PubMed ID: 9724534
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Substrate channeling and domain-domain interactions in bifunctional thymidylate synthase-dihydrofolate reductase.
    Liang PH; Anderson KS
    Biochemistry; 1998 Sep; 37(35):12195-205. PubMed ID: 9724533
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Quantum-classical simulation methods for hydrogen transfer in enzymes: a case study of dihydrofolate reductase.
    Hammes-Schiffer S
    Curr Opin Struct Biol; 2004 Apr; 14(2):192-201. PubMed ID: 15093834
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Protein flexibility and species specificity in structure-based drug discovery: dihydrofolate reductase as a test system.
    Bowman AL; Lerner MG; Carlson HA
    J Am Chem Soc; 2007 Mar; 129(12):3634-40. PubMed ID: 17335207
    [TBL] [Abstract][Full Text] [Related]  

  • 33. "In situ" variation of folic acid and dihydrofolate reductase in the caudate nucleus in the ageing process.
    Diculescu I; Onicescu D
    J Hirnforsch; 1979; 20(6):667-70. PubMed ID: 546986
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Rational automatic search method for stable docking models of protein and ligand.
    Mizutani MY; Tomioka N; Itai A
    J Mol Biol; 1994 Oct; 243(2):310-26. PubMed ID: 7932757
    [TBL] [Abstract][Full Text] [Related]  

  • 35. A possible histochemical mechanism of dihydrofolate reductase reaction.
    Onicescu D; Taşcă L
    Morphol Embryol (Bucur); 1977; 23(2):103-6. PubMed ID: 16210
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate.
    Davies JF; Delcamp TJ; Prendergast NJ; Ashford VA; Freisheim JH; Kraut J
    Biochemistry; 1990 Oct; 29(40):9467-79. PubMed ID: 2248959
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Evolutionary Effects on Bound Substrate p K
    Mhashal AR; Pshetitsky Y; Cheatum CM; Kohen A; Major DT
    J Am Chem Soc; 2018 Dec; 140(48):16650-16660. PubMed ID: 30398861
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Effect of mutation on enzyme motion in dihydrofolate reductase.
    Watney JB; Agarwal PK; Hammes-Schiffer S
    J Am Chem Soc; 2003 Apr; 125(13):3745-50. PubMed ID: 12656604
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases--inhibition by folic acid and polyphenols.
    Kao TT; Wang KC; Chang WN; Lin CY; Chen BH; Wu HL; Shi GY; Tsai JN; Fu TF
    Drug Metab Dispos; 2008 Mar; 36(3):508-16. PubMed ID: 18056255
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular modeling study of dihydrofolate reductase inhibitors. Molecular dynamics simulations, quantum mechanical calculations, and experimental corroboration.
    Tosso RD; Andujar SA; Gutierrez L; Angelina E; Rodríguez R; Nogueras M; Baldoni H; Suvire FD; Cobo J; Enriz RD
    J Chem Inf Model; 2013 Aug; 53(8):2018-32. PubMed ID: 23834278
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.