BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 20061534)

  • 1. Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion.
    Leibiger B; Moede T; Uhles S; Barker CJ; Creveaux M; Domin J; Berggren PO; Leibiger IB
    FASEB J; 2010 Jun; 24(6):1824-37. PubMed ID: 20061534
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation.
    Leibiger B; Moede T; Paschen M; Yunn NO; Lim JH; Ryu SH; Pereira T; Berggren PO; Leibiger IB
    Cell Rep; 2015 Oct; 13(1):15-22. PubMed ID: 26387957
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Acute inhibition of PI3K-PDK1-Akt pathway potentiates insulin secretion through upregulation of newcomer granule fusions in pancreatic β-cells.
    Aoyagi K; Ohara-Imaizumi M; Nishiwaki C; Nakamichi Y; Ueki K; Kadowaki T; Nagamatsu S
    PLoS One; 2012; 7(10):e47381. PubMed ID: 23077605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway.
    Tsuchiya A; Kanno T; Nishizaki T
    J Endocrinol; 2014 Jan; 220(1):49-59. PubMed ID: 24169049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
    Jiang ZY; Zhou QL; Holik J; Patel S; Leszyk J; Coleman K; Chouinard M; Czech MP
    J Biol Chem; 2005 Jun; 280(22):21622-8. PubMed ID: 15799971
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The CC chemokine monocyte chemotactic peptide-1 activates both the class I p85/p110 phosphatidylinositol 3-kinase and the class II PI3K-C2alpha.
    Turner SJ; Domin J; Waterfield MD; Ward SG; Westwick J
    J Biol Chem; 1998 Oct; 273(40):25987-95. PubMed ID: 9748276
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cellular depletion of atypical PKC{lambda} is associated with enhanced insulin sensitivity and glucose uptake in L6 rat skeletal muscle cells.
    Stretton C; Evans A; Hundal HS
    Am J Physiol Endocrinol Metab; 2010 Sep; 299(3):E402-12. PubMed ID: 20530734
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of phosphoinositide 3-kinase C2alpha in insulin signaling.
    Falasca M; Hughes WE; Dominguez V; Sala G; Fostira F; Fang MQ; Cazzolli R; Shepherd PR; James DE; Maffucci T
    J Biol Chem; 2007 Sep; 282(38):28226-36. PubMed ID: 17644513
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The α-isoform of class II phosphoinositide 3-kinase is necessary for the activation of ERK but not Akt/PKB.
    Cui ZG; Hong NY; Kang HK; Lee DH; Lee YK; Park DB
    Mol Cell Biochem; 2011 Jan; 346(1-2):95-101. PubMed ID: 20924651
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells.
    Dominguez V; Raimondi C; Somanath S; Bugliani M; Loder MK; Edling CE; Divecha N; da Silva-Xavier G; Marselli L; Persaud SJ; Turner MD; Rutter GA; Marchetti P; Falasca M; Maffucci T
    J Biol Chem; 2011 Feb; 286(6):4216-25. PubMed ID: 21127054
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ca2+-regulated pool of phosphatidylinositol-3-phosphate produced by phosphatidylinositol 3-kinase C2alpha on neurosecretory vesicles.
    Wen PJ; Osborne SL; Morrow IC; Parton RG; Domin J; Meunier FA
    Mol Biol Cell; 2008 Dec; 19(12):5593-603. PubMed ID: 18843041
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Involvement of IGF-1 and MEOX2 in PI3K/Akt1/2 and ERK1/2 pathways mediated proliferation and differentiation of perivascular adipocytes.
    Liu P; Kong F; Wang J; Lu Q; Xu H; Qi T; Meng J
    Exp Cell Res; 2015 Feb; 331(1):82-96. PubMed ID: 25239227
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells.
    Biswas K; Yoshioka K; Asanuma K; Okamoto Y; Takuwa N; Sasaki T; Takuwa Y
    J Biol Chem; 2013 Jan; 288(4):2325-39. PubMed ID: 23192342
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sex differences in the mechanism of Met5-enkephalin-induced cardioprotection: role of PI3K/Akt.
    Cao Z; Liu L; Packwood W; Merkel M; Hurn PD; Van Winkle DM
    Am J Physiol Heart Circ Physiol; 2008 Jan; 294(1):H302-10. PubMed ID: 17982014
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Protective action of liraglutide in beta cells under lipotoxic stress via PI3K/Akt/FoxO1 pathway.
    Shao S; Nie M; Chen C; Chen X; Zhang M; Yuan G; Yu X; Yang Y
    J Cell Biochem; 2014 Jun; 115(6):1166-75. PubMed ID: 24415347
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.
    Okano J; Gaslightwala I; Birnbaum MJ; Rustgi AK; Nakagawa H
    J Biol Chem; 2000 Oct; 275(40):30934-42. PubMed ID: 10908564
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice.
    Alliouachene S; Bilanges B; Chaussade C; Pearce W; Foukas LC; Scudamore CL; Moniz LS; Vanhaesebroeck B
    Diabetologia; 2016 Jul; 59(7):1503-1512. PubMed ID: 27138914
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes.
    Zhu S; Sun F; Li W; Cao Y; Wang C; Wang Y; Liang D; Zhang R; Zhang S; Wang H; Cao F
    Mol Cell Biochem; 2011 Jul; 353(1-2):305-13. PubMed ID: 21461612
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation.
    Bartolomé A; Guillén C; Benito M
    Endocrinology; 2010 Jul; 151(7):3084-94. PubMed ID: 20427478
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells.
    Leibiger B; Leibiger IB; Moede T; Kemper S; Kulkarni RN; Kahn CR; de Vargas LM; Berggren PO
    Mol Cell; 2001 Mar; 7(3):559-70. PubMed ID: 11463381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.