These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
223 related articles for article (PubMed ID: 20064438)
1. Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites. Britton M; Lucas MM; Downey SL; Screen M; Pletnev AA; Verdoes M; Tokhunts RA; Amir O; Goddard AL; Pelphrey PM; Wright DL; Overkleeft HS; Kisselev AF Chem Biol; 2009 Dec; 16(12):1278-89. PubMed ID: 20064438 [TBL] [Abstract][Full Text] [Related]
2. Specific cell-permeable inhibitor of proteasome trypsin-like sites selectively sensitizes myeloma cells to bortezomib and carfilzomib. Mirabella AC; Pletnev AA; Downey SL; Florea BI; Shabaneh TB; Britton M; Verdoes M; Filippov DV; Overkleeft HS; Kisselev AF Chem Biol; 2011 May; 18(5):608-18. PubMed ID: 21609842 [TBL] [Abstract][Full Text] [Related]
3. Nature of pharmacophore influences active site specificity of proteasome inhibitors. Screen M; Britton M; Downey SL; Verdoes M; Voges MJ; Blom AE; Geurink PP; Risseeuw MD; Florea BI; van der Linden WA; Pletnev AA; Overkleeft HS; Kisselev AF J Biol Chem; 2010 Dec; 285(51):40125-34. PubMed ID: 20937826 [TBL] [Abstract][Full Text] [Related]
4. Importance of the different proteolytic sites of the proteasome and the efficacy of inhibitors varies with the protein substrate. Kisselev AF; Callard A; Goldberg AL J Biol Chem; 2006 Mar; 281(13):8582-90. PubMed ID: 16455650 [TBL] [Abstract][Full Text] [Related]
5. The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites. Kisselev AF; Garcia-Calvo M; Overkleeft HS; Peterson E; Pennington MW; Ploegh HL; Thornberry NA; Goldberg AL J Biol Chem; 2003 Sep; 278(38):35869-77. PubMed ID: 12815064 [TBL] [Abstract][Full Text] [Related]
6. A cell-permeable inhibitor and activity-based probe for the caspase-like activity of the proteasome. van Swieten PF; Samuel E; Hernández RO; van den Nieuwendijk AM; Leeuwenburgh MA; van der Marel GA; Kessler BM; Overkleeft HS; Kisselev AF Bioorg Med Chem Lett; 2007 Jun; 17(12):3402-5. PubMed ID: 17442566 [TBL] [Abstract][Full Text] [Related]
7. Development of novel peptidomimetics containing a vinyl sulfone moiety as proteasome inhibitors. Ettari R; Bonaccorso C; Micale N; Heindl C; Schirmeister T; Calabrò ML; Grasso S; Zappalà M ChemMedChem; 2011 Jul; 6(7):1228-37. PubMed ID: 21506279 [TBL] [Abstract][Full Text] [Related]
8. Incorporation of fluorinated phenylalanine generates highly specific inhibitor of proteasome's chymotrypsin-like sites. Geurink PP; Liu N; Spaans MP; Downey SL; van den Nieuwendijk AM; van der Marel GA; Kisselev AF; Florea BI; Overkleeft HS J Med Chem; 2010 Mar; 53(5):2319-23. PubMed ID: 20131905 [TBL] [Abstract][Full Text] [Related]
9. Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates. Kisselev AF; Goldberg AL Methods Enzymol; 2005; 398():364-78. PubMed ID: 16275343 [TBL] [Abstract][Full Text] [Related]
11. Inhibition of human and yeast 20S proteasome by analogues of trypsin inhibitor SFTI-1. Dębowski D; Pikuła M; Lubos M; Langa P; Trzonkowski P; Lesner A; Łęgowska A; Rolka K PLoS One; 2014; 9(2):e89465. PubMed ID: 24586798 [TBL] [Abstract][Full Text] [Related]
12. Proteasome active sites allosterically regulate each other, suggesting a cyclical bite-chew mechanism for protein breakdown. Kisselev AF; Akopian TN; Castillo V; Goldberg AL Mol Cell; 1999 Sep; 4(3):395-402. PubMed ID: 10518220 [TBL] [Abstract][Full Text] [Related]
13. [Proteasome inhibitors in cancer therapy]. Romaniuk W; Ołdziej AE; Zińczuk J; Kłoczko J Postepy Hig Med Dosw (Online); 2015 Dec; 69():1443-50. PubMed ID: 27259216 [TBL] [Abstract][Full Text] [Related]
14. Multicolor monitoring of the proteasome's catalytic signature. Priestman MA; Wang Q; Jernigan FE; Chowdhury R; Schmidt M; Lawrence DS ACS Chem Biol; 2015 Feb; 10(2):433-40. PubMed ID: 25347733 [TBL] [Abstract][Full Text] [Related]
15. Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome. Parlati F; Lee SJ; Aujay M; Suzuki E; Levitsky K; Lorens JB; Micklem DR; Ruurs P; Sylvain C; Lu Y; Shenk KD; Bennett MK Blood; 2009 Oct; 114(16):3439-47. PubMed ID: 19671918 [TBL] [Abstract][Full Text] [Related]
16. Activation of Chymotrypsin-Like Activity of the Proteasome during Ischemia Induces Myocardial Dysfunction and Death. Sanchez G; Berrios D; Olmedo I; Pezoa J; Riquelme JA; Montecinos L; Pedrozo Z; Donoso P PLoS One; 2016; 11(8):e0161068. PubMed ID: 27529620 [TBL] [Abstract][Full Text] [Related]
17. Proteasome-mediated degradation of tau proteins occurs independently of the chymotrypsin-like activity by a nonprocessive pathway. Cardozo C; Michaud C Arch Biochem Biophys; 2002 Dec; 408(1):103-10. PubMed ID: 12485608 [TBL] [Abstract][Full Text] [Related]
18. Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings. Kisselev AF; Kaganovich D; Goldberg AL J Biol Chem; 2002 Jun; 277(25):22260-70. PubMed ID: 11927581 [TBL] [Abstract][Full Text] [Related]
19. Apigenin, chrysin, and luteolin selectively inhibit chymotrypsin-like and trypsin-like proteasome catalytic activities in tumor cells. Wu YX; Fang X Planta Med; 2010 Feb; 76(2):128-32. PubMed ID: 19653143 [TBL] [Abstract][Full Text] [Related]
20. Proteasome inhibition correlates with intracellular bortezomib concentrations but not with antiproliferative effects after bolus treatment in myeloma cell lines. Dettmer S; Theile D; Schäfer J; Seckinger A; Burhenne J; Weiss J Naunyn Schmiedebergs Arch Pharmacol; 2016 Oct; 389(10):1091-101. PubMed ID: 27422413 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]