158 related articles for article (PubMed ID: 20065942)
1. Transgenic cardiac-targeted overexpression of human thymidylate kinase.
Kohler JJ; Hosseini SH; Cucoranu I; Zhelyabovska O; Green E; Ivey K; Abuin A; Fields E; Hoying A; Russ R; Santoianni R; Raper CM; Yang Q; Lavie A; Lewis W
Lab Invest; 2010 Mar; 90(3):383-90. PubMed ID: 20065942
[TBL] [Abstract][Full Text] [Related]
2. Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation.
Kohler JJ; Hosseini SH; Cucoranu I; Hoying-Brandt A; Green E; Johnson D; Wittich B; Srivastava J; Ivey K; Fields E; Russ R; Raper CM; Santoianni R; Lewis W
Lab Invest; 2009 Feb; 89(2):122-30. PubMed ID: 19079325
[TBL] [Abstract][Full Text] [Related]
3. Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy.
Kohler JJ; Cucoranu I; Fields E; Green E; He S; Hoying A; Russ R; Abuin A; Johnson D; Hosseini SH; Raper CM; Lewis W
Lab Invest; 2009 Jul; 89(7):782-90. PubMed ID: 19398959
[TBL] [Abstract][Full Text] [Related]
4. Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.
Lewis W; Kohler JJ; Hosseini SH; Haase CP; Copeland WC; Bienstock RJ; Ludaway T; McNaught J; Russ R; Stuart T; Santoianni R
AIDS; 2006 Mar; 20(5):675-84. PubMed ID: 16514297
[TBL] [Abstract][Full Text] [Related]
5. Pyrimidine deoxynucleoside and nucleoside reverse transcriptase inhibitor metabolism in the perfused heart and isolated mitochondria.
Morris GW; Laclair DD; McKee EE
Antivir Ther; 2010; 15(4):587-97. PubMed ID: 20587852
[TBL] [Abstract][Full Text] [Related]
6. In utero exposure of female CD-1 mice to AZT and/or 3TC: II. Persistence of functional alterations in cardiac tissue.
Torres SM; Divi RL; Walker DM; McCash CL; Carter MM; Campen MJ; Einem TL; Chu Y; Seilkop SK; Kang H; Poirier MC; Walker VE
Cardiovasc Toxicol; 2010 Jun; 10(2):87-99. PubMed ID: 20155331
[TBL] [Abstract][Full Text] [Related]
7. Transgenic mouse model with deficient mitochondrial polymerase exhibits reduced state IV respiration and enhanced cardiac fibrosis.
Koczor CA; Torres RA; Fields E; Qin Q; Park J; Ludaway T; Russ R; Lewis W
Lab Invest; 2013 Feb; 93(2):151-8. PubMed ID: 23090637
[TBL] [Abstract][Full Text] [Related]
8. Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals.
Hosseini SH; Kohler JJ; Haase CP; Tioleco N; Stuart T; Keebaugh E; Ludaway T; Russ R; Green E; Long R; Wang L; Eriksson S; Lewis W
Am J Pathol; 2007 Mar; 170(3):865-74. PubMed ID: 17322372
[TBL] [Abstract][Full Text] [Related]
9. Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line.
Prakash O; Tang ZY; Zhou P; Peng X; Kolls J; Shellito JE; Nelson S
Alcohol Clin Exp Res; 2002 Mar; 26(3):295-302. PubMed ID: 11923581
[TBL] [Abstract][Full Text] [Related]
10. Absence of mitochondrial toxicity in hearts of transgenic mice treated with abacavir.
Kohler JJ; Hosseini SH; Green E; Fields E; Abuin A; Ludaway T; Russ R; Lewis W
Cardiovasc Toxicol; 2010 Jun; 10(2):146-51. PubMed ID: 20379802
[TBL] [Abstract][Full Text] [Related]
11. Cardiac-targeted transgenic mutant mitochondrial enzymes: mtDNA defects, antiretroviral toxicity and cardiomyopathy.
Kohler JJ; Hosseini SH; Green E; Hoying-Brandt A; Cucoranu I; Haase CP; Russ R; Srivastava J; Ivey K; Ludaway T; Kapoor V; Abuin A; Shapoval A; Santoianni R; Saada A; Elpeleg O; Lewis W
Cardiovasc Toxicol; 2008; 8(2):57-69. PubMed ID: 18446447
[TBL] [Abstract][Full Text] [Related]
12. Restoration of the antiviral activity of 3'-azido-3'-deoxythymidine (AZT) against AZT-resistant human immunodeficiency virus by delivery of engineered thymidylate kinase to T cells.
Lavie A; Su Y; Ghassemi M; Novak RM; Caffrey M; Sekulic N; Monnerjahn C; Konrad M; Cook JL
J Gen Virol; 2008 Jul; 89(Pt 7):1672-1679. PubMed ID: 18559937
[TBL] [Abstract][Full Text] [Related]
13. Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Lavie A; Ostermann N; Brundiers R; Goody RS; Reinstein J; Konrad M; Schlichting I
Proc Natl Acad Sci U S A; 1998 Nov; 95(24):14045-50. PubMed ID: 9826650
[TBL] [Abstract][Full Text] [Related]
14. Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP.
Ostermann N; Lavie A; Padiyar S; Brundiers R; Veit T; Reinstein J; Goody RS; Konrad M; Schlichting I
J Mol Biol; 2000 Nov; 304(1):43-53. PubMed ID: 11071809
[TBL] [Abstract][Full Text] [Related]
15. Fetal patas monkeys sustain mitochondrial toxicity as a result of in utero zidovudine exposure.
Gerschenson M; Poirier MC
Ann N Y Acad Sci; 2000 Nov; 918():269-81. PubMed ID: 11131713
[TBL] [Abstract][Full Text] [Related]
16. Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity.
McKee EE; Bentley AT; Hatch M; Gingerich J; Susan-Resiga D
Cardiovasc Toxicol; 2004; 4(2):155-67. PubMed ID: 15371631
[TBL] [Abstract][Full Text] [Related]
17. Persistence of mitochondrial toxicity in hearts of female B6C3F1 mice exposed in utero to 3'-azido-3'-deoxythymidine.
Walker DM; Poirier MC; Campen MJ; Cook DL; Divi RL; Nagashima K; Lund AK; Cossey PY; Hahn FF; Walker VE
Cardiovasc Toxicol; 2004; 4(2):133-53. PubMed ID: 15371630
[TBL] [Abstract][Full Text] [Related]
18. In utero exposure of female CD-1 Mice to AZT and/or 3TC: I. Persistence of microscopic lesions in cardiac tissue.
Torres SM; March TH; Carter MM; McCash CL; Seilkop SK; Poirier MC; Walker DM; Walker VE
Cardiovasc Toxicol; 2010 Mar; 10(1):37-50. PubMed ID: 20101476
[TBL] [Abstract][Full Text] [Related]
19. Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase.
Lavie A; Konrad M
Mini Rev Med Chem; 2004 May; 4(4):351-9. PubMed ID: 15134538
[TBL] [Abstract][Full Text] [Related]
20. Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.
Chan SS; Santos JH; Meyer JN; Mandavilli BS; Cook DL; McCash CL; Kissling GE; Nyska A; Foley JF; van Houten B; Copeland WC; Walker VE; Witt KL; Bishop JB
Environ Mol Mutagen; 2007; 48(3-4):190-200. PubMed ID: 16395692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
