305 related articles for article (PubMed ID: 20068072)
1. Mechanisms of ascorbate-induced cytotoxicity in pancreatic cancer.
Du J; Martin SM; Levine M; Wagner BA; Buettner GR; Wang SH; Taghiyev AF; Du C; Knudson CM; Cullen JJ
Clin Cancer Res; 2010 Jan; 16(2):509-20. PubMed ID: 20068072
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological Ascorbate Radiosensitizes Pancreatic Cancer.
Du J; Cieslak JA; Welsh JL; Sibenaller ZA; Allen BG; Wagner BA; Kalen AL; Doskey CM; Strother RK; Button AM; Mott SL; Smith B; Tsai S; Mezhir J; Goswami PC; Spitz DR; Buettner GR; Cullen JJ
Cancer Res; 2015 Aug; 75(16):3314-26. PubMed ID: 26081808
[TBL] [Abstract][Full Text] [Related]
3. Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer.
Cieslak JA; Strother RK; Rawal M; Du J; Doskey CM; Schroeder SR; Button A; Wagner BA; Buettner GR; Cullen JJ
Free Radic Biol Med; 2015 Jun; 83():227-37. PubMed ID: 25725418
[TBL] [Abstract][Full Text] [Related]
4. Pharmacologic ascorbate (P-AscH
Wilkes JG; O'Leary BR; Du J; Klinger AR; Sibenaller ZA; Doskey CM; Gibson-Corley KN; Alexander MS; Tsai S; Buettner GR; Cullen JJ
Clin Exp Metastasis; 2018 Feb; 35(1-2):37-51. PubMed ID: 29396728
[TBL] [Abstract][Full Text] [Related]
5. Dual Oxidase-Induced Sustained Generation of Hydrogen Peroxide Contributes to Pharmacologic Ascorbate-Induced Cytotoxicity.
Gibson AR; O'Leary BR; Du J; Sarsour EH; Kalen AL; Wagner BA; Stolwijk JM; Falls-Hubert KC; Alexander MS; Carroll RS; Spitz DR; Buettner GR; Goswami PC; Cullen JJ
Cancer Res; 2020 Apr; 80(7):1401-1413. PubMed ID: 32041838
[TBL] [Abstract][Full Text] [Related]
6. JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice.
Song X; Zhu S; Xie Y; Liu J; Sun L; Zeng D; Wang P; Ma X; Kroemer G; Bartlett DL; Billiar TR; Lotze MT; Zeh HJ; Kang R; Tang D
Gastroenterology; 2018 Apr; 154(5):1480-1493. PubMed ID: 29248440
[TBL] [Abstract][Full Text] [Related]
7. Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer.
Alexander MS; Wilkes JG; Schroeder SR; Buettner GR; Wagner BA; Du J; Gibson-Corley K; O'Leary BR; Spitz DR; Buatti JM; Berg DJ; Bodeker KL; Vollstedt S; Brown HA; Allen BG; Cullen JJ
Cancer Res; 2018 Dec; 78(24):6838-6851. PubMed ID: 30254147
[TBL] [Abstract][Full Text] [Related]
8. Treatment of Pancreatic Cancer with Pharmacological Ascorbate.
Cieslak JA; Cullen JJ
Curr Pharm Biotechnol; 2015; 16(9):759-70. PubMed ID: 26201606
[TBL] [Abstract][Full Text] [Related]
9. Manganoporphyrins increase ascorbate-induced cytotoxicity by enhancing H2O2 generation.
Rawal M; Schroeder SR; Wagner BA; Cushing CM; Welsh JL; Button AM; Du J; Sibenaller ZA; Buettner GR; Cullen JJ
Cancer Res; 2013 Aug; 73(16):5232-41. PubMed ID: 23764544
[TBL] [Abstract][Full Text] [Related]
10. Anticancer therapeutic potential of Mn porphyrin/ascorbate system.
Tovmasyan A; Sampaio RS; Boss MK; Bueno-Janice JC; Bader BH; Thomas M; Reboucas JS; Orr M; Chandler JD; Go YM; Jones DP; Venkatraman TN; Haberle S; Kyui N; Lascola CD; Dewhirst MW; Spasojevic I; Benov L; Batinic-Haberle I
Free Radic Biol Med; 2015 Dec; 89():1231-47. PubMed ID: 26496207
[TBL] [Abstract][Full Text] [Related]
11. Pharmacological ascorbate inhibits pancreatic cancer metastases via a peroxide-mediated mechanism.
O'Leary BR; Alexander MS; Du J; Moose DL; Henry MD; Cullen JJ
Sci Rep; 2020 Oct; 10(1):17649. PubMed ID: 33077776
[TBL] [Abstract][Full Text] [Related]
12. Mechanism of Ascorbate-Induced Cell Death in Human Pancreatic Cancer Cells: Role of Bcl-2, Beclin 1 and Autophagy.
Fukui M; Yamabe N; Choi HJ; Polireddy K; Chen Q; Zhu BT
Planta Med; 2015 Jul; 81(10):838-46. PubMed ID: 26132849
[TBL] [Abstract][Full Text] [Related]
13. Pharmacologic Ascorbate Primes Pancreatic Cancer Cells for Death by Rewiring Cellular Energetics and Inducing DNA Damage.
Buranasudja V; Doskey CM; Gibson AR; Wagner BA; Du J; Gordon DJ; Koppenhafer SL; Cullen JJ; Buettner GR
Mol Cancer Res; 2019 Oct; 17(10):2102-2114. PubMed ID: 31337671
[TBL] [Abstract][Full Text] [Related]
14. Tumor cells have decreased ability to metabolize H
Doskey CM; Buranasudja V; Wagner BA; Wilkes JG; Du J; Cullen JJ; Buettner GR
Redox Biol; 2016 Dec; 10():274-284. PubMed ID: 27833040
[TBL] [Abstract][Full Text] [Related]
15. Inhibitors of hydroperoxide metabolism enhance ascorbate-induced cytotoxicity.
Olney KE; Du J; van 't Erve TJ; Witmer JR; Sibenaller ZA; Wagner BA; Buettner GR; Cullen JJ
Free Radic Res; 2013 Mar; 47(3):154-63. PubMed ID: 23205739
[TBL] [Abstract][Full Text] [Related]
16. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues.
Chen Q; Espey MG; Krishna MC; Mitchell JB; Corpe CP; Buettner GR; Shacter E; Levine M
Proc Natl Acad Sci U S A; 2005 Sep; 102(38):13604-9. PubMed ID: 16157892
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy.
Chen P; Yu J; Chalmers B; Drisko J; Yang J; Li B; Chen Q
Anticancer Drugs; 2012 Apr; 23(4):437-44. PubMed ID: 22205155
[TBL] [Abstract][Full Text] [Related]
18. Pharmacological Ascorbate as an Adjuvant for Enhancing Radiation-Chemotherapy Responses in Gastric Adenocarcinoma.
O'Leary BR; Houwen FK; Johnson CL; Allen BG; Mezhir JJ; Berg DJ; Cullen JJ; Spitz DR
Radiat Res; 2018 May; 189(5):456-465. PubMed ID: 29547353
[TBL] [Abstract][Full Text] [Related]
19. Effect of small interference RNA targeting HIF-1alpha mediated by rAAV combined L: -ascorbate on pancreatic tumors in athymic mice.
Chen C; Sun J; Liu G; Chen J
Pathol Oncol Res; 2009 Mar; 15(1):109-14. PubMed ID: 18509748
[TBL] [Abstract][Full Text] [Related]
20. Pharmacological ascorbate induces sustained mitochondrial dysfunction.
Carroll RS; Du J; O'Leary BR; Steers G; Goswami PC; Buettner GR; Cullen JJ
Free Radic Biol Med; 2023 Aug; 204():108-117. PubMed ID: 37137343
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
