147 related articles for article (PubMed ID: 20068078)
1. A CYP3A4 phenotype-based dosing algorithm for individualized treatment of irinotecan.
van der Bol JM; Mathijssen RH; Creemers GJ; Planting AS; Loos WJ; Wiemer EA; Friberg LE; Verweij J; Sparreboom A; de Jong FA
Clin Cancer Res; 2010 Jan; 16(2):736-42. PubMed ID: 20068078
[TBL] [Abstract][Full Text] [Related]
2. Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes.
Mathijssen RH; de Jong FA; van Schaik RH; Lepper ER; Friberg LE; Rietveld T; de Bruijn P; Graveland WJ; Figg WD; Verweij J; Sparreboom A
J Natl Cancer Inst; 2004 Nov; 96(21):1585-92. PubMed ID: 15523087
[TBL] [Abstract][Full Text] [Related]
3. Modulation of irinotecan metabolism by ketoconazole.
Kehrer DF; Mathijssen RH; Verweij J; de Bruijn P; Sparreboom A
J Clin Oncol; 2002 Jul; 20(14):3122-9. PubMed ID: 12118026
[TBL] [Abstract][Full Text] [Related]
4. Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.
Sai K; Saito Y; Fukushima-Uesaka H; Kurose K; Kaniwa N; Kamatani N; Shirao K; Yamamoto N; Hamaguchi T; Kunitoh H; Ohe Y; Tamura T; Yamada Y; Minami H; Ohtsu A; Yoshida T; Saijo N; Sawada J
Cancer Chemother Pharmacol; 2008 Aug; 62(3):529-37. PubMed ID: 17992531
[TBL] [Abstract][Full Text] [Related]
5. Effect of milk thistle (Silybum marianum) on the pharmacokinetics of irinotecan.
van Erp NP; Baker SD; Zhao M; Rudek MA; Guchelaar HJ; Nortier JW; Sparreboom A; Gelderblom H
Clin Cancer Res; 2005 Nov; 11(21):7800-6. PubMed ID: 16278402
[TBL] [Abstract][Full Text] [Related]
6. Phenotyping of UGT1A1 Activity Using Raltegravir Predicts Pharmacokinetics and Toxicity of Irinotecan in FOLFIRI.
Lee LS; Seng KY; Wang LZ; Yong WP; Hee KH; Soh TI; Wong A; Cheong PF; Soong R; Sapari NS; Soo R; Fan L; Lee SC; Goh BC
PLoS One; 2016; 11(1):e0147681. PubMed ID: 26808671
[TBL] [Abstract][Full Text] [Related]
7. Phase I pharmacokinetic, food effect, and pharmacogenetic study of oral irinotecan given as semisolid matrix capsules in patients with solid tumors.
Soepenberg O; Dumez H; Verweij J; de Jong FA; de Jonge MJ; Thomas J; Eskens FA; van Schaik RH; Selleslach J; Ter Steeg J; Lefebvre P; Assadourian S; Sanderink GJ; Sparreboom A; van Oosterom AT
Clin Cancer Res; 2005 Feb; 11(4):1504-11. PubMed ID: 15746053
[TBL] [Abstract][Full Text] [Related]
8. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics.
Innocenti F; Kroetz DL; Schuetz E; Dolan ME; Ramírez J; Relling M; Chen P; Das S; Rosner GL; Ratain MJ
J Clin Oncol; 2009 Jun; 27(16):2604-14. PubMed ID: 19349540
[TBL] [Abstract][Full Text] [Related]
9. UGT1A1 promoter genotype correlates with SN-38 pharmacokinetics, but not severe toxicity in patients receiving low-dose irinotecan.
Stewart CF; Panetta JC; O'Shaughnessy MA; Throm SL; Fraga CH; Owens T; Liu T; Billups C; Rodriguez-Galindo C; Gajjar A; Furman WL; McGregor LM
J Clin Oncol; 2007 Jun; 25(18):2594-600. PubMed ID: 17577039
[TBL] [Abstract][Full Text] [Related]
10. Sequence effect of irinotecan and fluorouracil treatment on pharmacokinetics and toxicity in chemotherapy-naive metastatic colorectal cancer patients.
Falcone A; Di Paolo A; Masi G; Allegrini G; Danesi R; Lencioni M; Pfanner E; Comis S; Del Tacca M; Conte P
J Clin Oncol; 2001 Aug; 19(15):3456-62. PubMed ID: 11481350
[TBL] [Abstract][Full Text] [Related]
11. UGT1A1*28 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma.
Liu CY; Chen PM; Chiou TJ; Liu JH; Lin JK; Lin TC; Chen WS; Jiang JK; Wang HS; Wang WS
Cancer; 2008 May; 112(9):1932-40. PubMed ID: 18300238
[TBL] [Abstract][Full Text] [Related]
12. Individualizing dosing of irinotecan.
Ratain MJ; Innocenti F
Clin Cancer Res; 2010 Jan; 16(2):371-2. PubMed ID: 20068075
[TBL] [Abstract][Full Text] [Related]
13. A UGT1A1*28 and *6 genotype-directed phase I dose-escalation trial of irinotecan with fixed-dose capecitabine in Korean patients with metastatic colorectal cancer.
Kim KP; Kim HS; Sym SJ; Bae KS; Hong YS; Chang HM; Lee JL; Kang YK; Lee JS; Shin JG; Kim TW
Cancer Chemother Pharmacol; 2013 Jun; 71(6):1609-17. PubMed ID: 23595344
[TBL] [Abstract][Full Text] [Related]
14. Irinotecan, a key chemotherapeutic drug for metastatic colorectal cancer.
Fujita K; Kubota Y; Ishida H; Sasaki Y
World J Gastroenterol; 2015 Nov; 21(43):12234-48. PubMed ID: 26604633
[TBL] [Abstract][Full Text] [Related]
15. Irinotecan pharmacokinetics-pharmacodynamics: the clinical relevance of prolonged exposure to SN-38.
Mathijssen RH; Verweij J; Loos WJ; de Bruijn P; Nooter K; Sparreboom A
Br J Cancer; 2002 Jul; 87(2):144-50. PubMed ID: 12107833
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of UGT1A1 and CYP3A Genotyping and Single-Point Irinotecan and Metabolite Concentrations as Predictors of the Occurrence of Adverse Events in Cancer Treatment.
Basso J; Schwartsmann G; Ibaldi MR; Schaefer VD; Pavei CC; Hahn RZ; Antunes MV; Linden R
J Gastrointest Cancer; 2023 Jun; 54(2):589-599. PubMed ID: 35710870
[TBL] [Abstract][Full Text] [Related]
17. Genotype-directed, dose-finding study of irinotecan in cancer patients with UGT1A1*28 and/or UGT1A1*6 polymorphisms.
Satoh T; Ura T; Yamada Y; Yamazaki K; Tsujinaka T; Munakata M; Nishina T; Okamura S; Esaki T; Sasaki Y; Koizumi W; Kakeji Y; Ishizuka N; Hyodo I; Sakata Y
Cancer Sci; 2011 Oct; 102(10):1868-73. PubMed ID: 21740478
[TBL] [Abstract][Full Text] [Related]
18. Relevance of CYP3A4*20, UGT1A1*37 and UGT1A1*28 variants in irinotecan-induced severe toxicity.
Riera P; Salazar J; Virgili AC; Tobeña M; Sebio A; Gallano P; Barnadas A; Páez D
Br J Clin Pharmacol; 2018 Jun; 84(6):1389-1392. PubMed ID: 29504153
[TBL] [Abstract][Full Text] [Related]
19. Clinical and pharmacogenetic factors associated with irinotecan toxicity.
Kweekel D; Guchelaar HJ; Gelderblom H
Cancer Treat Rev; 2008 Nov; 34(7):656-69. PubMed ID: 18558463
[TBL] [Abstract][Full Text] [Related]
20. Population pharmacokinetic model of irinotecan and its metabolites in patients with metastatic colorectal cancer.
Oyaga-Iriarte E; Insausti A; Sayar O; Aldaz A
Eur J Clin Pharmacol; 2019 Apr; 75(4):529-542. PubMed ID: 30610273
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
