BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 20069570)

  • 21. Palmitate-Induced Insulin Hypersecretion and Later Secretory Decline Associated with Changes in Protein Expression Patterns in Human Pancreatic Islets.
    Groebe K; Cen J; Schvartz D; Sargsyan E; Chowdhury A; Roomp K; Schneider R; Alderborn A; Sanchez JC; Bergsten P
    J Proteome Res; 2018 Nov; 17(11):3824-3836. PubMed ID: 30183308
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Long-Term Exposure of Pancreatic β-Cells to Palmitate Results in SREBP-1C-Dependent Decreases in GLP-1 Receptor Signaling via CREB and AKT and Insulin Secretory Response.
    Natalicchio A; Biondi G; Marrano N; Labarbuta R; Tortosa F; Spagnuolo R; D'Oria R; Carchia E; Leonardini A; Cignarelli A; Perrini S; Laviola L; Giorgino F
    Endocrinology; 2016 Jun; 157(6):2243-58. PubMed ID: 27035653
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle.
    Zhou YP; Grill VE
    J Clin Invest; 1994 Feb; 93(2):870-6. PubMed ID: 8113418
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Increasing triglyceride synthesis inhibits glucose-induced insulin secretion in isolated rat islets of langerhans: a study using adenoviral expression of diacylglycerol acyltransferase.
    Kelpe CL; Johnson LM; Poitout V
    Endocrinology; 2002 Sep; 143(9):3326-32. PubMed ID: 12193544
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Effects of pharmacological inhibition of NADPH oxidase or iNOS on pro-inflammatory cytokine, palmitic acid or H2O2-induced mouse islet or clonal pancreatic β-cell dysfunction.
    Michalska M; Wolf G; Walther R; Newsholme P
    Biosci Rep; 2010 Dec; 30(6):445-53. PubMed ID: 20178457
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Long-Term exposure of INS-1 cells to cis and trans fatty acids influences insulin release and fatty acid oxidation differentially.
    Alstrup KK; Brock B; Hermansen K
    Metabolism; 2004 Sep; 53(9):1158-65. PubMed ID: 15334378
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Adiponectin increases glucose-induced insulin secretion through the activation of lipid oxidation.
    Patané G; Caporarello N; Marchetti P; Parrino C; Sudano D; Marselli L; Vigneri R; Frittitta L
    Acta Diabetol; 2013 Dec; 50(6):851-7. PubMed ID: 23440352
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells.
    Watson ML; Macrae K; Marley AE; Hundal HS
    PLoS One; 2011; 6(10):e25975. PubMed ID: 21998735
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Enhanced mitochondrial metabolism may account for the adaptation to insulin resistance in islets from C57BL/6J mice fed a high-fat diet.
    Fex M; Nitert MD; Wierup N; Sundler F; Ling C; Mulder H
    Diabetologia; 2007 Jan; 50(1):74-83. PubMed ID: 17093947
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Oleate rescues INS-1E β-cells from palmitate-induced apoptosis by preventing activation of the unfolded protein response.
    Sommerweiss D; Gorski T; Richter S; Garten A; Kiess W
    Biochem Biophys Res Commun; 2013 Nov; 441(4):770-6. PubMed ID: 24189472
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Lipotoxicity of the pancreatic beta-cell is associated with glucose-dependent esterification of fatty acids into neutral lipids.
    Briaud I; Harmon JS; Kelpe CL; Segu VB; Poitout V
    Diabetes; 2001 Feb; 50(2):315-21. PubMed ID: 11272142
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism.
    Roomp K; Kristinsson H; Schvartz D; Ubhayasekera K; Sargsyan E; Manukyan L; Chowdhury A; Manell H; Satagopam V; Groebe K; Schneider R; Bergquist J; Sanchez JC; Bergsten P
    PLoS One; 2017; 12(4):e0176391. PubMed ID: 28448538
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Long-term exposure to glucose and lipids inhibits glucose-induced insulin secretion downstream of granule fusion with plasma membrane.
    Olofsson CS; Collins S; Bengtsson M; Eliasson L; Salehi A; Shimomura K; Tarasov A; Holm C; Ashcroft F; Rorsman P
    Diabetes; 2007 Jul; 56(7):1888-97. PubMed ID: 17456851
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Acute and chronic effects of different concentrations of free fatty acids on the insulin secreting function of islets.
    Ayvaz G; Balos Törüner F; Karakoç A; Yetkin I; Cakir N; Arslan M
    Diabetes Metab; 2002 Dec; 28(6 Pt 2):3S7-12; discussion 3S108-12. PubMed ID: 12688627
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets.
    da Silva Krause M; Bittencourt A; Homem de Bittencourt PI; McClenaghan NH; Flatt PR; Murphy C; Newsholme P
    J Endocrinol; 2012 Sep; 214(3):301-11. PubMed ID: 22761278
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Inhibition of Monoacylglycerol Lipase Activity Decreases Glucose-Stimulated Insulin Secretion in INS-1 (832/13) Cells and Rat Islets.
    Berdan CA; Erion KA; Burritt NE; Corkey BE; Deeney JT
    PLoS One; 2016; 11(2):e0149008. PubMed ID: 26867016
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Fatty acids rapidly induce the carnitine palmitoyltransferase I gene in the pancreatic beta-cell line INS-1.
    Assimacopoulos-Jeannet F; Thumelin S; Roche E; Esser V; McGarry JD; Prentki M
    J Biol Chem; 1997 Jan; 272(3):1659-64. PubMed ID: 8999842
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Short-term inhibition of autophagy benefits pancreatic β-cells by augmenting ether lipids and peroxisomal function, and by countering depletion of n-3 polyunsaturated fatty acids after fat-feeding.
    Chu KY; Mellet N; Thai LM; Meikle PJ; Biden TJ
    Mol Metab; 2020 Oct; 40():101023. PubMed ID: 32504884
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The impairment of glucose-stimulated insulin secretion in pancreatic β-cells caused by prolonged glucotoxicity and lipotoxicity is associated with elevated adaptive antioxidant response.
    Fu J; Cui Q; Yang B; Hou Y; Wang H; Xu Y; Wang D; Zhang Q; Pi J
    Food Chem Toxicol; 2017 Feb; 100():161-167. PubMed ID: 28027979
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of cholinergic potentiation of insulin secretion from pancreatic islets by chronic elevation of glucose and fatty acids: Protection by casein kinase 2 inhibitor.
    Doliba NM; Liu Q; Li C; Chen P; Liu C; Naji A; Matschinsky FM
    Mol Metab; 2017 Oct; 6(10):1240-1253. PubMed ID: 29031723
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.