BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

257 related articles for article (PubMed ID: 20072153)

  • 1. Histone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.
    Leclerc GJ; Mou C; Leclerc GM; Mian AM; Barredo JC
    Leukemia; 2010 Mar; 24(3):552-62. PubMed ID: 20072153
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differences in folylpolyglutamate synthetase and dihydrofolate reductase expression in human B-lineage versus T-lineage leukemic lymphoblasts: mechanisms for lineage differences in methotrexate polyglutamylation and cytotoxicity.
    Galpin AJ; Schuetz JD; Masson E; Yanishevski Y; Synold TW; Barredo JC; Pui CH; Relling MV; Evans WE
    Mol Pharmacol; 1997 Jul; 52(1):155-63. PubMed ID: 9224825
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
    Liani E; Rothem L; Bunni MA; Smith CA; Jansen G; Assaraf YG
    Int J Cancer; 2003 Feb; 103(5):587-99. PubMed ID: 12494465
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Glutamic Acid Increased Methotrexate Polyglutamation and Cytotoxicity in a CCRF-SB Acute Lymphoblastic Leukemia Cell Line.
    Mendoza-Santiago A; Becerra E; Garay E; Bah M; Berumen-Segura L; Escobar-Cabrera J; Hernández-Pérez A; García-Alcocer G
    Medicina (Kaunas); 2019 Nov; 55(12):. PubMed ID: 31779260
    [No Abstract]   [Full Text] [Related]  

  • 5. gamma-Glutamyl hydrolase and folylpolyglutamate synthetase activities predict polyglutamylation of methotrexate in acute leukemias.
    Longo GS; Gorlick R; Tong WP; Lin S; Steinherz P; Bertino JR
    Oncol Res; 1997; 9(5):259-63. PubMed ID: 9306433
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia.
    Wojtuszkiewicz A; Peters GJ; van Woerden NL; Dubbelman B; Escherich G; Schmiegelow K; Sonneveld E; Pieters R; van de Ven PM; Jansen G; Assaraf YG; Kaspers GJ; Cloos J
    J Hematol Oncol; 2015 May; 8():61. PubMed ID: 26022503
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of folylpoly-gamma-glutamate synthetase gene expression in human B-precursor ALL and T-lineage ALL cells.
    Leclerc GJ; Leclerc GM; Kinser TT; Barredo JC
    BMC Cancer; 2006 May; 6():132. PubMed ID: 16707018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effects of germline DHFR and FPGS variants on methotrexate metabolism and relapse of leukemia.
    Tulstrup M; Moriyama T; Jiang C; Grosjean M; Nersting J; Abrahamsson J; Grell K; Hjalgrim LL; Jónsson ÓG; Kanerva J; Lund B; Nielsen SN; Nielsen RL; Overgaard U; Quist-Paulsen P; Pruunsild K; Vaitkeviciene G; Wolthers BO; Zhang H; Gupta R; Yang JJ; Schmiegelow K
    Blood; 2020 Sep; 136(10):1161-1168. PubMed ID: 32391884
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A mathematical model of in vivo methotrexate accumulation in acute lymphoblastic leukemia.
    Panetta JC; Yanishevski Y; Pui CH; Sandlund JT; Rubnitz J; Rivera GK; Ribeiro R; Evans WE; Relling MV
    Cancer Chemother Pharmacol; 2002 Nov; 50(5):419-28. PubMed ID: 12439601
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.
    Barredo JC; Synold TW; Laver J; Relling MV; Pui CH; Priest DG; Evans WE
    Blood; 1994 Jul; 84(2):564-9. PubMed ID: 7517720
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Intrinsic resistance of cervical squamous cell carcinoma cell lines to methotrexate (MTX) as a result of decreased accumulation of intracellular MTX polyglutamates.
    Barakat RR; Li WW; Lovelace C; Bertino JR
    Gynecol Oncol; 1993 Oct; 51(1):54-60. PubMed ID: 7694891
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Decreased polyglutamylation of methotrexate in acute lymphoblastic leukemia blasts in adults compared to children with this disease.
    Göker E; Lin JT; Trippett T; Elisseyeff Y; Tong WP; Niedzwiecki D; Tan C; Steinherz P; Schweitzer BI; Bertino JR
    Leukemia; 1993 Jul; 7(7):1000-4. PubMed ID: 7686600
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modeling mechanisms of in vivo variability in methotrexate accumulation and folate pathway inhibition in acute lymphoblastic leukemia cells.
    Panetta JC; Sparreboom A; Pui CH; Relling MV; Evans WE
    PLoS Comput Biol; 2010 Dec; 6(12):e1001019. PubMed ID: 21152005
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression.
    Noro R; Miyanaga A; Minegishi Y; Okano T; Seike M; Soeno C; Kataoka K; Matsuda K; Yoshimura A; Gemma A
    Cancer Sci; 2010 Jun; 101(6):1424-30. PubMed ID: 20384633
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of folylpolyglutamate synthetase modulation on chemosensitivity of colon cancer cells to 5-fluorouracil and methotrexate.
    Sohn KJ; Smirnakis F; Moskovitz DN; Novakovic P; Yates Z; Lucock M; Croxford R; Kim YI
    Gut; 2004 Dec; 53(12):1825-31. PubMed ID: 15542523
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of methotrexate polyglutamates on thioguanine nucleotide concentrations during continuation therapy of acute lymphoblastic leukemia with mercaptopurine.
    Dervieux T; Hancock M; Evans W; Pui CH; Relling MV
    Leukemia; 2002 Feb; 16(2):209-12. PubMed ID: 11840287
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Intracellular pharmacokinetics of methotrexate polyglutamates in human breast cancer cells. Selective retention and less dissociable binding of 4-NH2-10-CH3-pteroylglutamate4 and 4-NH2-10-CH3-pteroylglutamate5 to dihydrofolate reductase.
    Jolivet J; Chabner BA
    J Clin Invest; 1983 Sep; 72(3):773-8. PubMed ID: 6193143
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia.
    Stark M; Wichman C; Avivi I; Assaraf YG
    Blood; 2009 Apr; 113(18):4362-9. PubMed ID: 19131550
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ex vivo resistance in childhood acute lymphoblastic leukemia: Correlations between BCRP, MRP1, MRP4 and MRP5 ABC transporter expression and intracellular methotrexate polyglutamate accumulation.
    Jaramillo AC; Cloos J; Lemos C; Stam RW; Kaspers GJL; Jansen G; Peters GJ
    Leuk Res; 2019 Apr; 79():45-51. PubMed ID: 30849662
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Reduced folate carrier expression in acute lymphoblastic leukemia: a mechanism for ploidy but not lineage differences in methotrexate accumulation.
    Belkov VM; Krynetski EY; Schuetz JD; Yanishevski Y; Masson E; Mathew S; Raimondi S; Pui CH; Relling MV; Evans WE
    Blood; 1999 Mar; 93(5):1643-50. PubMed ID: 10029593
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.