BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

236 related articles for article (PubMed ID: 20077113)

  • 21. Separate domains in GCN1 for binding protein kinase GCN2 and ribosomes are required for GCN2 activation in amino acid-starved cells.
    Sattlegger E; Hinnebusch AG
    EMBO J; 2000 Dec; 19(23):6622-33. PubMed ID: 11101534
    [TBL] [Abstract][Full Text] [Related]  

  • 22. A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2.
    Gárriz A; Qiu H; Dey M; Seo EJ; Dever TE; Hinnebusch AG
    Mol Cell Biol; 2009 Mar; 29(6):1592-607. PubMed ID: 19114556
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions.
    Van Dyke N; Baby J; Van Dyke MW
    J Mol Biol; 2006 May; 358(4):1023-31. PubMed ID: 16580682
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases.
    Cardin E; Latreille M; Khoury C; Greenwood MT; Larose L
    FEBS J; 2007 Nov; 274(22):5865-75. PubMed ID: 17944934
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Interaction between the tRNA-binding and C-terminal domains of Yeast Gcn2 regulates kinase activity in vivo.
    Lageix S; Zhang J; Rothenburg S; Hinnebusch AG
    PLoS Genet; 2015 Feb; 11(2):e1004991. PubMed ID: 25695491
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation.
    Visweswaraiah J; Lee SJ; Hinnebusch AG; Sattlegger E
    J Biol Chem; 2012 Nov; 287(45):37757-68. PubMed ID: 22888004
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Differential requirements for P stalk components in activating yeast protein kinase Gcn2 by stalled ribosomes during stress.
    Gupta R; Hinnebusch AG
    Proc Natl Acad Sci U S A; 2023 Apr; 120(16):e2300521120. PubMed ID: 37043534
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Global phosphoproteomics pinpoints uncharted Gcn2-mediated mechanisms of translational control.
    Dokládal L; Stumpe M; Pillet B; Hu Z; Garcia Osuna GM; Kressler D; Dengjel J; De Virgilio C
    Mol Cell; 2021 May; 81(9):1879-1889.e6. PubMed ID: 33743194
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Association of GCN1-GCN20 regulatory complex with the N-terminus of eIF2alpha kinase GCN2 is required for GCN2 activation.
    Garcia-Barrio M; Dong J; Ufano S; Hinnebusch AG
    EMBO J; 2000 Apr; 19(8):1887-99. PubMed ID: 10775272
    [TBL] [Abstract][Full Text] [Related]  

  • 30. The MAP kinase-activated protein kinase Rck2p plays a role in rapamycin sensitivity in Saccharomyces cerevisiae and Candida albicans.
    Li X; Huang X; Zhao J; Zhao J; Wei Y; Jiang L
    FEMS Yeast Res; 2008 Aug; 8(5):715-24. PubMed ID: 18625027
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae.
    Dilova I; Powers T
    FEMS Yeast Res; 2006 Jan; 6(1):112-9. PubMed ID: 16423076
    [TBL] [Abstract][Full Text] [Related]  

  • 32. GCN1, a translational activator of GCN4 in Saccharomyces cerevisiae, is required for phosphorylation of eukaryotic translation initiation factor 2 by protein kinase GCN2.
    Marton MJ; Crouch D; Hinnebusch AG
    Mol Cell Biol; 1993 Jun; 13(6):3541-56. PubMed ID: 8497269
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Global translational repression induced by iron deficiency in yeast depends on the Gcn2/eIF2α pathway.
    Romero AM; Ramos-Alonso L; Alepuz P; Puig S; Martínez-Pastor MT
    Sci Rep; 2020 Jan; 10(1):233. PubMed ID: 31937829
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Serine 577 is phosphorylated and negatively affects the tRNA binding and eIF2alpha kinase activities of GCN2.
    Garcia-Barrio M; Dong J; Cherkasova VA; Zhang X; Zhang F; Ufano S; Lai R; Qin J; Hinnebusch AG
    J Biol Chem; 2002 Aug; 277(34):30675-83. PubMed ID: 12070158
    [TBL] [Abstract][Full Text] [Related]  

  • 35. YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed.
    Sattlegger E; Swanson MJ; Ashcraft EA; Jennings JL; Fekete RA; Link AJ; Hinnebusch AG
    J Biol Chem; 2004 Jul; 279(29):29952-62. PubMed ID: 15126500
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Translation elongation factor 1A mutants with altered actin bundling activity show reduced aminoacyl-tRNA binding and alter initiation via eIF2α phosphorylation.
    Perez WB; Kinzy TG
    J Biol Chem; 2014 Jul; 289(30):20928-38. PubMed ID: 24936063
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling.
    Xiao L; Kamau E; Donze D; Grove A
    Gene; 2011 Dec; 489(1):55-62. PubMed ID: 21924331
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Snf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4.
    Cherkasova V; Qiu H; Hinnebusch AG
    Mol Cell Biol; 2010 Jun; 30(12):2862-73. PubMed ID: 20404097
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cells.
    Lageix S; Rothenburg S; Dever TE; Hinnebusch AG
    PLoS Genet; 2014 May; 10(5):e1004326. PubMed ID: 24811037
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids.
    Wek SA; Zhu S; Wek RC
    Mol Cell Biol; 1995 Aug; 15(8):4497-506. PubMed ID: 7623840
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.