These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

457 related articles for article (PubMed ID: 20080206)

  • 1. Oligomerization conditions Mdm2-mediated efficient p53 polyubiquitylation but not its proteasomal degradation.
    Hjerpe R; Aillet F; Lopitz-Otsoa F; Lang V; Torres-Ramos M; Farrás R; Hay RT; Rodríguez MS
    Int J Biochem Cell Biol; 2010 May; 42(5):725-35. PubMed ID: 20080206
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of Mdm2 and MdmX fusion proteins alters p53 mediated transactivation, ubiquitination, and degradation.
    Ghosh M; Huang K; Berberich SJ
    Biochemistry; 2003 Mar; 42(8):2291-9. PubMed ID: 12600196
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The degradation of p53 and its major E3 ligase Mdm2 is differentially dependent on the proteasomal ubiquitin receptor S5a.
    Sparks A; Dayal S; Das J; Robertson P; Menendez S; Saville MK
    Oncogene; 2014 Sep; 33(38):4685-96. PubMed ID: 24121268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tetramerization-defects of p53 result in aberrant ubiquitylation and transcriptional activity.
    Lang V; Pallara C; Zabala A; Lobato-Gil S; Lopitz-Otsoa F; Farrás R; Hjerpe R; Torres-Ramos M; Zabaleta L; Blattner C; Hay RT; Barrio R; Carracedo A; Fernandez-Recio J; Rodríguez MS; Aillet F
    Mol Oncol; 2014 Jul; 8(5):1026-42. PubMed ID: 24816189
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2.
    Davis JR; Mossalam M; Lim CS
    Mol Pharm; 2013 Apr; 10(4):1340-9. PubMed ID: 23398638
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p53 Ubiquitination and proteasomal degradation.
    Love IM; Shi D; Grossman SR
    Methods Mol Biol; 2013; 962():63-73. PubMed ID: 23150437
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mdm2 facilitates the association of p53 with the proteasome.
    Kulikov R; Letienne J; Kaur M; Grossman SR; Arts J; Blattner C
    Proc Natl Acad Sci U S A; 2010 Jun; 107(22):10038-43. PubMed ID: 20479273
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2.
    Joo HM; Kim JY; Jeong JB; Seong KM; Nam SY; Yang KH; Kim CS; Kim HS; Jeong M; An S; Jin YW
    Eur J Cell Biol; 2011 May; 90(5):420-31. PubMed ID: 21333377
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FKBP25, a novel regulator of the p53 pathway, induces the degradation of MDM2 and activation of p53.
    Ochocka AM; Kampanis P; Nicol S; Allende-Vega N; Cox M; Marcar L; Milne D; Fuller-Pace F; Meek D
    FEBS Lett; 2009 Feb; 583(4):621-6. PubMed ID: 19166840
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers.
    Katz C; Low-Calle AM; Choe JH; Laptenko O; Tong D; Joseph-Chowdhury JN; Garofalo F; Zhu Y; Friedler A; Prives C
    Genes Dev; 2018 Mar; 32(5-6):430-447. PubMed ID: 29549180
    [TBL] [Abstract][Full Text] [Related]  

  • 12. C-terminal modifications regulate MDM2 dissociation and nuclear export of p53.
    Carter S; Bischof O; Dejean A; Vousden KH
    Nat Cell Biol; 2007 Apr; 9(4):428-35. PubMed ID: 17369817
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cocompartmentalization of p53 and Mdm2 is a major determinant for Mdm2-mediated degradation of p53.
    Xirodimas DP; Stephen CW; Lane DP
    Exp Cell Res; 2001 Oct; 270(1):66-77. PubMed ID: 11597128
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TRIAD1 inhibits MDM2-mediated p53 ubiquitination and degradation.
    Bae S; Jung JH; Kim K; An IS; Kim SY; Lee JH; Park IC; Jin YW; Lee SJ; An S
    FEBS Lett; 2012 Sep; 586(19):3057-63. PubMed ID: 22819825
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Modulation of p53 degradation via MDM2-mediated ubiquitylation and the ubiquitin-proteasome system during reperfusion after stroke: role of oxidative stress.
    Saito A; Hayashi T; Okuno S; Nishi T; Chan PH
    J Cereb Blood Flow Metab; 2005 Feb; 25(2):267-80. PubMed ID: 15678128
    [TBL] [Abstract][Full Text] [Related]  

  • 16. MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24.
    Yamauchi T; Nishiyama M; Moroishi T; Yumimoto K; Nakayama KI
    Mol Cell Biol; 2014 Sep; 34(17):3321-40. PubMed ID: 24980433
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response.
    Lim KH; Park JJ; Gu BH; Kim JO; Park SG; Baek KH
    Sci Rep; 2015 Aug; 5():12793. PubMed ID: 26238070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation.
    Rodriguez MS; Desterro JM; Lain S; Lane DP; Hay RT
    Mol Cell Biol; 2000 Nov; 20(22):8458-67. PubMed ID: 11046142
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26.
    Ofir-Rosenfeld Y; Boggs K; Michael D; Kastan MB; Oren M
    Mol Cell; 2008 Oct; 32(2):180-9. PubMed ID: 18951086
    [TBL] [Abstract][Full Text] [Related]  

  • 20. MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation.
    Sasaki M; Nie L; Maki CG
    J Biol Chem; 2007 May; 282(19):14626-34. PubMed ID: 17363365
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.