244 related articles for article (PubMed ID: 20080592)
1. A mouse model of osteochondromagenesis from clonal inactivation of Ext1 in chondrocytes.
Jones KB; Piombo V; Searby C; Kurriger G; Yang B; Grabellus F; Roughley PJ; Morcuende JA; Buckwalter JA; Capecchi MR; Vortkamp A; Sheffield VC
Proc Natl Acad Sci U S A; 2010 Feb; 107(5):2054-9. PubMed ID: 20080592
[TBL] [Abstract][Full Text] [Related]
2. A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
Matsumoto K; Irie F; Mackem S; Yamaguchi Y
Proc Natl Acad Sci U S A; 2010 Jun; 107(24):10932-7. PubMed ID: 20534475
[TBL] [Abstract][Full Text] [Related]
3. Signaling systems affecting the severity of multiple osteochondromas.
Piombo V; Jochmann K; Hoffmann D; Wuelling M; Vortkamp A
Bone; 2018 Jun; 111():71-81. PubMed ID: 29545125
[TBL] [Abstract][Full Text] [Related]
4. Toward an understanding of the short bone phenotype associated with multiple osteochondromas.
Jones KB; Datar M; Ravichandran S; Jin H; Jurrus E; Whitaker R; Capecchi MR
J Orthop Res; 2013 Apr; 31(4):651-7. PubMed ID: 23192691
[TBL] [Abstract][Full Text] [Related]
5. Diminished levels of the putative tumor suppressor proteins EXT1 and EXT2 in exostosis chondrocytes.
Bernard MA; Hall CE; Hogue DA; Cole WG; Scott A; Snuggs MB; Clines GA; Lüdecke HJ; Lovett M; Van Winkle WB; Hecht JT
Cell Motil Cytoskeleton; 2001 Feb; 48(2):149-62. PubMed ID: 11169766
[TBL] [Abstract][Full Text] [Related]
6. Osteochondroma formation is independent of heparanase expression as revealed in a mouse model of hereditary multiple exostoses.
Mundy C; Chung J; Koyama E; Bunting S; Mahimkar R; Pacifici M
J Orthop Res; 2022 Oct; 40(10):2391-2401. PubMed ID: 34996123
[TBL] [Abstract][Full Text] [Related]
7. Palovarotene Inhibits Osteochondroma Formation in a Mouse Model of Multiple Hereditary Exostoses.
Inubushi T; Lemire I; Irie F; Yamaguchi Y
J Bone Miner Res; 2018 Apr; 33(4):658-666. PubMed ID: 29120519
[TBL] [Abstract][Full Text] [Related]
8. EXTra hit for mouse osteochondroma.
Bovée JV
Proc Natl Acad Sci U S A; 2010 Feb; 107(5):1813-4. PubMed ID: 20133829
[No Abstract] [Full Text] [Related]
9. Cell cycle deregulation and mosaic loss of Ext1 drive peripheral chondrosarcomagenesis in the mouse and reveal an intrinsic cilia deficiency.
de Andrea CE; Zhu JF; Jin H; Bovée JV; Jones KB
J Pathol; 2015 Jun; 236(2):210-8. PubMed ID: 25644707
[TBL] [Abstract][Full Text] [Related]
10. Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT.
de Andrea CE; Reijnders CM; Kroon HM; de Jong D; Hogendoorn PC; Szuhai K; Bovée JV
Oncogene; 2012 Mar; 31(9):1095-104. PubMed ID: 21804604
[TBL] [Abstract][Full Text] [Related]
11. EXT-mutation analysis and loss of heterozygosity in sporadic and hereditary osteochondromas and secondary chondrosarcomas.
Bovée JV; Cleton-Jansen AM; Wuyts W; Caethoven G; Taminiau AH; Bakker E; Van Hul W; Cornelisse CJ; Hogendoorn PC
Am J Hum Genet; 1999 Sep; 65(3):689-98. PubMed ID: 10441575
[TBL] [Abstract][Full Text] [Related]
12. Somatic loss of an EXT2 gene mutation during malignant progression in a patient with hereditary multiple osteochondromas.
Musso N; Caronia FP; Castorina S; Lo Monte AI; Barresi V; Condorelli DF
Cancer Genet; 2015 Mar; 208(3):62-7. PubMed ID: 25744876
[TBL] [Abstract][Full Text] [Related]
13. Ext-mutation analysis in Italian sporadic and hereditary osteochondromas.
Gigante M; Matera MG; Seripa D; Izzo AM; Venanzi R; Giannotti A; Digilio MC; Gravina C; Lazzari M; Monteleone G; Monteleone M; Dallapiccola B; Fazio VM
Int J Cancer; 2001 Nov; 95(6):378-83. PubMed ID: 11668521
[TBL] [Abstract][Full Text] [Related]
14. Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
Sinha S; Mundy C; Bechtold T; Sgariglia F; Ibrahim MM; Billings PC; Carroll K; Koyama E; Jones KB; Pacifici M
PLoS Genet; 2017 Apr; 13(4):e1006742. PubMed ID: 28445472
[TBL] [Abstract][Full Text] [Related]
15. A broad spectrum of genomic changes in latinamerican patients with EXT1/EXT2-CDG.
Delgado MA; Martinez-Domenech G; Sarrión P; Urreizti R; Zecchini L; Robledo HH; Segura F; de Kremer RD; Balcells S; Grinberg D; Asteggiano CG
Sci Rep; 2014 Sep; 4():6407. PubMed ID: 25230886
[TBL] [Abstract][Full Text] [Related]
16. Mutations in the EXT1 and EXT2 genes in Spanish patients with multiple osteochondromas.
Sarrión P; Sangorrin A; Urreizti R; Delgado A; Artuch R; Martorell L; Armstrong J; Anton J; Torner F; Vilaseca MA; Nevado J; Lapunzina P; Asteggiano CG; Balcells S; Grinberg D
Sci Rep; 2013; 3():1346. PubMed ID: 23439489
[TBL] [Abstract][Full Text] [Related]
17. Heparan sulfate deficiency leads to hypertrophic chondrocytes by increasing bone morphogenetic protein signaling.
Kawashima K; Ogawa H; Komura S; Ishihara T; Yamaguchi Y; Akiyama H; Matsumoto K
Osteoarthritis Cartilage; 2020 Nov; 28(11):1459-1470. PubMed ID: 32818603
[TBL] [Abstract][Full Text] [Related]
18. Breakpoint characterization of large deletions in EXT1 or EXT2 in 10 multiple osteochondromas families.
Jennes I; de Jong D; Mees K; Hogendoorn PC; Szuhai K; Wuyts W
BMC Med Genet; 2011 Jun; 12():85. PubMed ID: 21703028
[TBL] [Abstract][Full Text] [Related]
19. Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice.
Morimoto K; Shimizu T; Furukawa K; Morio H; Kurosawa H; Shirasawa T
Biochem Biophys Res Commun; 2002 Apr; 292(4):999-1009. PubMed ID: 11944914
[TBL] [Abstract][Full Text] [Related]
20. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]