548 related articles for article (PubMed ID: 20080645)
1. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
Gjerdrum C; Tiron C; Høiby T; Stefansson I; Haugen H; Sandal T; Collett K; Li S; McCormack E; Gjertsen BT; Micklem DR; Akslen LA; Glackin C; Lorens JB
Proc Natl Acad Sci U S A; 2010 Jan; 107(3):1124-9. PubMed ID: 20080645
[TBL] [Abstract][Full Text] [Related]
2. Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.
Kirane A; Ludwig KF; Sorrelle N; Haaland G; Sandal T; Ranaweera R; Toombs JE; Wang M; Dineen SP; Micklem D; Dellinger MT; Lorens JB; Brekken RA
Cancer Res; 2015 Sep; 75(18):3699-705. PubMed ID: 26206560
[TBL] [Abstract][Full Text] [Related]
3. The Receptor Tyrosine Kinase AXL Is Required at Multiple Steps of the Metastatic Cascade during HER2-Positive Breast Cancer Progression.
Goyette MA; Duhamel S; Aubert L; Pelletier A; Savage P; Thibault MP; Johnson RM; Carmeliet P; Basik M; Gaboury L; Muller WJ; Park M; Roux PP; Gratton JP; Côté JF
Cell Rep; 2018 May; 23(5):1476-1490. PubMed ID: 29719259
[TBL] [Abstract][Full Text] [Related]
4. R428, a selective small molecule inhibitor of Axl kinase, blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Holland SJ; Pan A; Franci C; Hu Y; Chang B; Li W; Duan M; Torneros A; Yu J; Heckrodt TJ; Zhang J; Ding P; Apatira A; Chua J; Brandt R; Pine P; Goff D; Singh R; Payan DG; Hitoshi Y
Cancer Res; 2010 Feb; 70(4):1544-54. PubMed ID: 20145120
[TBL] [Abstract][Full Text] [Related]
5. Axl activates autocrine transforming growth factor-β signaling in hepatocellular carcinoma.
Reichl P; Dengler M; van Zijl F; Huber H; Führlinger G; Reichel C; Sieghart W; Peck-Radosavljevic M; Grubinger M; Mikulits W
Hepatology; 2015 Mar; 61(3):930-41. PubMed ID: 25251599
[TBL] [Abstract][Full Text] [Related]
6. AXL is a key regulator of inherent and chemotherapy-induced invasion and predicts a poor clinical outcome in early-stage colon cancer.
Dunne PD; McArt DG; Blayney JK; Kalimutho M; Greer S; Wang T; Srivastava S; Ong CW; Arthur K; Loughrey M; Redmond K; Longley DB; Salto-Tellez M; Johnston PG; Van Schaeybroeck S
Clin Cancer Res; 2014 Jan; 20(1):164-75. PubMed ID: 24170546
[TBL] [Abstract][Full Text] [Related]
7. Vimentin regulates EMT induction by Slug and oncogenic H-Ras and migration by governing Axl expression in breast cancer.
Vuoriluoto K; Haugen H; Kiviluoto S; Mpindi JP; Nevo J; Gjerdrum C; Tiron C; Lorens JB; Ivaska J
Oncogene; 2011 Mar; 30(12):1436-48. PubMed ID: 21057535
[TBL] [Abstract][Full Text] [Related]
8. AXL induces epithelial-to-mesenchymal transition and regulates the function of breast cancer stem cells.
Asiedu MK; Beauchamp-Perez FD; Ingle JN; Behrens MD; Radisky DC; Knutson KL
Oncogene; 2014 Mar; 33(10):1316-24. PubMed ID: 23474758
[TBL] [Abstract][Full Text] [Related]
9. Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis.
Leconet W; Chentouf M; du Manoir S; Chevalier C; Sirvent A; Aït-Arsa I; Busson M; Jarlier M; Radosevic-Robin N; Theillet C; Chalbos D; Pasquet JM; Pèlegrin A; Larbouret C; Robert B
Clin Cancer Res; 2017 Jun; 23(11):2806-2816. PubMed ID: 27923843
[No Abstract] [Full Text] [Related]
10. The Axl receptor tyrosine kinase confers an adverse prognostic influence in pancreatic cancer and represents a new therapeutic target.
Koorstra JB; Karikari CA; Feldmann G; Bisht S; Rojas PL; Offerhaus GJ; Alvarez H; Maitra A
Cancer Biol Ther; 2009 Apr; 8(7):618-26. PubMed ID: 19252414
[TBL] [Abstract][Full Text] [Related]
11. Gas6/Axl Axis Contributes to Chemoresistance and Metastasis in Breast Cancer through Akt/GSK-3β/β-catenin Signaling.
Wang C; Jin H; Wang N; Fan S; Wang Y; Zhang Y; Wei L; Tao X; Gu D; Zhao F; Fang J; Yao M; Qin W
Theranostics; 2016; 6(8):1205-19. PubMed ID: 27279912
[TBL] [Abstract][Full Text] [Related]
12. Hypoxia stabilizes GAS6/Axl signaling in metastatic prostate cancer.
Mishra A; Wang J; Shiozawa Y; McGee S; Kim J; Jung Y; Joseph J; Berry JE; Havens A; Pienta KJ; Taichman RS
Mol Cancer Res; 2012 Jun; 10(6):703-12. PubMed ID: 22516347
[TBL] [Abstract][Full Text] [Related]
13. Multiple roles for the receptor tyrosine kinase axl in tumor formation.
Holland SJ; Powell MJ; Franci C; Chan EW; Friera AM; Atchison RE; McLaughlin J; Swift SE; Pali ES; Yam G; Wong S; Lasaga J; Shen MR; Yu S; Xu W; Hitoshi Y; Bogenberger J; Nör JE; Payan DG; Lorens JB
Cancer Res; 2005 Oct; 65(20):9294-303. PubMed ID: 16230391
[TBL] [Abstract][Full Text] [Related]
14. ΔNp63α Promotes Breast Cancer Cell Motility through the Selective Activation of Components of the Epithelial-to-Mesenchymal Transition Program.
Dang TT; Esparza MA; Maine EA; Westcott JM; Pearson GW
Cancer Res; 2015 Sep; 75(18):3925-35. PubMed ID: 26292362
[TBL] [Abstract][Full Text] [Related]
15. Biodegradable interstitial release polymer loading a novel small molecule targeting Axl receptor tyrosine kinase and reducing brain tumour migration and invasion.
Yen SY; Chen SR; Hsieh J; Li YS; Chuang SE; Chuang HM; Huang MH; Lin SZ; Harn HJ; Chiou TW
Oncogene; 2016 Apr; 35(17):2156-65. PubMed ID: 26257061
[TBL] [Abstract][Full Text] [Related]
16. MicroRNA 34a-AXL Axis Regulates Vasculogenic Mimicry Formation in Breast Cancer Cells.
Lim D; Cho JG; Yun E; Lee A; Ryu HY; Lee YJ; Yoon S; Chang W; Lee MS; Kwon BS; Kim J
Genes (Basel); 2020 Dec; 12(1):. PubMed ID: 33374832
[TBL] [Abstract][Full Text] [Related]
17. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance.
Byers LA; Diao L; Wang J; Saintigny P; Girard L; Peyton M; Shen L; Fan Y; Giri U; Tumula PK; Nilsson MB; Gudikote J; Tran H; Cardnell RJ; Bearss DJ; Warner SL; Foulks JM; Kanner SB; Gandhi V; Krett N; Rosen ST; Kim ES; Herbst RS; Blumenschein GR; Lee JJ; Lippman SM; Ang KK; Mills GB; Hong WK; Weinstein JN; Wistuba II; Coombes KR; Minna JD; Heymach JV
Clin Cancer Res; 2013 Jan; 19(1):279-90. PubMed ID: 23091115
[TBL] [Abstract][Full Text] [Related]
18. Axl mediates tumor invasion and chemosensitivity through PI3K/Akt signaling pathway and is transcriptionally regulated by slug in breast carcinoma.
Li Y; Jia L; Ren D; Liu C; Gong Y; Wang N; Zhang X; Zhao Y
IUBMB Life; 2014 Jul; 66(7):507-18. PubMed ID: 24984960
[TBL] [Abstract][Full Text] [Related]
19. Axl as a downstream effector of TGF-β1 via PI3K/Akt-PAK1 signaling pathway promotes tumor invasion and chemoresistance in breast carcinoma.
Li Y; Jia L; Liu C; Gong Y; Ren D; Wang N; Zhang X; Zhao Y
Tumour Biol; 2015 Feb; 36(2):1115-27. PubMed ID: 25327287
[TBL] [Abstract][Full Text] [Related]
20. Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways.
Wu X; Zahari MS; Ma B; Liu R; Renuse S; Sahasrabuddhe NA; Chen L; Chaerkady R; Kim MS; Zhong J; Jelinek C; Barbhuiya MA; Leal-Rojas P; Yang Y; Kashyap MK; Marimuthu A; Ling M; Fackler MJ; Merino V; Zhang Z; Zahnow CA; Gabrielson E; Stearns V; Roa JC; Sukumar S; Gill PS; Pandey A
Oncotarget; 2015 Oct; 6(30):29143-60. PubMed ID: 26356563
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
