278 related articles for article (PubMed ID: 20086033)
1. Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.
Lagas JS; Sparidans RW; Wagenaar E; Beijnen JH; Schinkel AH
Mol Pharmacol; 2010 Apr; 77(4):687-94. PubMed ID: 20086033
[TBL] [Abstract][Full Text] [Related]
2. Transport of diclofenac by breast cancer resistance protein (ABCG2) and stimulation of multidrug resistance protein 2 (ABCC2)-mediated drug transport by diclofenac and benzbromarone.
Lagas JS; van der Kruijssen CM; van de Wetering K; Beijnen JH; Schinkel AH
Drug Metab Dispos; 2009 Jan; 37(1):129-36. PubMed ID: 18845662
[TBL] [Abstract][Full Text] [Related]
3. Efflux transport of nicotine, cotinine and trans-3'-hydroxycotinine glucuronides by human hepatic transporters.
Järvinen E; Sjöstedt N; Koenderink JB; Kidron H; Finel M
Basic Clin Pharmacol Toxicol; 2019 Dec; 125(6):490-498. PubMed ID: 31237077
[TBL] [Abstract][Full Text] [Related]
4. The important role of Bcrp (Abcg2) in the biliary excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in mice.
Zamek-Gliszczynski MJ; Nezasa K; Tian X; Kalvass JC; Patel NJ; Raub TJ; Brouwer KL
Mol Pharmacol; 2006 Dec; 70(6):2127-33. PubMed ID: 16959944
[TBL] [Abstract][Full Text] [Related]
5. Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro.
Zhang Y; Han YH; Putluru SP; Matta MK; Kole P; Mandlekar S; Furlong MT; Liu T; Iyer RA; Marathe P; Yang Z; Lai Y; Rodrigues AD
Drug Metab Dispos; 2016 Mar; 44(3):320-8. PubMed ID: 26714763
[TBL] [Abstract][Full Text] [Related]
6. Bcrp1;Mdr1a/b;Mrp2 combination knockout mice: altered disposition of the dietary carcinogen PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) and its genotoxic metabolites.
Vlaming ML; Teunissen SF; van de Steeg E; van Esch A; Wagenaar E; Brunsveld L; de Greef TF; Rosing H; Schellens JH; Beijnen JH; Schinkel AH
Mol Pharmacol; 2014 Mar; 85(3):520-30. PubMed ID: 24334255
[TBL] [Abstract][Full Text] [Related]
7. Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice.
Zamek-Gliszczynski MJ; Nezasa K; Tian X; Bridges AS; Lee K; Belinsky MG; Kruh GD; Brouwer KL
J Pharmacol Exp Ther; 2006 Dec; 319(3):1485-91. PubMed ID: 16988054
[TBL] [Abstract][Full Text] [Related]
8. Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
Järvinen E; Troberg J; Kidron H; Finel M
Mol Pharm; 2017 Oct; 14(10):3299-3311. PubMed ID: 28850245
[TBL] [Abstract][Full Text] [Related]
9. Identification of the hepatic efflux transporters of organic anions using double-transfected Madin-Darby canine kidney II cells expressing human organic anion-transporting polypeptide 1B1 (OATP1B1)/multidrug resistance-associated protein 2, OATP1B1/multidrug resistance 1, and OATP1B1/breast cancer resistance protein.
Matsushima S; Maeda K; Kondo C; Hirano M; Sasaki M; Suzuki H; Sugiyama Y
J Pharmacol Exp Ther; 2005 Sep; 314(3):1059-67. PubMed ID: 15901800
[TBL] [Abstract][Full Text] [Related]
10. Human efflux transport of testosterone, epitestosterone and other androgen glucuronides.
Järvinen E; Kidron H; Finel M
J Steroid Biochem Mol Biol; 2020 Mar; 197():105518. PubMed ID: 31704245
[TBL] [Abstract][Full Text] [Related]
11. Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac.
Scialis RJ; Csanaky IL; Goedken MJ; Manautou JE
Drug Metab Dispos; 2015 Jul; 43(7):944-50. PubMed ID: 25897176
[TBL] [Abstract][Full Text] [Related]
12. Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen.
Adachi Y; Suzuki H; Schinkel AH; Sugiyama Y
Mol Pharmacol; 2005 Mar; 67(3):923-8. PubMed ID: 15598971
[TBL] [Abstract][Full Text] [Related]
13. Breast cancer resistance protein (Bcrp1/Abcg2) limits net intestinal uptake of quercetin in rats by facilitating apical efflux of glucuronides.
Sesink AL; Arts IC; de Boer VC; Breedveld P; Schellens JH; Hollman PC; Russel FG
Mol Pharmacol; 2005 Jun; 67(6):1999-2006. PubMed ID: 15749994
[TBL] [Abstract][Full Text] [Related]
14. Major glucuronide metabolites of testosterone are primarily transported by MRP2 and MRP3 in human liver, intestine and kidney.
Li CY; Basit A; Gupta A; Gáborik Z; Kis E; Prasad B
J Steroid Biochem Mol Biol; 2019 Jul; 191():105350. PubMed ID: 30959153
[TBL] [Abstract][Full Text] [Related]
15. Impact of abcc2 [multidrug resistance-associated protein (MRP) 2], abcc3 (MRP3), and abcg2 (breast cancer resistance protein) on the oral pharmacokinetics of methotrexate and its main metabolite 7-hydroxymethotrexate.
Vlaming ML; van Esch A; van de Steeg E; Pala Z; Wagenaar E; van Tellingen O; Schinkel AH
Drug Metab Dispos; 2011 Aug; 39(8):1338-44. PubMed ID: 21566011
[TBL] [Abstract][Full Text] [Related]
16. Evaluation of the role of breast cancer resistance protein (BCRP/ABCG2) and multidrug resistance-associated protein 4 (MRP4/ABCC4) in the urinary excretion of sulfate and glucuronide metabolites of edaravone (MCI-186; 3-methyl-1-phenyl-2-pyrazolin-5-one).
Mizuno N; Takahashi T; Kusuhara H; Schuetz JD; Niwa T; Sugiyama Y
Drug Metab Dispos; 2007 Nov; 35(11):2045-52. PubMed ID: 17682070
[TBL] [Abstract][Full Text] [Related]
17. Multiple mechanisms are involved in the biliary excretion of acetaminophen sulfate in the rat: role of Mrp2 and Bcrp1.
Zamek-Gliszczynski MJ; Hoffmaster KA; Tian X; Zhao R; Polli JW; Humphreys JE; Webster LO; Bridges AS; Kalvass JC; Brouwer KL
Drug Metab Dispos; 2005 Aug; 33(8):1158-65. PubMed ID: 15860656
[TBL] [Abstract][Full Text] [Related]
18. Altered hepatobiliary disposition of 5 (and 6)-carboxy-2',7'-dichlorofluorescein in Abcg2 (Bcrp1) and Abcc2 (Mrp2) knockout mice.
Nezasa K; Tian X; Zamek-Gliszczynski MJ; Patel NJ; Raub TJ; Brouwer KL
Drug Metab Dispos; 2006 Apr; 34(4):718-23. PubMed ID: 16434545
[TBL] [Abstract][Full Text] [Related]
19. Identification and Characterization of Efflux Transporters That Modulate the Subtoxic Disposition of Diclofenac and Its Metabolites.
Scialis RJ; Aleksunes LM; Csanaky IL; Klaassen CD; Manautou JE
Drug Metab Dispos; 2019 Oct; 47(10):1080-1092. PubMed ID: 31399506
[TBL] [Abstract][Full Text] [Related]
20. Breast Cancer Resistance Protein and Multidrug Resistance Protein 2 Regulate the Disposition of Acacetin Glucuronides.
Jiang H; Yu J; Zheng H; Chen J; Wu J; Qi X; Wang Y; Wang X; Hu M; Zhu L; Liu Z
Pharm Res; 2017 Jul; 34(7):1402-1415. PubMed ID: 28421306
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
