BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

152 related articles for article (PubMed ID: 20086146)

  • 1. Penicillin sulfone inhibitors of class D beta-lactamases.
    Drawz SM; Bethel CR; Doppalapudi VR; Sheri A; Pagadala SR; Hujer AM; Skalweit MJ; Anderson VE; Chen SG; Buynak JD; Bonomo RA
    Antimicrob Agents Chemother; 2010 Apr; 54(4):1414-24. PubMed ID: 20086146
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and crystal structures of 6-alkylidene-2'-substituted penicillanic acid sulfones as potent inhibitors of Acinetobacter baumannii OXA-24 carbapenemase.
    Bou G; Santillana E; Sheri A; Beceiro A; Sampson JM; Kalp M; Bethel CR; Distler AM; Drawz SM; Pagadala SR; van den Akker F; Bonomo RA; Romero A; Buynak JD
    J Am Chem Soc; 2010 Sep; 132(38):13320-31. PubMed ID: 20822105
    [TBL] [Abstract][Full Text] [Related]  

  • 3. An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains.
    Lupo V; Mercuri PS; Frère JM; Joris B; Galleni M; Baurain D; Kerff F
    Microbiol Spectr; 2022 Apr; 10(2):e0031522. PubMed ID: 35311582
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Penicillin-Binding Proteins, β-Lactamases, and β-Lactamase Inhibitors in β-Lactam-Producing Actinobacteria: Self-Resistance Mechanisms.
    Martin JF; Alvarez-Alvarez R; Liras P
    Int J Mol Sci; 2022 May; 23(10):. PubMed ID: 35628478
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Three decades of beta-lactamase inhibitors.
    Drawz SM; Bonomo RA
    Clin Microbiol Rev; 2010 Jan; 23(1):160-201. PubMed ID: 20065329
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exploiting the Carboxylate-Binding Pocket of β-Lactamase Enzymes Using a Focused DNA-Encoded Chemical Library.
    Park S; Fan J; Chamakuri S; Palaniappan M; Sharma K; Qin X; Wang J; Tan Z; Judge A; Hu L; Sankaran B; Li F; Prasad BVV; Matzuk MM; Palzkill T
    J Med Chem; 2024 Jan; 67(1):620-642. PubMed ID: 38117688
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Comparison of beta-lactamases of classes A and D: 1.5-A crystallographic structure of the class D OXA-1 oxacillinase.
    Sun T; Nukaga M; Mayama K; Braswell EH; Knox JR
    Protein Sci; 2003 Jan; 12(1):82-91. PubMed ID: 12493831
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of
    Taylor DM; Anglin J; Hu L; Wang L; Sankaran B; Wang J; Matzuk MM; Prasad BVV; Palzkill T
    ACS Infect Dis; 2021 Dec; 7(12):3345-3354. PubMed ID: 34817169
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Detecting a quasi-stable imine species on the reaction pathway of SHV-1 β-lactamase and 6β-(hydroxymethyl)penicillanic acid sulfone.
    Che T; Rodkey EA; Bethel CR; Shanmugam S; Ding Z; Pusztai-Carey M; Nottingham M; Chai W; Buynak JD; Bonomo RA; van den Akker F; Carey PR
    Biochemistry; 2015 Jan; 54(3):734-43. PubMed ID: 25536850
    [TBL] [Abstract][Full Text] [Related]  

  • 10. β-Lactamase inhibition by 7-alkylidenecephalosporin sulfones: allylic transposition and formation of an unprecedented stabilized acyl-enzyme.
    Rodkey EA; McLeod DC; Bethel CR; Smith KM; Xu Y; Chai W; Che T; Carey PR; Bonomo RA; van den Akker F; Buynak JD
    J Am Chem Soc; 2013 Dec; 135(49):18358-69. PubMed ID: 24219313
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Studies on enmetazobactam clarify mechanisms of widely used β-lactamase inhibitors.
    Lang PA; Raj R; Tumber A; Lohans CT; Rabe P; Robinson CV; Brem J; Schofield CJ
    Proc Natl Acad Sci U S A; 2022 May; 119(18):e2117310119. PubMed ID: 35486701
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of the extended substrate spectrum of the class A β-lactamase CESS-1 from Stenotrophomonas sp. and structure-based investigation into its substrate preference.
    Jeong BG; Kim MY; Jeong CS; Do H; Hwang J; Lee JH; Cha SS
    Int J Antimicrob Agents; 2024 Jun; 63(6):107171. PubMed ID: 38588869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fragment-based inhibitor discovery against β-lactamase.
    Nichols DA; Renslo AR; Chen Y
    Future Med Chem; 2014 Mar; 6(4):413-27. PubMed ID: 24635522
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries.
    Taylor DM; Anglin J; Park S; Ucisik MN; Faver JC; Simmons N; Jin Z; Palaniappan M; Nyshadham P; Li F; Campbell J; Hu L; Sankaran B; Prasad BVV; Huang H; Matzuk MM; Palzkill T
    ACS Infect Dis; 2020 May; 6(5):1214-1227. PubMed ID: 32182432
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of products of inhibition of GES-2 beta-lactamase by tazobactam by x-ray crystallography and spectrometry.
    Frase H; Smith CA; Toth M; Champion MM; Mobashery S; Vakulenko SB
    J Biol Chem; 2011 Apr; 286(16):14396-409. PubMed ID: 21345789
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases.
    Ganta SR; Perumal S; Pagadala SR; Samuelsen O; Spencer J; Pratt RF; Buynak JD
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1618-22. PubMed ID: 19243936
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436.
    Lund BA; Thomassen AM; Carlsen TJW; Leiros HKS
    Acta Crystallogr F Struct Biol Commun; 2021 Sep; 77(Pt 9):312-318. PubMed ID: 34473108
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Class C beta-lactamases operate at the diffusion limit for turnover of their preferred cephalosporin substrates.
    Bulychev A; Mobashery S
    Antimicrob Agents Chemother; 1999 Jul; 43(7):1743-6. PubMed ID: 10390233
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antibiotic use in Australian and Swedish primary care: a cross-country comparison.
    Andersson K; van Driel M; Hedin K; Hollingworth S; Merlo G
    Scand J Prim Health Care; 2022 Mar; 40(1):95-103. PubMed ID: 35166180
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Involvement of a Novel Class C Beta-Lactamase in the Transglutaminase Mediated Cross-Linking Cascade of Streptomyces mobaraensis DSM 40847.
    Zindel S; Ehret V; Ehret M; Hentschel M; Witt S; Krämer A; Fiebig D; Jüttner N; Fröls S; Pfeifer F; Fuchsbauer HL
    PLoS One; 2016; 11(2):e0149145. PubMed ID: 26886195
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.