BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 20089394)

  • 1. Structural studies of the spliceosome: blind men and an elephant.
    Newman AJ; Nagai K
    Curr Opin Struct Biol; 2010 Feb; 20(1):82-9. PubMed ID: 20089394
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure and assembly of the spliceosomal snRNPs. Novartis Medal Lecture.
    Nagai K; Muto Y; Pomeranz Krummel DA; Kambach C; Ignjatovic T; Walke S; Kuglstatter A
    Biochem Soc Trans; 2001 May; 29(Pt 2):15-26. PubMed ID: 11356120
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
    Bertram K; Agafonov DE; Dybkov O; Haselbach D; Leelaram MN; Will CL; Urlaub H; Kastner B; Lührmann R; Stark H
    Cell; 2017 Aug; 170(4):701-713.e11. PubMed ID: 28781166
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comprehensive in vivo RNA-binding site analyses reveal a role of Prp8 in spliceosomal assembly.
    Li X; Zhang W; Xu T; Ramsey J; Zhang L; Hill R; Hansen KC; Hesselberth JR; Zhao R
    Nucleic Acids Res; 2013 Apr; 41(6):3805-18. PubMed ID: 23393194
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The assembly of a spliceosomal small nuclear ribonucleoprotein particle.
    Patel SB; Bellini M
    Nucleic Acids Res; 2008 Nov; 36(20):6482-93. PubMed ID: 18854356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spliceosome structure and function.
    Will CL; Lührmann R
    Cold Spring Harb Perspect Biol; 2011 Jul; 3(7):. PubMed ID: 21441581
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The large N-terminal region of the Brr2 RNA helicase guides productive spliceosome activation.
    Absmeier E; Wollenhaupt J; Mozaffari-Jovin S; Becke C; Lee CT; Preussner M; Heyd F; Urlaub H; Lührmann R; Santos KF; Wahl MC
    Genes Dev; 2015 Dec; 29(24):2576-87. PubMed ID: 26637280
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.
    Nancollis V; Ruckshanthi JP; Frazer LN; O'Keefe RT
    J Cell Biochem; 2013 Dec; 114(12):2770-84. PubMed ID: 23857713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Suppressors of a cold-sensitive mutation in yeast U4 RNA define five domains in the splicing factor Prp8 that influence spliceosome activation.
    Kuhn AN; Brow DA
    Genetics; 2000 Aug; 155(4):1667-82. PubMed ID: 10924465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution.
    Pomeranz Krummel DA; Oubridge C; Leung AK; Li J; Nagai K
    Nature; 2009 Mar; 458(7237):475-80. PubMed ID: 19325628
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure and assembly of the spliceosomal small nuclear ribonucleoprotein particles.
    Kambach C; Walke S; Nagai K
    Curr Opin Struct Biol; 1999 Apr; 9(2):222-30. PubMed ID: 10322216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The U1 snRNP base pairs with the 5' splice site within a penta-snRNP complex.
    Malca H; Shomron N; Ast G
    Mol Cell Biol; 2003 May; 23(10):3442-55. PubMed ID: 12724403
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural studies of the spliceosome: zooming into the heart of the machine.
    Galej WP; Nguyen TH; Newman AJ; Nagai K
    Curr Opin Struct Biol; 2014 Apr; 25(100):57-66. PubMed ID: 24480332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A forward genetic screen in C. elegans identifies conserved residues of spliceosomal proteins PRP8 and SNRNP200/BRR2 with a role in maintaining 5' splice site identity.
    Cartwright-Acar CH; Osterhoudt K; Suzuki JMNGL; Gomez DR; Katzman S; Zahler AM
    Nucleic Acids Res; 2022 Nov; 50(20):11834-11857. PubMed ID: 36321655
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Crystal structure of a core spliceosomal protein interface.
    Schellenberg MJ; Edwards RA; Ritchie DB; Kent OA; Golas MM; Stark H; Lührmann R; Glover JN; MacMillan AM
    Proc Natl Acad Sci U S A; 2006 Jan; 103(5):1266-71. PubMed ID: 16432215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A noncanonical PWI domain in the N-terminal helicase-associated region of the spliceosomal Brr2 protein.
    Absmeier E; Rosenberger L; Apelt L; Becke C; Santos KF; Stelzl U; Wahl MC
    Acta Crystallogr D Biol Crystallogr; 2015 Apr; 71(Pt 4):762-71. PubMed ID: 25849387
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pre-mRNA splicing: the discovery of a new spliceosome doubles the challenge.
    Tarn WY; Steitz JA
    Trends Biochem Sci; 1997 Apr; 22(4):132-7. PubMed ID: 9149533
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural dynamics of the N-terminal domain and the Switch loop of Prp8 during spliceosome assembly and activation.
    Jia X; Sun C
    Nucleic Acids Res; 2018 May; 46(8):3833-3840. PubMed ID: 29635373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural studies of the endogenous spliceosome - The supraspliceosome.
    Sperling J; Sperling R
    Methods; 2017 Aug; 125():70-83. PubMed ID: 28412289
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
    Bertram K; Agafonov DE; Liu WT; Dybkov O; Will CL; Hartmuth K; Urlaub H; Kastner B; Stark H; Lührmann R
    Nature; 2017 Feb; 542(7641):318-323. PubMed ID: 28076346
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.