BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

381 related articles for article (PubMed ID: 20093281)

  • 1. Metformin suppresses hepatic gluconeogenesis through induction of SIRT1 and GCN5.
    Caton PW; Nayuni NK; Kieswich J; Khan NQ; Yaqoob MM; Corder R
    J Endocrinol; 2010 Apr; 205(1):97-106. PubMed ID: 20093281
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metformin opposes impaired AMPK and SIRT1 function and deleterious changes in core clock protein expression in white adipose tissue of genetically-obese db/db mice.
    Caton PW; Kieswich J; Yaqoob MM; Holness MJ; Sugden MC
    Diabetes Obes Metab; 2011 Dec; 13(12):1097-104. PubMed ID: 21733059
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange.
    Liu Y; Dentin R; Chen D; Hedrick S; Ravnskjaer K; Schenk S; Milne J; Meyers DJ; Cole P; Yates J; Olefsky J; Guarente L; Montminy M
    Nature; 2008 Nov; 456(7219):269-73. PubMed ID: 18849969
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metformin inhibits hepatic gluconeogenesis through AMP-activated protein kinase-dependent regulation of the orphan nuclear receptor SHP.
    Kim YD; Park KG; Lee YS; Park YY; Kim DK; Nedumaran B; Jang WG; Cho WJ; Ha J; Lee IK; Lee CH; Choi HS
    Diabetes; 2008 Feb; 57(2):306-14. PubMed ID: 17909097
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.
    Dominy JE; Lee Y; Jedrychowski MP; Chim H; Jurczak MJ; Camporez JP; Ruan HB; Feldman J; Pierce K; Mostoslavsky R; Denu JM; Clish CB; Yang X; Shulman GI; Gygi SP; Puigserver P
    Mol Cell; 2012 Dec; 48(6):900-13. PubMed ID: 23142079
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PPP1R3C mediates metformin-inhibited hepatic gluconeogenesis.
    Ji X; Wang S; Tang H; Zhang Y; Zhou F; Zhang L; Zhu Q; Zhu K; Liu Q; Liu Y; Wang X; Zhou L
    Metabolism; 2019 Sep; 98():62-75. PubMed ID: 31181215
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Berberine inhibits hepatic gluconeogenesis via the LKB1-AMPK-TORC2 signaling pathway in streptozotocin-induced diabetic rats.
    Jiang SJ; Dong H; Li JB; Xu LJ; Zou X; Wang KF; Lu FE; Yi P
    World J Gastroenterol; 2015 Jul; 21(25):7777-85. PubMed ID: 26167077
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans.
    Banerjee J; Bruckbauer A; Zemel MB
    Metabolism; 2016 Nov; 65(11):1679-1691. PubMed ID: 27456392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fructose induces gluconeogenesis and lipogenesis through a SIRT1-dependent mechanism.
    Caton PW; Nayuni NK; Khan NQ; Wood EG; Corder R
    J Endocrinol; 2011 Mar; 208(3):273-83. PubMed ID: 21212096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amelioration of glucose tolerance by hepatic inhibition of nuclear factor kappaB in db/db mice.
    Tamura Y; Ogihara T; Uchida T; Ikeda F; Kumashiro N; Nomiyama T; Sato F; Hirose T; Tanaka Y; Mochizuki H; Kawamori R; Watada H
    Diabetologia; 2007 Jan; 50(1):131-41. PubMed ID: 17093946
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AMPK-dependent repression of hepatic gluconeogenesis via disruption of CREB.CRTC2 complex by orphan nuclear receptor small heterodimer partner.
    Lee JM; Seo WY; Song KH; Chanda D; Kim YD; Kim DK; Lee MW; Ryu D; Kim YH; Noh JR; Lee CH; Chiang JY; Koo SH; Choi HS
    J Biol Chem; 2010 Oct; 285(42):32182-91. PubMed ID: 20688914
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator.
    Tavares CD; Sharabi K; Dominy JE; Lee Y; Isasa M; Orozco JM; Jedrychowski MP; Kamenecka TM; Griffin PR; Gygi SP; Puigserver P
    J Biol Chem; 2016 May; 291(20):10635-45. PubMed ID: 27022023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state.
    Foretz M; Hébrard S; Leclerc J; Zarrinpashneh E; Soty M; Mithieux G; Sakamoto K; Andreelli F; Viollet B
    J Clin Invest; 2010 Jul; 120(7):2355-69. PubMed ID: 20577053
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transcription factors and coactivators controlling nutrient and hormonal regulation of hepatic gluconeogenesis.
    Jitrapakdee S
    Int J Biochem Cell Biol; 2012 Jan; 44(1):33-45. PubMed ID: 22004992
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metformin primarily decreases plasma glucose not by gluconeogenesis suppression but by activating glucose utilization in a non-obese type 2 diabetes Goto-Kakizaki rats.
    Yoshida T; Okuno A; Tanaka J; Takahashi K; Nakashima R; Kanda S; Ogawa J; Hagisawa Y; Fujiwara T
    Eur J Pharmacol; 2009 Nov; 623(1-3):141-7. PubMed ID: 19765581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CITED2 links hormonal signaling to PGC-1α acetylation in the regulation of gluconeogenesis.
    Sakai M; Matsumoto M; Tujimura T; Yongheng C; Noguchi T; Inagaki K; Inoue H; Hosooka T; Takazawa K; Kido Y; Yasuda K; Hiramatsu R; Matsuki Y; Kasuga M
    Nat Med; 2012 Mar; 18(4):612-7. PubMed ID: 22426420
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Epigenetic modulation of PGC-1α activity by GCN5 inhibitors: WO2010007085.
    Carradori S; Secci D; Mai A
    Expert Opin Ther Pat; 2011 Oct; 21(10):1651-6. PubMed ID: 21756203
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CREB regulates hepatic gluconeogenesis through the coactivator PGC-1.
    Herzig S; Long F; Jhala US; Hedrick S; Quinn R; Bauer A; Rudolph D; Schutz G; Yoon C; Puigserver P; Spiegelman B; Montminy M
    Nature; 2001 Sep; 413(6852):179-83. PubMed ID: 11557984
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sodium meta-arsenite ameliorates hyperglycemia in obese diabetic db/db mice by inhibition of hepatic gluconeogenesis.
    Lee YS; Lee EK; Oh HH; Choi CS; Kim S; Jun HS
    J Diabetes Res; 2014; 2014():961732. PubMed ID: 25610880
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Extracellular visfatin activates gluconeogenesis in HepG2 cells through the classical PKA/CREB-dependent pathway.
    Choi YJ; Choi SE; Ha ES; Kang Y; Han SJ; Kim DJ; Lee KW; Kim HJ
    Horm Metab Res; 2014 Apr; 46(4):233-9. PubMed ID: 24627100
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.