BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 20095973)

  • 1. Polyamines as mediators of APC-dependent intestinal carcinogenesis and cancer chemoprevention.
    Rial NS; Meyskens FL; Gerner EW
    Essays Biochem; 2009 Nov; 46():111-24. PubMed ID: 20095973
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis.
    Ignatenko NA; Besselsen DG; Stringer DE; Blohm-Mangone KA; Cui H; Gerner EW
    Nutr Cancer; 2008; 60 Suppl 1():30-5. PubMed ID: 19003578
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Efficacy and safety of eflornithine (CPP-1X)/sulindac combination therapy versus each as monotherapy in patients with familial adenomatous polyposis (FAP): design and rationale of a randomized, double-blind, Phase III trial.
    Burke CA; Dekker E; Samadder NJ; Stoffel E; Cohen A
    BMC Gastroenterol; 2016 Aug; 16(1):87. PubMed ID: 27480131
    [TBL] [Abstract][Full Text] [Related]  

  • 4. APC-dependent changes in expression of genes influencing polyamine metabolism, and consequences for gastrointestinal carcinogenesis, in the Min mouse.
    Erdman SH; Ignatenko NA; Powell MB; Blohm-Mangone KA; Holubec H; Guillén-Rodriguez JM; Gerner EW
    Carcinogenesis; 1999 Sep; 20(9):1709-13. PubMed ID: 10469614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Impact of dietary amino acids and polyamines on intestinal carcinogenesis and chemoprevention in mouse models.
    Gerner EW
    Biochem Soc Trans; 2007 Apr; 35(Pt 2):322-5. PubMed ID: 17371270
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Rationale for, and design of, a clinical trial targeting polyamine metabolism for colon cancer chemoprevention.
    Gerner EW; Meyskens FL; Goldschmid S; Lance P; Pelot D
    Amino Acids; 2007 Aug; 33(2):189-95. PubMed ID: 17396214
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Role of dietary polyamines in a phase III clinical trial of difluoromethylornithine (DFMO) and sulindac for prevention of sporadic colorectal adenomas.
    Raj KP; Zell JA; Rock CL; McLaren CE; Zoumas-Morse C; Gerner EW; Meyskens FL
    Br J Cancer; 2013 Feb; 108(3):512-8. PubMed ID: 23340449
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of obesity in a randomized placebo-controlled trial of difluoromethylornithine (DFMO) + sulindac for the prevention of sporadic colorectal adenomas.
    Zell JA; Lin BS; Madson N; McLaren CE; Gerner EW; Meyskens FL
    Cancer Causes Control; 2012 Oct; 23(10):1739-44. PubMed ID: 22907422
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cancer pharmacoprevention: Targeting polyamine metabolism to manage risk factors for colon cancer.
    Gerner EW; Bruckheimer E; Cohen A
    J Biol Chem; 2018 Nov; 293(48):18770-18778. PubMed ID: 30355737
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene.
    Martinez ME; O'Brien TG; Fultz KE; Babbar N; Yerushalmi H; Qu N; Guo Y; Boorman D; Einspahr J; Alberts DS; Gerner EW
    Proc Natl Acad Sci U S A; 2003 Jun; 100(13):7859-64. PubMed ID: 12810952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Levels of rectal mucosal polyamines and prostaglandin E2 predict ability of DFMO and sulindac to prevent colorectal adenoma.
    Thompson PA; Wertheim BC; Zell JA; Chen WP; McLaren CE; LaFleur BJ; Meyskens FL; Gerner EW
    Gastroenterology; 2010 Sep; 139(3):797-805, 805.e1. PubMed ID: 20538001
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A randomized, placebo-controlled trial of low-dose alpha-difluoromethylornithine in individuals at risk for colorectal cancer.
    Love RR; Jacoby R; Newton MA; Tutsch KD; Simon K; Pomplun M; Verma AK
    Cancer Epidemiol Biomarkers Prev; 1998 Nov; 7(11):989-92. PubMed ID: 9829706
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prostanoids, ornithine decarboxylase, and polyamines in primary chemoprevention of familial adenomatous polyposis.
    Giardiello FM; Casero RA; Hamilton SR; Hylind LM; Trimbath JD; Geiman DE; Judge KR; Hubbard W; Offerhaus GJ; Yang VW
    Gastroenterology; 2004 Feb; 126(2):425-31. PubMed ID: 14762779
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phospho-sulindac (OXT-328) combined with difluoromethylornithine prevents colon cancer in mice.
    Mackenzie GG; Ouyang N; Xie G; Vrankova K; Huang L; Sun Y; Komninou D; Kopelovich L; Rigas B
    Cancer Prev Res (Phila); 2011 Jul; 4(7):1052-60. PubMed ID: 21464038
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DFMO: targeted risk reduction therapy for colorectal neoplasia.
    Laukaitis CM; Gerner EW
    Best Pract Res Clin Gastroenterol; 2011 Aug; 25(4-5):495-506. PubMed ID: 22122766
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination chemoprevention for colon cancer targeting polyamine synthesis and inflammation.
    Gerner EW; Meyskens FL
    Clin Cancer Res; 2009 Feb; 15(3):758-61. PubMed ID: 19188144
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Difluoromethylornithine plus sulindac for the prevention of sporadic colorectal adenomas: a randomized placebo-controlled, double-blind trial.
    Meyskens FL; McLaren CE; Pelot D; Fujikawa-Brooks S; Carpenter PM; Hawk E; Kelloff G; Lawson MJ; Kidao J; McCracken J; Albers CG; Ahnen DJ; Turgeon DK; Goldschmid S; Lance P; Hagedorn CH; Gillen DL; Gerner EW
    Cancer Prev Res (Phila); 2008 Jun; 1(1):32-8. PubMed ID: 18841250
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of difluoromethylornithine (DFMO) as a chemoprevention agent.
    Meyskens FL; Gerner EW
    Clin Cancer Res; 1999 May; 5(5):945-51. PubMed ID: 10353725
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Revival of 2-(difluoromethyl)ornithine (DFMO), an inhibitor of polyamine biosynthesis, as a cancer chemopreventive agent.
    Raul F
    Biochem Soc Trans; 2007 Apr; 35(Pt 2):353-5. PubMed ID: 17371277
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ornithine decarboxylase-1 polymorphism, chemoprevention with eflornithine and sulindac, and outcomes among colorectal adenoma patients.
    Zell JA; McLaren CE; Chen WP; Thompson PA; Gerner EW; Meyskens FL
    J Natl Cancer Inst; 2010 Oct; 102(19):1513-6. PubMed ID: 20798393
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.