BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 20097072)

  • 1. Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
    Chowdhury MA; Abdellatif KR; Dong Y; Yu G; Huang Z; Rahman M; Das D; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2010 Feb; 20(4):1324-9. PubMed ID: 20097072
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Velázquez C; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem; 2008 Nov; 16(22):9694-8. PubMed ID: 18930406
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Das D; Yu G; Velázquez C; Suresh MR; Knaus EE
    Bioorg Med Chem; 2009 Jul; 17(14):5182-8. PubMed ID: 19500994
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: synthesis, nitric oxide release studies and anti-inflammatory activities.
    Abdellatif KR; Chowdhury MA; Dong Y; Knaus EE
    Bioorg Med Chem; 2008 Jul; 16(13):6528-34. PubMed ID: 18513975
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Velázquez CA; Huang Z; Dong Y; Das D; Yu G; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2010 Aug; 20(15):4544-9. PubMed ID: 20576432
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Novel nonsteroidal antiinflammatory drugs possessing a nitric oxide donor diazen-1-ium-1,2-diolate moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez C; Praveen Rao PN; Knaus EE
    J Med Chem; 2005 Jun; 48(12):4061-7. PubMed ID: 15943479
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Dinitroglyceryl and diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of aspirin, indomethacin and ibuprofen: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Das D; Yu G; Velázquez CA; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2009 Jun; 19(11):3014-8. PubMed ID: 19419861
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: synthesis, cyclooxygenase inhibition, and nitric oxide release studies.
    Abdellatif KR; Chowdhury MA; Dong Y; Chen QH; Knaus EE
    Bioorg Med Chem; 2008 Mar; 16(6):3302-8. PubMed ID: 18096394
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: synthesis, biological evaluation and nitric oxide release studies.
    Abdellatif KR; Huang Z; Chowdhury MA; Kaufman S; Knaus EE
    Bioorg Med Chem Lett; 2011 Jul; 21(13):3951-6. PubMed ID: 21641217
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents.
    Velázquez C; Rao PN; McDonald R; Knaus EE
    Bioorg Med Chem; 2005 Apr; 13(8):2749-57. PubMed ID: 15781386
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of new 4-[2-(4-methyl(amino)sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1,2,3,6-tetrahydropyridines: a search for novel nitric oxide donor anti-inflammatory agents.
    Chowdhury MA; Abdellatif KR; Dong Y; Knaus EE
    Bioorg Med Chem; 2008 Oct; 16(19):8882-8. PubMed ID: 18789699
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity.
    Chowdhury MA; Abdellatif KR; Dong Y; Das D; Suresh MR; Knaus EE
    Bioorg Med Chem Lett; 2008 Dec; 18(23):6138-41. PubMed ID: 18945614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies.
    Abdellatif KR; Dong Y; Chen QH; Chowdhury MA; Knaus EE
    Bioorg Med Chem; 2007 Nov; 15(21):6796-801. PubMed ID: 17764958
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aspirin analogues as dual cyclooxygenase-2/5-lipoxygenase inhibitors: synthesis, nitric oxide release, molecular modeling, and biological evaluation as anti-inflammatory agents.
    Kaur J; Bhardwaj A; Huang Z; Knaus EE
    ChemMedChem; 2012 Jan; 7(1):144-50. PubMed ID: 22095955
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Second-generation aspirin and indomethacin prodrugs possessing an O(2)-(acetoxymethyl)-1-(2-carboxypyrrolidin-1-yl)diazenium-1,2-diolate nitric oxide donor moiety: design, synthesis, biological evaluation, and nitric oxide release studies.
    Velázquez CA; Chen QH; Citro ML; Keefer LK; Knaus EE
    J Med Chem; 2008 Mar; 51(6):1954-61. PubMed ID: 18314945
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NO-donors (VII [1]): synthesis and cyclooxygenase inhibitory properties of N-and S-nitrooxypivaloyl-cysteine derivatives of naproxen -- a novel type of NO-NSAID.
    Kartasasmita RE; Laufer S; Lehmann J
    Arch Pharm (Weinheim); 2002 Aug; 335(8):363-6. PubMed ID: 12397619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design, synthesis, and biological evaluation of N-acetyl-2-(or 3-)carboxymethylbenzenesulfonamides as cyclooxygenase isozyme inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Aug; 13(15):4694-703. PubMed ID: 15914011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles.
    Ranatunge RR; Augustyniak M; Bandarage UK; Earl RA; Ellis JL; Garvey DS; Janero DR; Letts LG; Martino AM; Murty MG; Richardson SK; Schroeder JD; Shumway MJ; Tam SW; Trocha AM; Young DV
    J Med Chem; 2004 Apr; 47(9):2180-93. PubMed ID: 15084117
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: nitric oxide-donor naproxen prodrugs.
    Ranatunge RR; Augustyniak ME; Dhawan V; Ellis JL; Garvey DS; Janero DR; Letts LG; Richardson SK; Shumway MJ; Trocha AM; Young DV; Zemtseva IS
    Bioorg Med Chem; 2006 Apr; 14(8):2589-99. PubMed ID: 16356728
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors.
    Chen QH; Rao PN; Knaus EE
    Bioorg Med Chem; 2005 Apr; 13(7):2459-68. PubMed ID: 15755648
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.