These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 20100008)

  • 1. Spiroindenes and spiroindanes as antagonists of CC chemokine receptor 2: WO 2009023754.
    Carter PH
    Expert Opin Ther Pat; 2010 Feb; 20(2):283-9. PubMed ID: 20100008
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Recent developments in CCR2 antagonists.
    Xia M; Sui Z
    Expert Opin Ther Pat; 2009 Mar; 19(3):295-303. PubMed ID: 19441905
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel, orally bioavailable gamma-aminoamide CC chemokine receptor 2 (CCR2) antagonists.
    Pasternak A; Marino D; Vicario PP; Ayala JM; Cascierri MA; Parsons W; Mills SG; Maccoss M; Yang L
    J Med Chem; 2006 Aug; 49(16):4801-4. PubMed ID: 16884289
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-kinetic relationships--an overlooked parameter in hit-to-lead optimization: a case of cyclopentylamines as chemokine receptor 2 antagonists.
    Vilums M; Zweemer AJ; Yu Z; de Vries H; Hillger JM; Wapenaar H; Bollen IA; Barmare F; Gross R; Clemens J; Krenitsky P; Brussee J; Stamos D; Saunders J; Heitman LH; Ijzerman AP
    J Med Chem; 2013 Oct; 56(19):7706-14. PubMed ID: 24028535
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Progress in the discovery of CC chemokine receptor 2 antagonists, 2009 - 2012.
    Carter PH
    Expert Opin Ther Pat; 2013 May; 23(5):549-68. PubMed ID: 23428142
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of spirocyclic antagonists of CCR2 (chemokine CC receptor subtype 2).
    Strunz AK; Zweemer AJ; Weiss C; Schepmann D; Junker A; Heitman LH; Koch M; Wünsch B
    Bioorg Med Chem; 2015 Jul; 23(14):4034-49. PubMed ID: 25766632
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemokine receptor antagonists: Part 1.
    Pease JE; Horuk R
    Expert Opin Ther Pat; 2009 Jan; 19(1):39-58. PubMed ID: 19441897
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of trisubstituted cyclohexanes as potent CC chemokine receptor 2 (CCR2) antagonists.
    Cherney RJ; Brogan JB; Mo R; Lo YC; Yang G; Miller PB; Scherle PA; Molino BF; Carter PH; Decicco CP
    Bioorg Med Chem Lett; 2009 Feb; 19(3):597-601. PubMed ID: 19131247
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Conformational studies of 3-amino-1-alkyl-cyclopentane carboxamide CCR2 antagonists leading to new spirocyclic antagonists.
    Pasternak A; Goble SD; Doss GA; Tsou NN; Butora G; Vicario PP; Ayala JM; Struthers M; Demartino JA; Mills SG; Yang L
    Bioorg Med Chem Lett; 2008 Feb; 18(4):1374-7. PubMed ID: 18215519
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and evaluation of cis-3,4-disubstituted piperidines as potent CC chemokine receptor 2 (CCR2) antagonists.
    Cherney RJ; Nelson DJ; Lo YC; Yang G; Scherle PA; Jezak H; Solomon KA; Carter PH; Decicco CP
    Bioorg Med Chem Lett; 2008 Sep; 18(18):5063-5. PubMed ID: 18722120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of 3-piperidinyl-1-cyclopentanecarboxamide as a novel scaffold for highly potent CC chemokine receptor 2 antagonists.
    Yang L; Butora G; Jiao RX; Pasternak A; Zhou C; Parsons WH; Mills SG; Vicario PP; Ayala JM; Cascieri MA; MacCoss M
    J Med Chem; 2007 May; 50(11):2609-11. PubMed ID: 17461566
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation and structures of novel fungal metabolites as chemokine receptor (CCR2) antagonists.
    Herath KB; Jayasuriya H; Ondeyka JG; Polishook JD; Bills GF; Dombrowski AW; Cabello A; Vicario PP; Zweerink H; Guan Z; Singh SB
    J Antibiot (Tokyo); 2005 Nov; 58(11):686-94. PubMed ID: 16466022
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning and functional characterization of the rabbit C-C chemokine receptor 2.
    Lu D; Yuan XJ; Evans RJ; Pappas AT; Wang H; Su EW; Hamdouchi C; Venkataraman C
    BMC Immunol; 2005 Jul; 6():15. PubMed ID: 16001983
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 4-Azetidinyl-1-heteroatom linked cyclohexane antagonists of CCR2: patent evaluation.
    Horuk R; Guilford W
    Expert Opin Ther Pat; 2011 Aug; 21(8):1275-80. PubMed ID: 21554155
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Assessment of chemokine receptor function on monocytes in whole blood: In vitro and ex vivo evaluations of a CCR2 antagonist.
    Wisniewski T; Bayne E; Flanagan J; Shao Q; Wnek R; Matheravidathu S; Fischer P; Forrest MJ; Peterson L; Song X; Yang L; Demartino JA; Struthers M
    J Immunol Methods; 2010 Jan; 352(1-2):101-10. PubMed ID: 19913021
    [TBL] [Abstract][Full Text] [Related]  

  • 16. N-aryl pyrazoles, indazoles and azaindazoles as antagonists of CC chemokine receptor 1: patent cooperation treaty applications WO2010/036632, WO2009/134666 and WO2009/137338.
    Carter PH; Hynes J
    Expert Opin Ther Pat; 2010 Nov; 20(11):1609-18. PubMed ID: 20858032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Discovery of disubstituted cyclohexanes as a new class of CC chemokine receptor 2 antagonists.
    Cherney RJ; Mo R; Meyer DT; Nelson DJ; Lo YC; Yang G; Scherle PA; Mandlekar S; Wasserman ZR; Jezak H; Solomon KA; Tebben AJ; Carter PH; Decicco CP
    J Med Chem; 2008 Feb; 51(4):721-4. PubMed ID: 18232650
    [TBL] [Abstract][Full Text] [Related]  

  • 18. HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo.
    Han KH; Ryu J; Hong KH; Ko J; Pak YK; Kim JB; Park SW; Kim JJ
    Circulation; 2005 Mar; 111(11):1439-47. PubMed ID: 15781755
    [TBL] [Abstract][Full Text] [Related]  

  • 19. n-Nonanoyl-CCL14 (NNY-CCL14), a novel inhibitor of allergic airway inflammation is a partial agonist of human CCR2.
    Gupta S; Erdmann G; Schulz-Maronde S; Escher SE; Richter R; Forssmann WG; Elsner J; Forssmann U
    Allergy; 2008 Oct; 63(10):1317-23. PubMed ID: 18782110
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Substituted dipiperidine alcohols as potent CCR2 antagonists.
    Xia M; Hou C; Demong D; Pollack S; Pan M; Brackley J; Singer M; Matheis M; Cavender D; Wachter M
    Bioorg Med Chem Lett; 2008 Jun; 18(12):3562-4. PubMed ID: 18487045
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.