BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

120 related articles for article (PubMed ID: 20103661)

  • 1. Mitogen-activated protein/extracellular signal-regulated kinase kinase inhibition results in biphasic alteration of epidermal homeostasis with keratinocytic apoptosis and pigmentation disorders.
    Schad K; Baumann Conzett K; Zipser MC; Enderlin V; Kamarashev J; French LE; Dummer R
    Clin Cancer Res; 2010 Feb; 16(3):1058-64. PubMed ID: 20103661
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of the RAF/mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway mediates apoptosis induced by chelerythrine in osteosarcoma.
    Yang R; Piperdi S; Gorlick R
    Clin Cancer Res; 2008 Oct; 14(20):6396-404. PubMed ID: 18927278
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitogen-activated protein kinase kinase 1/extracellular signal-regulated kinase (MEK-1/ERK) inhibitors sensitize reduced glucocorticoid response mediated by TNFalpha in human epidermal keratinocytes (HaCaT).
    Onda K; Nagashima M; Kawakubo Y; Inoue S; Hirano T; Oka K
    Biochem Biophys Res Commun; 2006 Dec; 351(1):266-72. PubMed ID: 17054908
    [TBL] [Abstract][Full Text] [Related]  

  • 4. AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma.
    Huynh H
    Cancer; 2010 Mar; 116(5):1315-25. PubMed ID: 20101735
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resistance to mitogen-activated protein kinase kinase (MEK) inhibitors correlates with up-regulation of the MEK/extracellular signal-regulated kinase pathway in hepatocellular carcinoma cells.
    Yip-Schneider MT; Klein PJ; Wentz SC; Zeni A; Menze A; Schmidt CM
    J Pharmacol Exp Ther; 2009 Jun; 329(3):1063-70. PubMed ID: 19258520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor.
    Yeh TC; Marsh V; Bernat BA; Ballard J; Colwell H; Evans RJ; Parry J; Smith D; Brandhuber BJ; Gross S; Marlow A; Hurley B; Lyssikatos J; Lee PA; Winkler JD; Koch K; Wallace E
    Clin Cancer Res; 2007 Mar; 13(5):1576-83. PubMed ID: 17332304
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma.
    Panka DJ; Atkins MB; Mier JW
    Clin Cancer Res; 2006 Apr; 12(7 Pt 2):2371s-2375s. PubMed ID: 16609061
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
    Liu L; Cao Y; Chen C; Zhang X; McNabola A; Wilkie D; Wilhelm S; Lynch M; Carter C
    Cancer Res; 2006 Dec; 66(24):11851-8. PubMed ID: 17178882
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two modes of ERK activation by TNF in keratinocytes: different cellular outcomes and bi-directional modulation by vitamin D.
    Ziv E; Rotem C; Miodovnik M; Ravid A; Koren R
    J Cell Biochem; 2008 May; 104(2):606-19. PubMed ID: 18080320
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence.
    Unni E; Sun S; Nan B; McPhaul MJ; Cheskis B; Mancini MA; Marcelli M
    Cancer Res; 2004 Oct; 64(19):7156-68. PubMed ID: 15466214
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Combining nanoliposomal ceramide with sorafenib synergistically inhibits melanoma and breast cancer cell survival to decrease tumor development.
    Tran MA; Smith CD; Kester M; Robertson GP
    Clin Cancer Res; 2008 Jun; 14(11):3571-81. PubMed ID: 18519791
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer.
    Roberts PJ; Der CJ
    Oncogene; 2007 May; 26(22):3291-310. PubMed ID: 17496923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer.
    Banerji U; Camidge DR; Verheul HM; Agarwal R; Sarker D; Kaye SB; Desar IM; Timmer-Bonte JN; Eckhardt SG; Lewis KD; Brown KH; Cantarini MV; Morris C; George SM; Smith PD; van Herpen CM
    Clin Cancer Res; 2010 Mar; 16(5):1613-23. PubMed ID: 20179232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Roles of mitogen activated protein kinases and EGF receptor in arsenite-stimulated matrix metalloproteinase-9 production.
    Cooper KL; Myers TA; Rosenberg M; Chavez M; Hudson LG
    Toxicol Appl Pharmacol; 2004 Nov; 200(3):177-85. PubMed ID: 15504454
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cutaneous drug eruptions associated with the use of new oncological drugs.
    Belloni B; Schönewolf N; Rozati S; Goldinger SM; Dummer R
    Chem Immunol Allergy; 2012; 97():191-202. PubMed ID: 22613863
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protein kinase C zeta mediates epidermal growth factor-induced growth of head and neck tumor cells by regulating mitogen-activated protein kinase.
    Cohen EE; Lingen MW; Zhu B; Zhu H; Straza MW; Pierce C; Martin LE; Rosner MR
    Cancer Res; 2006 Jun; 66(12):6296-303. PubMed ID: 16778206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression and localization of the activated mitogen-activated protein kinase in lesional psoriatic skin.
    Yu XJ; Li CY; Dai HY; Cai DX; Wang KY; Xu YH; Chen LM; Zhou CL
    Exp Mol Pathol; 2007 Dec; 83(3):413-8. PubMed ID: 17599830
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC; Yang CR; Cheng CL; Raung SL; Hung YY; Chen CJ
    Eur J Pharmacol; 2007 Jun; 563(1-3):49-60. PubMed ID: 17341418
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation and role of MAP kinase-dependent pathways in retinal pigment epithelial cells: ERK and RPE cell proliferation.
    Hecquet C; Lefevre G; Valtink M; Engelmann K; Mascarelli F
    Invest Ophthalmol Vis Sci; 2002 Sep; 43(9):3091-8. PubMed ID: 12202534
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p44 mitogen-activated protein kinase (extracellular signal-regulated kinase 1)-dependent signaling contributes to epithelial skin carcinogenesis.
    Bourcier C; Jacquel A; Hess J; Peyrottes I; Angel P; Hofman P; Auberger P; Pouysségur J; Pagès G
    Cancer Res; 2006 Mar; 66(5):2700-7. PubMed ID: 16510590
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.