243 related articles for article (PubMed ID: 20106945)
1. Comparison of HepG2 and HepaRG by whole-genome gene expression analysis for the purpose of chemical hazard identification.
Jennen DG; Magkoufopoulou C; Ketelslegers HB; van Herwijnen MH; Kleinjans JC; van Delft JH
Toxicol Sci; 2010 May; 115(1):66-79. PubMed ID: 20106945
[TBL] [Abstract][Full Text] [Related]
2. Baseline and genotoxic compound induced gene expression profiles in HepG2 and HepaRG compared to primary human hepatocytes.
Jetten MJ; Kleinjans JC; Claessen SM; Chesné C; van Delft JH
Toxicol In Vitro; 2013 Oct; 27(7):2031-40. PubMed ID: 23911569
[TBL] [Abstract][Full Text] [Related]
3. Transcriptomic responses generated by hepatocarcinogens in a battery of liver-based in vitro models.
Doktorova TY; Yildirimman R; Vinken M; Vilardell M; Vanhaecke T; Gmuender H; Bort R; Brolen G; Holmgren G; Li R; Chesne C; van Delft J; Kleinjans J; Castell J; Bjorquist P; Herwig R; Rogiers V
Carcinogenesis; 2013 Jun; 34(6):1393-402. PubMed ID: 23393228
[TBL] [Abstract][Full Text] [Related]
4. Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.
Mathijs K; Brauers KJ; Jennen DG; Boorsma A; van Herwijnen MH; Gottschalk RW; Kleinjans JC; van Delft JH
Toxicol Sci; 2009 Dec; 112(2):374-84. PubMed ID: 19770486
[TBL] [Abstract][Full Text] [Related]
5. Comparison of basal gene expression profiles and effects of hepatocarcinogens on gene expression in cultured primary human hepatocytes and HepG2 cells.
Harris AJ; Dial SL; Casciano DA
Mutat Res; 2004 May; 549(1-2):79-99. PubMed ID: 15120964
[TBL] [Abstract][Full Text] [Related]
6. Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Doktorova TY; Ellinger-Ziegelbauer H; Vinken M; Vanhaecke T; van Delft J; Kleinjans J; Ahr HJ; Rogiers V
Arch Toxicol; 2012 Sep; 86(9):1399-411. PubMed ID: 22484513
[TBL] [Abstract][Full Text] [Related]
7. Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: toxicokinetics is essential for in vivo-in vitro comparisons.
van Kesteren PC; Zwart PE; Schaap MM; Pronk TE; van Herwijnen MH; Kleinjans JC; Bokkers BG; Godschalk RW; Zeilmaker MJ; van Steeg H; Luijten M
Arch Toxicol; 2013 Mar; 87(3):505-15. PubMed ID: 23052197
[TBL] [Abstract][Full Text] [Related]
8. Toxicogenomics applied to in vitro carcinogenicity testing with Balb/c 3T3 cells revealed a gene signature predictive of chemical carcinogens.
Rohrbeck A; Salinas G; Maaser K; Linge J; Salovaara S; Corvi R; Borlak J
Toxicol Sci; 2010 Nov; 118(1):31-41. PubMed ID: 20713471
[TBL] [Abstract][Full Text] [Related]
9. Gene expression profiling in primary mouse hepatocytes discriminates true from false-positive genotoxic compounds.
Mathijs K; Brauers KJ; Jennen DG; Lizarraga D; Kleinjans JC; van Delft JH
Mutagenesis; 2010 Nov; 25(6):561-8. PubMed ID: 20650930
[TBL] [Abstract][Full Text] [Related]
10. Dose- and time-dependent effects of phenobarbital on gene expression profiling in human hepatoma HepaRG cells.
Lambert CB; Spire C; Claude N; Guillouzo A
Toxicol Appl Pharmacol; 2009 Feb; 234(3):345-60. PubMed ID: 19084549
[TBL] [Abstract][Full Text] [Related]
11. Deregulation of cancer-related pathways in primary hepatocytes derived from DNA repair-deficient Xpa-/-p53+/- mice upon exposure to benzo[a]pyrene.
van Kesteren PC; Zwart PE; Pennings JL; Gottschalk WH; Kleinjans JC; van Delft JH; van Steeg H; Luijten M
Toxicol Sci; 2011 Sep; 123(1):123-32. PubMed ID: 21715664
[TBL] [Abstract][Full Text] [Related]
12. Reproducible chemical-induced changes in gene expression profiles in human hepatoma HepaRG cells under various experimental conditions.
Lambert CB; Spire C; Renaud MP; Claude N; Guillouzo A
Toxicol In Vitro; 2009 Apr; 23(3):466-75. PubMed ID: 19159669
[TBL] [Abstract][Full Text] [Related]
13. Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets.
van Delft JH; Mathijs K; Staal YC; van Herwijnen MH; Brauers KJ; Boorsma A; Kleinjans JC
Toxicol Sci; 2010 Oct; 117(2):381-92. PubMed ID: 20624995
[TBL] [Abstract][Full Text] [Related]
14. Modulation of different stress pathways after styrene and styrene-7,8-oxide exposure in HepG2 cell line and normal human hepatocytes.
Diodovich C; Urani C; Maurici D; Malerba I; Melchioretto P; Orlandi M; Zoia L; Campi V; Carfi' M; Pellizzer C; Gribaldo L
J Appl Toxicol; 2006; 26(4):317-25. PubMed ID: 16705669
[TBL] [Abstract][Full Text] [Related]
15. Evaluating microRNA profiles reveals discriminative responses following genotoxic or non-genotoxic carcinogen exposure in primary mouse hepatocytes.
Rieswijk L; Brauers KJ; Coonen ML; van Breda SG; Jennen DG; Kleinjans JC
Mutagenesis; 2015 Nov; 30(6):771-84. PubMed ID: 25976910
[TBL] [Abstract][Full Text] [Related]
16. Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells.
Liguori MJ; Blomme EA; Waring JF
Drug Metab Dispos; 2008 Feb; 36(2):223-33. PubMed ID: 17967932
[TBL] [Abstract][Full Text] [Related]
17. Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.
Hockley SL; Arlt VM; Brewer D; Giddings I; Phillips DH
BMC Genomics; 2006 Oct; 7():260. PubMed ID: 17042939
[TBL] [Abstract][Full Text] [Related]
18. Identification of early target genes of aflatoxin B1 in human hepatocytes, inter-individual variability and comparison with other genotoxic compounds.
Josse R; Dumont J; Fautrel A; Robin MA; Guillouzo A
Toxicol Appl Pharmacol; 2012 Jan; 258(2):176-87. PubMed ID: 22100608
[TBL] [Abstract][Full Text] [Related]
19. NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 2006 Jan; (520):4-246. PubMed ID: 16628245
[TBL] [Abstract][Full Text] [Related]
20. Comparison of supervised clustering methods to discriminate genotoxic from non-genotoxic carcinogens by gene expression profiling.
van Delft JH; van Agen E; van Breda SG; Herwijnen MH; Staal YC; Kleinjans JC
Mutat Res; 2005 Aug; 575(1-2):17-33. PubMed ID: 15924884
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]