196 related articles for article (PubMed ID: 20106946)
21. An evaluation of the mode of action framework for mutagenic carcinogens case study: Cyclophosphamide.
McCarroll N; Keshava N; Cimino M; Chu M; Dearfield K; Keshava C; Kligerman A; Owen R; Protzel A; Putzrath R; Schoeny R
Environ Mol Mutagen; 2008 Mar; 49(2):117-31. PubMed ID: 18240158
[TBL] [Abstract][Full Text] [Related]
22. Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
Cruzan G; Bus J; Banton M; Gingell R; Carlson G
Regul Toxicol Pharmacol; 2009 Nov; 55(2):205-18. PubMed ID: 19589367
[TBL] [Abstract][Full Text] [Related]
23. NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1993 Sep; 422():1-340. PubMed ID: 12616289
[TBL] [Abstract][Full Text] [Related]
24. NTP Toxicology and Carcinogenesis Studies of Methyleugenol (CAS NO. 93-15-2) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 2000 Jul; 491():1-412. PubMed ID: 12563349
[TBL] [Abstract][Full Text] [Related]
25. Toxicogenomics and cancer risk assessment: a framework for key event analysis and dose-response assessment for nongenotoxic carcinogens.
Bercu JP; Jolly RA; Flagella KM; Baker TK; Romero P; Stevens JL
Regul Toxicol Pharmacol; 2010 Dec; 58(3):369-81. PubMed ID: 20801182
[TBL] [Abstract][Full Text] [Related]
26. Metabolism of chloroform by cytochrome P450 2E1 is required for induction of toxicity in the liver, kidney, and nose of male mice.
Constan AA; Sprankle CS; Peters JM; Kedderis GL; Everitt JI; Wong BA; Gonzalez FL; Butterworth BE
Toxicol Appl Pharmacol; 1999 Oct; 160(2):120-6. PubMed ID: 10527910
[TBL] [Abstract][Full Text] [Related]
27. NTP toxicology and carcinogenesis studies of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (CAS No. 57465-28-8) in female Harlan Sprague-Dawley rats (Gavage Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 2006 Jan; (520):4-246. PubMed ID: 16628245
[TBL] [Abstract][Full Text] [Related]
28. NTP Toxicology and Carcinogenesis Studies of C.I. Direct Blue 218 (CAS No. 28407-37-6) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1994 Feb; 430():1-280. PubMed ID: 12616301
[TBL] [Abstract][Full Text] [Related]
29. Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver.
Ellinger-Ziegelbauer H; Stuart B; Wahle B; Bomann W; Ahr HJ
Mutat Res; 2005 Aug; 575(1-2):61-84. PubMed ID: 15890375
[TBL] [Abstract][Full Text] [Related]
30. Hemangiosarcoma in rodents: mode-of-action evaluation and human relevance.
Cohen SM; Storer RD; Criswell KA; Doerrer NG; Dellarco VL; Pegg DG; Wojcinski ZW; Malarkey DE; Jacobs AC; Klaunig JE; Swenberg JA; Cook JC
Toxicol Sci; 2009 Sep; 111(1):4-18. PubMed ID: 19525443
[TBL] [Abstract][Full Text] [Related]
31. Evaluating genotoxicity data to identify a mode of action and its application in estimating cancer risk at low doses: A case study involving carbon tetrachloride.
Eastmond DA
Environ Mol Mutagen; 2008 Mar; 49(2):132-41. PubMed ID: 18213651
[TBL] [Abstract][Full Text] [Related]
32. Chloroform-induced cytolethality in freshly isolated male B6C3F1 mouse and F-344 rat hepatocytes.
Ammann P; Laethem CL; Kedderis GL
Toxicol Appl Pharmacol; 1998 Apr; 149(2):217-25. PubMed ID: 9571991
[TBL] [Abstract][Full Text] [Related]
33. Toxicology and Carcinogenesis Studies of Mercuric Chloride (CAS No. 7487-94-7) in F344 Rats and B6C3F1 Mice (Gavage Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1993 Feb; 408():1-260. PubMed ID: 12621522
[TBL] [Abstract][Full Text] [Related]
34. The utility of PBPK in the safety assessment of chloroform and carbon tetrachloride.
Delic JI; Lilly PD; MacDonald AJ; Loizou GD
Regul Toxicol Pharmacol; 2000 Oct; 32(2):144-55. PubMed ID: 11067771
[TBL] [Abstract][Full Text] [Related]
35. Mode of action considerations in the quantitative assessment of tumour responses in the liver.
Boobis AR
Basic Clin Pharmacol Toxicol; 2010 Mar; 106(3):173-9. PubMed ID: 20030633
[TBL] [Abstract][Full Text] [Related]
36. NTP Toxicology and Carcinogenesis Studies of Pentachloroanisole (CAS No. 1825-21-4) in F344 Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1993 Apr; 414():1-284. PubMed ID: 12616284
[TBL] [Abstract][Full Text] [Related]
37. Difficulty of mode of action determination for trichloroethylene: An example of complex interactions of metabolites and other chemical exposures.
Caldwell JC; Keshava N; Evans MV
Environ Mol Mutagen; 2008 Mar; 49(2):142-54. PubMed ID: 17973308
[TBL] [Abstract][Full Text] [Related]
38. NTP Toxicology and Carcinogenesis Studies of 1-Amino-2,4-Dibromoanthraquinone (CAS No. 81-49-2) in F344/N Rats and B6C3F1 Mice (Feed Studies).
National Toxicology Program
Natl Toxicol Program Tech Rep Ser; 1996 Aug; 383():1-370. PubMed ID: 12692653
[TBL] [Abstract][Full Text] [Related]
39. Genotoxicity of 1,3-butadiene and its epoxy intermediates.
Walker VE; Walker DM; Meng Q; McDonald JD; Scott BR; Seilkop SK; Claffey DJ; Upton PB; Powley MW; Swenberg JA; Henderson RF;
Res Rep Health Eff Inst; 2009 Aug; (144):3-79. PubMed ID: 20017413
[TBL] [Abstract][Full Text] [Related]
40. PBPK models in risk assessment--A focus on chloroprene.
DeWoskin RS
Chem Biol Interact; 2007 Mar; 166(1-3):352-9. PubMed ID: 17324392
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
