319 related articles for article (PubMed ID: 20107862)
1. Microtubule targeting agents: from biophysics to proteomics.
Calligaris D; Verdier-Pinard P; Devred F; Villard C; Braguer D; Lafitte D
Cell Mol Life Sci; 2010 Apr; 67(7):1089-104. PubMed ID: 20107862
[TBL] [Abstract][Full Text] [Related]
2. The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization.
Prota AE; Danel F; Bachmann F; Bargsten K; Buey RM; Pohlmann J; Reinelt S; Lane H; Steinmetz MO
J Mol Biol; 2014 Apr; 426(8):1848-60. PubMed ID: 24530796
[TBL] [Abstract][Full Text] [Related]
3. Structural comparison of the interaction of tubulin with various ligands affecting microtubule dynamics.
Stec-Martyna E; Ponassi M; Miele M; Parodi S; Felli L; Rosano C
Curr Cancer Drug Targets; 2012 Jul; 12(6):658-66. PubMed ID: 22385515
[TBL] [Abstract][Full Text] [Related]
4. Microtubule Targeting Agents as Cancer Chemotherapeutics: An Overview of Molecular Hybrids as Stabilizing and Destabilizing Agents.
Tangutur AD; Kumar D; Krishna KV; Kantevari S
Curr Top Med Chem; 2017; 17(22):2523-2537. PubMed ID: 28056738
[TBL] [Abstract][Full Text] [Related]
5. What tubulin drugs tell us about microtubule structure and dynamics.
Amos LA
Semin Cell Dev Biol; 2011 Dec; 22(9):916-26. PubMed ID: 22001382
[TBL] [Abstract][Full Text] [Related]
6. Novel fragment-derived colchicine-site binders as microtubule-destabilizing agents.
de la Roche NM; Mühlethaler T; Di Martino RMC; Ortega JA; Gioia D; Roy B; Prota AE; Steinmetz MO; Cavalli A
Eur J Med Chem; 2022 Nov; 241():114614. PubMed ID: 35939994
[TBL] [Abstract][Full Text] [Related]
7. Discovery of potent microtubule-destabilizing agents targeting for colchicine site by virtual screening, biological evaluation, and molecular dynamics simulation.
Zhang H; Luo QQ; Hu ML; Wang N; Qi HZ; Zhang HR; Ding L
Eur J Pharm Sci; 2023 Jan; 180():106340. PubMed ID: 36435355
[TBL] [Abstract][Full Text] [Related]
8. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
Ma Y; Fang S; Li H; Han C; Lu Y; Zhao Y; Liu Y; Zhao C
Chem Biol Drug Des; 2013 Jul; 82(1):12-21. PubMed ID: 23786349
[TBL] [Abstract][Full Text] [Related]
9. The Unique Binding Mode of Laulimalide to Two Tubulin Protofilaments.
Churchill CD; Klobukowski M; Tuszynski JA
Chem Biol Drug Des; 2015 Aug; 86(2):190-9. PubMed ID: 25376845
[TBL] [Abstract][Full Text] [Related]
10. Tools for the rational design of bivalent microtubule-targeting drugs.
Marangon J; Christodoulou MS; Casagrande FV; Tiana G; Dalla Via L; Aliverti A; Passarella D; Cappelletti G; Ricagno S
Biochem Biophys Res Commun; 2016 Oct; 479(1):48-53. PubMed ID: 27613098
[TBL] [Abstract][Full Text] [Related]
11. Molecular dynamics simulation and free energy landscape methods in probing L215H, L217R and L225M βI-tubulin mutations causing paclitaxel resistance in cancer cells.
Tripathi S; Srivastava G; Sharma A
Biochem Biophys Res Commun; 2016 Aug; 476(4):273-279. PubMed ID: 27233604
[TBL] [Abstract][Full Text] [Related]
12. Structural insight into the role of Gln293Met mutation on the Peloruside A/Laulimalide association with αβ-tubulin from molecular dynamics simulations, binding free energy calculations and weak interactions analysis.
Zúñiga MA; Alderete JB; Jaña GA; Jiménez VA
J Comput Aided Mol Des; 2017 Jul; 31(7):643-652. PubMed ID: 28597356
[TBL] [Abstract][Full Text] [Related]
13. Unravelling the covalent binding of zampanolide and taccalonolide AJ to a minimalist representation of a human microtubule.
Sánchez-Murcia PA; Mills A; Cortés-Cabrera Á; Gago F
J Comput Aided Mol Des; 2019 Jul; 33(7):627-644. PubMed ID: 31152293
[TBL] [Abstract][Full Text] [Related]
14. Similarity-based virtual screening for microtubule stabilizers reveals novel antimitotic scaffold.
Ayoub AT; Klobukowski M; Tuszynski J
J Mol Graph Model; 2013 Jul; 44():188-96. PubMed ID: 23871820
[TBL] [Abstract][Full Text] [Related]
15. Dissecting paclitaxel-microtubule association: quantitative assessment of the 2'-OH group.
Sharma S; Lagisetti C; Poliks B; Coates RM; Kingston DG; Bane S
Biochemistry; 2013 Apr; 52(13):2328-36. PubMed ID: 23473345
[TBL] [Abstract][Full Text] [Related]
16. Recent advances in research of colchicine binding site inhibitors and their interaction modes with tubulin.
Sun K; Sun Z; Zhao F; Shan G; Meng Q
Future Med Chem; 2021 May; 13(9):839-858. PubMed ID: 33821673
[TBL] [Abstract][Full Text] [Related]
17. Discovery of novel microtubule stabilizers targeting taxane binding site by applying molecular docking, molecular dynamics simulation, and anticancer activity testing.
Zhang H; Qi HZ; Mao J; Zhang HR; Luo QQ; Hu ML; Shen C; Ding L
Bioorg Chem; 2022 May; 122():105722. PubMed ID: 35303622
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and anticancer activity of analogues of phenstatin, with a phenothiazine A-ring, as a new class of microtubule-targeting agents.
Abuhaie CM; Bîcu E; Rigo B; Gautret P; Belei D; Farce A; Dubois J; Ghinet A
Bioorg Med Chem Lett; 2013 Jan; 23(1):147-52. PubMed ID: 23200248
[TBL] [Abstract][Full Text] [Related]
19. A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Prota AE; Bargsten K; Diaz JF; Marsh M; Cuevas C; Liniger M; Neuhaus C; Andreu JM; Altmann KH; Steinmetz MO
Proc Natl Acad Sci U S A; 2014 Sep; 111(38):13817-21. PubMed ID: 25114240
[TBL] [Abstract][Full Text] [Related]
20. Distinct pose of discodermolide in taxol binding pocket drives a complementary mode of microtubule stabilization.
Khrapunovich-Baine M; Menon V; Verdier-Pinard P; Smith AB; Angeletti RH; Fiser A; Horwitz SB; Xiao H
Biochemistry; 2009 Dec; 48(49):11664-77. PubMed ID: 19863156
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
