These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

484 related articles for article (PubMed ID: 20111001)

  • 1. Hsp70 stabilizes lysosomes and reverts Niemann-Pick disease-associated lysosomal pathology.
    Kirkegaard T; Roth AG; Petersen NH; Mahalka AK; Olsen OD; Moilanen I; Zylicz A; Knudsen J; Sandhoff K; Arenz C; Kinnunen PK; Nylandsted J; Jäättelä M
    Nature; 2010 Jan; 463(7280):549-53. PubMed ID: 20111001
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Connecting Hsp70, sphingolipid metabolism and lysosomal stability.
    Petersen NH; Kirkegaard T; Olsen OD; Jäättelä M
    Cell Cycle; 2010 Jun; 9(12):2305-9. PubMed ID: 20519957
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heat shock protein 70.1 (Hsp70.1) affects neuronal cell fate by regulating lysosomal acid sphingomyelinase.
    Zhu H; Yoshimoto T; Yamashima T
    J Biol Chem; 2014 Oct; 289(40):27432-43. PubMed ID: 25074941
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational dynamics of free and membrane-bound human Hsp70 in model cytosolic and endo-lysosomal environments.
    Calvaresi V; Truelsen LT; Larsen SB; Petersen NHT; Kirkegaard T; Rand KD
    Commun Biol; 2021 Dec; 4(1):1369. PubMed ID: 34876699
    [TBL] [Abstract][Full Text] [Related]  

  • 5. HSP70 and lysosomal storage disorders: novel therapeutic opportunities.
    Petersen NH; Kirkegaard T
    Biochem Soc Trans; 2010 Dec; 38(6):1479-83. PubMed ID: 21118111
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Intracerebral transplantation of adult mouse neural progenitor cells into the Niemann-Pick-A mouse leads to a marked decrease in lysosomal storage pathology.
    Shihabuddin LS; Numan S; Huff MR; Dodge JC; Clarke J; Macauley SL; Yang W; Taksir TV; Parsons G; Passini MA; Gage FH; Stewart GR
    J Neurosci; 2004 Nov; 24(47):10642-51. PubMed ID: 15564580
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeting lysosomal HSP70 induces acid sphingomyelinase-mediated disturbance of lipid metabolism and leads to cell death in T cell malignancies.
    Qing Y; Guo Y; Zhao Q; Hu P; Li H; Yu X; Zhu M; Wang H; Wang Z; Xu J; Guo Q; Hui H
    Clin Transl Med; 2023 Mar; 13(3):e1229. PubMed ID: 36959764
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase.
    Petersen NH; Olsen OD; Groth-Pedersen L; Ellegaard AM; Bilgin M; Redmer S; Ostenfeld MS; Ulanet D; Dovmark TH; Lønborg A; Vindeløv SD; Hanahan D; Arenz C; Ejsing CS; Kirkegaard T; Rohde M; Nylandsted J; Jäättelä M
    Cancer Cell; 2013 Sep; 24(3):379-93. PubMed ID: 24029234
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Massive Accumulation of Sphingomyelin Affects the Lysosomal and Mitochondria Compartments and Promotes Apoptosis in Niemann-Pick Disease Type A.
    Carsana EV; Lunghi G; Prioni S; Mauri L; Loberto N; Prinetti A; Zucca FA; Bassi R; Sonnino S; Chiricozzi E; Duga S; Straniero L; Asselta R; Soldà G; Samarani M; Aureli M
    J Mol Neurosci; 2022 Jul; 72(7):1482-1499. PubMed ID: 35727525
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spectrum of SMPD1 mutations in Asian-Indian patients with acid sphingomyelinase (ASM)-deficient Niemann-Pick disease.
    Ranganath P; Matta D; Bhavani GS; Wangnekar S; Jain JM; Verma IC; Kabra M; Puri RD; Danda S; Gupta N; Girisha KM; Sankar VH; Patil SJ; Ramadevi AR; Bhat M; Gowrishankar K; Mandal K; Aggarwal S; Tamhankar PM; Tilak P; Phadke SR; Dalal A
    Am J Med Genet A; 2016 Oct; 170(10):2719-30. PubMed ID: 27338287
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells.
    Suchi M; Dinur T; Desnick RJ; Gatt S; Pereira L; Gilboa E; Schuchman EH
    Proc Natl Acad Sci U S A; 1992 Apr; 89(8):3227-31. PubMed ID: 1565614
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway.
    Levade T; Vidal F; Vermeersch S; Andrieu N; Gatt S; Salvayre R
    Biochim Biophys Acta; 1995 Oct; 1258(3):277-87. PubMed ID: 7548198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A.
    Long Y; Xu M; Li R; Dai S; Beers J; Chen G; Soheilian F; Baxa U; Wang M; Marugan JJ; Muro S; Li Z; Brady R; Zheng W
    Stem Cells Transl Med; 2016 Dec; 5(12):1644-1655. PubMed ID: 27484861
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clathrin-mediated endocytosis is impaired in type A-B Niemann-Pick disease model cells and can be restored by ICAM-1-mediated enzyme replacement.
    Rappaport J; Garnacho C; Muro S
    Mol Pharm; 2014 Aug; 11(8):2887-95. PubMed ID: 24949999
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Lysosomal enzyme delivery by ICAM-1-targeted nanocarriers bypassing glycosylation- and clathrin-dependent endocytosis.
    Muro S; Schuchman EH; Muzykantov VR
    Mol Ther; 2006 Jan; 13(1):135-41. PubMed ID: 16153895
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improvement in lipid and protein trafficking in Niemann-Pick C1 cells by correction of a secondary enzyme defect.
    Devlin C; Pipalia NH; Liao X; Schuchman EH; Maxfield FR; Tabas I
    Traffic; 2010 May; 11(5):601-15. PubMed ID: 20412078
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase.
    Abdul-Hammed M; Breiden B; Schwarzmann G; Sandhoff K
    J Lipid Res; 2017 Mar; 58(3):563-577. PubMed ID: 28126847
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of the sphingomyelin phosphodiesterase 1 gene (SMPD1) in Turkish Niemann-Pick disease patients: mutation profile and description of a novel mutation.
    Aykut A; Karaca E; Onay H; Ucar SK; Coker M; Cogulu O; Ozkinay F
    Gene; 2013 Sep; 526(2):484-6. PubMed ID: 23618813
    [TBL] [Abstract][Full Text] [Related]  

  • 19. AAV vector-mediated correction of brain pathology in a mouse model of Niemann-Pick A disease.
    Passini MA; Macauley SL; Huff MR; Taksir TV; Bu J; Wu IH; Piepenhagen PA; Dodge JC; Shihabuddin LS; O'Riordan CR; Schuchman EH; Stewart GR
    Mol Ther; 2005 May; 11(5):754-62. PubMed ID: 15851014
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Accurate differentiation of neuronopathic and nonneuronopathic forms of Niemann-Pick disease by evaluation of the effective residual lysosomal sphingomyelinase activity in intact cells.
    Graber D; Salvayre R; Levade T
    J Neurochem; 1994 Sep; 63(3):1060-8. PubMed ID: 8051547
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.