287 related articles for article (PubMed ID: 20117093)
1. Down-regulation of Notch1 by gamma-secretase inhibition contributes to cell growth inhibition and apoptosis in ovarian cancer cells A2780.
Wang M; Wu L; Wang L; Xin X
Biochem Biophys Res Commun; 2010 Feb; 393(1):144-9. PubMed ID: 20117093
[TBL] [Abstract][Full Text] [Related]
2. Pretreatment with the γ-secretase inhibitor DAPT sensitizes drug-resistant ovarian cancer cells to cisplatin by downregulation of Notch signaling.
Wang M; Ma X; Wang J; Wang L; Wang Y
Int J Oncol; 2014 Apr; 44(4):1401-9. PubMed ID: 24535252
[TBL] [Abstract][Full Text] [Related]
3. Sequential combination therapy of ovarian cancer with cisplatin and γ-secretase inhibitor MK-0752.
Chen X; Gong L; Ou R; Zheng Z; Chen J; Xie F; Huang X; Qiu J; Zhang W; Jiang Q; Yang Y; Zhu H; Shi Z; Yan X
Gynecol Oncol; 2016 Mar; 140(3):537-44. PubMed ID: 26704638
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of gamma-secretase in Notch1 signaling pathway as a novel treatment for ovarian cancer.
Feng Z; Xu W; Zhang C; Liu M; Wen H
Oncotarget; 2017 Jan; 8(5):8215-8225. PubMed ID: 28030808
[TBL] [Abstract][Full Text] [Related]
5. Effects of N-[N-(3, 5-difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester (DAPT) on cell proliferation and apoptosis in Ishikawa endometrial cancer cells.
Mori M; Miyamoto T; Yakushiji H; Ohno S; Miyake Y; Sakaguchi T; Hattori M; Hongo A; Nakaizumi A; Ueda M; Ohno E
Hum Cell; 2012 Mar; 25(1):9-15. PubMed ID: 22189483
[TBL] [Abstract][Full Text] [Related]
6. [Expression of Notch1, Jagged1 and NICD in epithelial ovarian carcinomas and a preliminary study on the activity of gamma-secretase in epithelial ovarian carcinoma cell lines].
Feng Z; Wen H; Liao Q
Zhonghua Fu Chan Ke Za Zhi; 2014 Oct; 49(10):780-6. PubMed ID: 25537253
[TBL] [Abstract][Full Text] [Related]
7. [Notch signaling pathway blocked by gamma-secretase inhibitor and its effect on the growth and apoptosis of SKOV3 cells].
Lu YL; Xie C
Sichuan Da Xue Xue Bao Yi Xue Ban; 2014 Jul; 45(4):578-81, 611. PubMed ID: 25286679
[TBL] [Abstract][Full Text] [Related]
8. The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway.
Zhang H; Ye Y; Bai Z; Wang S
Dig Dis Sci; 2008 Aug; 53(8):2195-203. PubMed ID: 18320325
[TBL] [Abstract][Full Text] [Related]
9. [Effects of gamma-secretase inhibitor N-(3, 5-difluorophenacetyl-L-alanyl)-S-phenylglycine t-butyl ester on proliferation and differentiation of neural stem cells].
Cai LZ; Lin L; Hu JS; Zheng ZH
Zhonghua Yi Xue Za Zhi; 2008 Feb; 88(7):480-3. PubMed ID: 18642791
[TBL] [Abstract][Full Text] [Related]
10. [Effect of DAPT on proliferation and apoptosis of human multiple myeloma cell line RPMI8226].
Yuan YY; Zeng ZY; Chen JM
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2012 Aug; 20(4):922-5. PubMed ID: 22931655
[TBL] [Abstract][Full Text] [Related]
11. Inhibition of Notch signaling pathway using γ-secretase inhibitor delivered by a low dose of Triton-X100 in cultured oral cancer cells.
Nasrin A; Hassan M; Ye P
Biochem Biophys Res Commun; 2018 Jan; 495(3):2118-2124. PubMed ID: 29253571
[TBL] [Abstract][Full Text] [Related]
12. Enhanced angiogenesis promoted by human umbilical mesenchymal stem cell transplantation in stroked mouse is Notch1 signaling associated.
Zhu J; Liu Q; Jiang Y; Wu L; Xu G; Liu X
Neuroscience; 2015 Apr; 290():288-99. PubMed ID: 25637797
[TBL] [Abstract][Full Text] [Related]
13. [Expression of Notch intracellular domain in cervical cancer and effect of DAPT on cervical cancer cell].
Sun XM; Wen HW; Chen CL; Liao QP
Zhonghua Fu Chan Ke Za Zhi; 2009 May; 44(5):369-73. PubMed ID: 19573314
[TBL] [Abstract][Full Text] [Related]
14. [Expression of Notch3 and Notch intracellular domain in ovarian carcinoma and effect of N-[N-(3,5-difluorophenyl) acetyl-L-alanyl]-S-phenyl glycine t-butyl ester on ovarian carcinoma cell].
Ma K; Wen HW; Liao QP
Zhonghua Fu Chan Ke Za Zhi; 2010 Dec; 45(12):921-6. PubMed ID: 21211425
[TBL] [Abstract][Full Text] [Related]
15. Antiproliferative effects of γ-secretase inhibitor, a Notch signalling inhibitor, in multiple myeloma cells and its molecular mechanism of action.
Hu J; Zhu X; Lu Q
J Int Med Res; 2013 Aug; 41(4):1017-26. PubMed ID: 23839278
[TBL] [Abstract][Full Text] [Related]
16. Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Yang T; Arslanova D; Gu Y; Augelli-Szafran C; Xia W
Mol Brain; 2008 Nov; 1():15. PubMed ID: 18983676
[TBL] [Abstract][Full Text] [Related]
17. In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia.
De Keersmaecker K; Lahortiga I; Mentens N; Folens C; Van Neste L; Bekaert S; Vandenberghe P; Odero MD; Marynen P; Cools J
Haematologica; 2008 Apr; 93(4):533-42. PubMed ID: 18322257
[TBL] [Abstract][Full Text] [Related]
18. Inhibition of gamma-secretases alters both proliferation and differentiation of mesenchymal stem cells.
Vujovic S; Henderson SR; Flanagan AM; Clements MO
Cell Prolif; 2007 Apr; 40(2):185-95. PubMed ID: 17472726
[TBL] [Abstract][Full Text] [Related]
19. Xanthohumol decreases Notch1 expression and cell growth by cell cycle arrest and induction of apoptosis in epithelial ovarian cancer cell lines.
Drenzek JG; Seiler NL; Jaskula-Sztul R; Rausch MM; Rose SL
Gynecol Oncol; 2011 Aug; 122(2):396-401. PubMed ID: 21616523
[TBL] [Abstract][Full Text] [Related]
20. DAPT enhances the apoptosis of human tongue carcinoma cells.
Grottkau BE; Chen XR; Friedrich CC; Yang XM; Jing W; Wu Y; Cai XX; Liu YR; Huang YD; Lin YF
Int J Oral Sci; 2009 Jun; 1(2):81-9. PubMed ID: 20687300
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]