BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

744 related articles for article (PubMed ID: 20118229)

  • 1. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH; Lin L; Zhang X; Nguyen TA; Darlington Y; Waldman AS; Lu X; Donehower LA
    J Biol Chem; 2010 Apr; 285(17):12935-47. PubMed ID: 20118229
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.
    Moon SH; Nguyen TA; Darlington Y; Lu X; Donehower LA
    Cell Cycle; 2010 Jun; 9(11):2092-6. PubMed ID: 20495376
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX.
    Douglas P; Zhong J; Ye R; Moorhead GB; Xu X; Lees-Miller SP
    Mol Cell Biol; 2010 Mar; 30(6):1368-81. PubMed ID: 20065038
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Carcinogenic bacterial pathogen Helicobacter pylori triggers DNA double-strand breaks and a DNA damage response in its host cells.
    Toller IM; Neelsen KJ; Steger M; Hartung ML; Hottiger MO; Stucki M; Kalali B; Gerhard M; Sartori AA; Lopes M; Müller A
    Proc Natl Acad Sci U S A; 2011 Sep; 108(36):14944-9. PubMed ID: 21896770
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.
    Neumayer G; Helfricht A; Shim SY; Le HT; Lundin C; Belzil C; Chansard M; Yu Y; Lees-Miller SP; Gruss OJ; van Attikum H; Helleday T; Nguyen MD
    J Biol Chem; 2012 Dec; 287(50):42206-22. PubMed ID: 23045526
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.
    Macůrek L; Lindqvist A; Voets O; Kool J; Vos HR; Medema RH
    Oncogene; 2010 Apr; 29(15):2281-91. PubMed ID: 20101220
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling.
    Yamauchi M; Oka Y; Yamamoto M; Niimura K; Uchida M; Kodama S; Watanabe M; Sekine I; Yamashita S; Suzuki K
    DNA Repair (Amst); 2008 Mar; 7(3):405-17. PubMed ID: 18248856
    [TBL] [Abstract][Full Text] [Related]  

  • 8. gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.
    Chowdhury D; Keogh MC; Ishii H; Peterson CL; Buratowski S; Lieberman J
    Mol Cell; 2005 Dec; 20(5):801-9. PubMed ID: 16310392
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells.
    Oh KS; Bustin M; Mazur SJ; Appella E; Kraemer KH
    DNA Repair (Amst); 2011 Jan; 10(1):5-15. PubMed ID: 20947453
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin.
    Savic V; Yin B; Maas NL; Bredemeyer AL; Carpenter AC; Helmink BA; Yang-Iott KS; Sleckman BP; Bassing CH
    Mol Cell; 2009 May; 34(3):298-310. PubMed ID: 19450528
    [TBL] [Abstract][Full Text] [Related]  

  • 11. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MDC1 is a mediator of the mammalian DNA damage checkpoint.
    Stewart GS; Wang B; Bignell CR; Taylor AM; Elledge SJ
    Nature; 2003 Feb; 421(6926):961-6. PubMed ID: 12607005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA damage signaling in response to double-strand breaks during mitosis.
    Giunta S; Belotserkovskaya R; Jackson SP
    J Cell Biol; 2010 Jul; 190(2):197-207. PubMed ID: 20660628
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Clustered DNA damage induces pan-nuclear H2AX phosphorylation mediated by ATM and DNA-PK.
    Meyer B; Voss KO; Tobias F; Jakob B; Durante M; Taucher-Scholz G
    Nucleic Acids Res; 2013 Jul; 41(12):6109-18. PubMed ID: 23620287
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.
    Noon AT; Shibata A; Rief N; Löbrich M; Stewart GS; Jeggo PA; Goodarzi AA
    Nat Cell Biol; 2010 Feb; 12(2):177-84. PubMed ID: 20081839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J; Ferguson D; Song H; Bassing C; Eckersdorff M; Alt FW; Xu Y
    Mol Cell Biol; 2005 Jan; 25(2):661-70. PubMed ID: 15632067
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PTIP regulates 53BP1 and SMC1 at the DNA damage sites.
    Wu J; Prindle MJ; Dressler GR; Yu X
    J Biol Chem; 2009 Jul; 284(27):18078-84. PubMed ID: 19414588
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ataxia telangiectasia mutated activation by transcription- and topoisomerase I-induced DNA double-strand breaks.
    Sordet O; Redon CE; Guirouilh-Barbat J; Smith S; Solier S; Douarre C; Conti C; Nakamura AJ; Das BB; Nicolas E; Kohn KW; Bonner WM; Pommier Y
    EMBO Rep; 2009 Aug; 10(8):887-93. PubMed ID: 19557000
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response.
    Cha H; Lowe JM; Li H; Lee JS; Belova GI; Bulavin DV; Fornace AJ
    Cancer Res; 2010 May; 70(10):4112-22. PubMed ID: 20460517
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nucleotide excision repair-dependent DNA double-strand break formation and ATM signaling activation in mammalian quiescent cells.
    Wakasugi M; Sasaki T; Matsumoto M; Nagaoka M; Inoue K; Inobe M; Horibata K; Tanaka K; Matsunaga T
    J Biol Chem; 2014 Oct; 289(41):28730-7. PubMed ID: 25164823
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 38.