BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 20122908)

  • 1. Lactonases with organophosphatase activity: structural and evolutionary perspectives.
    Draganov DI
    Chem Biol Interact; 2010 Sep; 187(1-3):370-2. PubMed ID: 20122908
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The latent promiscuity of newly identified microbial lactonases is linked to a recently diverged phosphotriesterase.
    Afriat L; Roodveldt C; Manco G; Tawfik DS
    Biochemistry; 2006 Nov; 45(46):13677-86. PubMed ID: 17105187
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Shared promiscuous activities and evolutionary features in various members of the amidohydrolase superfamily.
    Roodveldt C; Tawfik DS
    Biochemistry; 2005 Sep; 44(38):12728-36. PubMed ID: 16171387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hyperthermophilic phosphotriesterases/lactonases for the environment and human health.
    Mandrich L; Merone L; Manco G
    Environ Technol; 2010 Sep; 31(10):1115-27. PubMed ID: 20718294
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstructing a missing link in the evolution of a recently diverged phosphotriesterase by active-site loop remodeling.
    Afriat-Jurnou L; Jackson CJ; Tawfik DS
    Biochemistry; 2012 Aug; 51(31):6047-55. PubMed ID: 22809311
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes.
    Harel M; Aharoni A; Gaidukov L; Brumshtein B; Khersonsky O; Meged R; Dvir H; Ravelli RB; McCarthy A; Toker L; Silman I; Sussman JL; Tawfik DS
    Nat Struct Mol Biol; 2004 May; 11(5):412-9. PubMed ID: 15098021
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural characterization of the catalytic calcium-binding site in diisopropyl fluorophosphatase (DFPase)--comparison with related beta-propeller enzymes.
    Blum MM; Chen JC
    Chem Biol Interact; 2010 Sep; 187(1-3):373-9. PubMed ID: 20206152
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase.
    Khersonsky O; Tawfik DS
    Biochemistry; 2005 Apr; 44(16):6371-82. PubMed ID: 15835926
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase.
    Mandrich L; Manco G
    Biochemistry; 2009 Jun; 48(24):5602-12. PubMed ID: 19438255
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new phosphotriesterase from Sulfolobus acidocaldarius and its comparison with the homologue from Sulfolobus solfataricus.
    Porzio E; Merone L; Mandrich L; Rossi M; Manco G
    Biochimie; 2007 May; 89(5):625-36. PubMed ID: 17337320
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Senescence marker protein-30 is a unique enzyme that hydrolyzes diisopropyl phosphorofluoridate in the liver.
    Kondo Y; Ishigami A; Kubo S; Handa S; Gomi K; Hirokawa K; Kajiyama N; Chiba T; Shimokado K; Maruyama N
    FEBS Lett; 2004 Jul; 570(1-3):57-62. PubMed ID: 15251439
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Differences in amino acid residues in the binding pockets dictate substrate specificities of mouse senescence marker protein-30, human paraoxonase1, and squid diisopropylfluorophosphatase.
    Belinskaya T; Pattabiraman N; diTargiani R; Choi M; Saxena A
    Biochim Biophys Acta; 2012 May; 1824(5):701-10. PubMed ID: 22401958
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of human paraoxonase 1 variants suggest that His residues at 115 and 134 positions are not always needed for the lactonase/arylesterase activities of the enzyme.
    Bajaj P; Tripathy RK; Aggarwal G; Pande AH
    Protein Sci; 2013 Dec; 22(12):1799-807. PubMed ID: 24123308
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for natural lactonase and promiscuous phosphotriesterase activities.
    Elias M; Dupuy J; Merone L; Mandrich L; Porzio E; Moniot S; Rochu D; Lecomte C; Rossi M; Masson P; Manco G; Chabriere E
    J Mol Biol; 2008 Jun; 379(5):1017-28. PubMed ID: 18486146
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp.
    Luo XJ; Kong XD; Zhao J; Chen Q; Zhou J; Xu JH
    Biotechnol Bioeng; 2014 Oct; 111(10):1920-30. PubMed ID: 24771278
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Directed evolution of a quorum-quenching lactonase from Mycobacterium avium subsp. paratuberculosis K-10 in the amidohydrolase superfamily.
    Chow JY; Wu L; Yew WS
    Biochemistry; 2009 May; 48(20):4344-53. PubMed ID: 19374350
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1.
    Blaha-Nelson D; Krüger DM; Szeler K; Ben-David M; Kamerlin SC
    J Am Chem Soc; 2017 Jan; 139(3):1155-1167. PubMed ID: 28026940
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model.
    Yeung DT; Josse D; Nicholson JD; Khanal A; McAndrew CW; Bahnson BJ; Lenz DE; Cerasoli DM
    Biochim Biophys Acta; 2004 Oct; 1702(1):67-77. PubMed ID: 15450851
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity.
    diTargiani RC; Chandrasekaran L; Belinskaya T; Saxena A
    Chem Biol Interact; 2010 Sep; 187(1-3):349-54. PubMed ID: 20176006
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Update on biochemical properties of recombinant Pseudomonas diminuta phosphotriesterase.
    Carletti E; Jacquamet L; Loiodice M; Rochu D; Masson P; Nachon F
    J Enzyme Inhib Med Chem; 2009 Aug; 24(4):1045-55. PubMed ID: 19548794
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.