These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 20124006)

  • 1. Inhibition of HIV-1 replication by a bis-thiadiazolbenzene-1,2-diamine that chelates zinc ions from retroviral nucleocapsid zinc fingers.
    Pannecouque C; Szafarowicz B; Volkova N; Bakulev V; Dehaen W; Mély Y; Daelemans D
    Antimicrob Agents Chemother; 2010 Apr; 54(4):1461-8. PubMed ID: 20124006
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Anti-HIV agents that selectively target retroviral nucleocapsid protein zinc fingers without affecting cellular zinc finger proteins.
    Huang M; Maynard A; Turpin JA; Graham L; Janini GM; Covell DG; Rice WG
    J Med Chem; 1998 Apr; 41(9):1371-81. PubMed ID: 9554870
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of multiple phases of human immunodeficiency virus type 1 replication by a dithiane compound that attacks the conserved zinc fingers of retroviral nucleocapsid proteins.
    Rice WG; Baker DC; Schaeffer CA; Graham L; Bu M; Terpening S; Clanton D; Schultz R; Bader JP; Buckheit RW; Field L; Singh PK; Turpin JA
    Antimicrob Agents Chemother; 1997 Feb; 41(2):419-26. PubMed ID: 9021201
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Azodicarbonamide inhibits HIV-1 replication by targeting the nucleocapsid protein.
    Rice WG; Turpin JA; Huang M; Clanton D; Buckheit RW; Covell DG; Wallqvist A; McDonnell NB; DeGuzman RN; Summers MF; Zalkow L; Bader JP; Haugwitz RD; Sausville EA
    Nat Med; 1997 Mar; 3(3):341-5. PubMed ID: 9055865
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions.
    Vercruysse T; Basta B; Dehaen W; Humbert N; Balzarini J; Debaene F; Sanglier-Cianférani S; Pannecouque C; Mély Y; Daelemans D
    Retrovirology; 2012 Nov; 9():95. PubMed ID: 23146561
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The human immunodeficiency virus type 1 (HIV-1) nucleocapsid protein zinc ejection activity of disulfide benzamides and benzisothiazolones: correlation with anti-HIV and virucidal activities.
    Tummino PJ; Harvey PJ; McQuade T; Domagala J; Gogliotti R; Sanchez J; Song Y; Hupe D
    Antimicrob Agents Chemother; 1997 Feb; 41(2):394-400. PubMed ID: 9021197
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mimic of HIV-1 nucleocapsid protein impairs reverse transcription and displays antiviral activity.
    Druillennec S; Dong CZ; Escaich S; Gresh N; Bousseau A; Roques BP; Fournié-Zaluski MC
    Proc Natl Acad Sci U S A; 1999 Apr; 96(9):4886-91. PubMed ID: 10220388
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of HIV-1 nucleocapsid protein P7 by pyridinioalkanoyl thioesters. Characterization of reaction products and proposed mechanism of action.
    Basrur V; Song Y; Mazur SJ; Higashimoto Y; Turpin JA; Rice WG; Inman JK; Appella E
    J Biol Chem; 2000 May; 275(20):14890-7. PubMed ID: 10809733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 1H NMR structure and biological studies of the His23-->Cys mutant nucleocapsid protein of HIV-1 indicate that the conformation of the first zinc finger is critical for virus infectivity.
    Déméné H; Dong CZ; Ottmann M; Rouyez MC; Jullian N; Morellet N; Mely Y; Darlix JL; Fournié-Zaluski MC; Saragosti S
    Biochemistry; 1994 Oct; 33(39):11707-16. PubMed ID: 7918387
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of Natural Compounds in Licorice and Turmeric with HIV-NCp7 Zinc Finger Domain: Potential Relevance to the Mechanism of Antiviral Activity.
    Wang R; Wei Y; Wang M; Yan P; Jiang H; Du Z
    Molecules; 2021 Jun; 26(12):. PubMed ID: 34200973
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological properties of novel pyridinioalkanoyl thiolesters (PATE) as anti-HIV-1 agents that target the viral nucleocapsid protein zinc fingers.
    Turpin JA; Song Y; Inman JK; Huang M; Wallqvist A; Maynard A; Covell DG; Rice WG; Appella E
    J Med Chem; 1999 Jan; 42(1):67-86. PubMed ID: 9888834
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of intermediates in the oxidation of zinc fingers in human immunodeficiency virus type 1 nucleocapsid protein P7.
    Hathout Y; Fabris D; Han MS; Sowder RC; Henderson LE; Fenselau C
    Drug Metab Dispos; 1996 Dec; 24(12):1395-400. PubMed ID: 8971148
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the zinc finger domain encompassing residues 13-51 of the nucleocapsid protein from simian immunodeficiency virus.
    Morellet N; Meudal H; Bouaziz S; Roques BP
    Biochem J; 2006 Feb; 393(Pt 3):725-32. PubMed ID: 16229684
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification by high throughput screening of small compounds inhibiting the nucleic acid destabilization activity of the HIV-1 nucleocapsid protein.
    Shvadchak V; Sanglier S; Rocle S; Villa P; Haiech J; Hibert M; Van Dorsselaer A; Mély Y; de Rocquigny H
    Biochimie; 2009 Jul; 91(7):916-23. PubMed ID: 19401213
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thermal stressed human immunodeficiency virus type 1 nucleocapsid protein NCp7 maintains nucleic acid-binding activity.
    Guo C; Han J; Liu Y; Wang J; Wang Y
    Biochem Biophys Res Commun; 2020 Jun; 526(3):721-727. PubMed ID: 32253032
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies on the mechanism of inactivation of the HIV-1 nucleocapsid protein NCp7 with 2-mercaptobenzamide thioesters.
    Jenkins LM; Byrd JC; Hara T; Srivastava P; Mazur SJ; Stahl SJ; Inman JK; Appella E; Omichinski JG; Legault P
    J Med Chem; 2005 Apr; 48(8):2847-58. PubMed ID: 15828823
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Binding properties of the human immunodeficiency virus type 1 nucleocapsid protein p7 to a model RNA: elucidation of the structural determinants for function.
    Urbaneja MA; Kane BP; Johnson DG; Gorelick RJ; Henderson LE; Casas-Finet JR
    J Mol Biol; 1999 Mar; 287(1):59-75. PubMed ID: 10074407
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural determinants of HIV-1 nucleocapsid protein for cTAR DNA binding and destabilization, and correlation with inhibition of self-primed DNA synthesis.
    Beltz H; Clauss C; Piémont E; Ficheux D; Gorelick RJ; Roques B; Gabus C; Darlix JL; de Rocquigny H; Mély Y
    J Mol Biol; 2005 May; 348(5):1113-26. PubMed ID: 15854648
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preclinical evaluation of a zinc finger inhibitor targeting lentivirus nucleocapsid protein in SIV-infected monkeys.
    Schito ML; Soloff AC; Slovitz D; Trichel A; Inman JK; Appella E; Turpin JA; Barratt-Boyes SM
    Curr HIV Res; 2006 Jul; 4(3):379-86. PubMed ID: 16842089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Experimental determination and calculations of redox potential descriptors of compounds directed against retroviral zinc fingers: Implications for rational drug design.
    Topol IA; McGrath C; Chertova E; Dasenbrock C; Lacourse WR; Eissenstat MA; Burt SK; Henderson LE; Casas-Finet JR
    Protein Sci; 2001 Jul; 10(7):1434-45. PubMed ID: 11420445
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.