BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

342 related articles for article (PubMed ID: 20132940)

  • 1. A high throughput metabolic stability screening workflow with automated assessment of data quality in pharmaceutical industry.
    Xu R; Manuel M; Cramlett J; Kassel DB
    J Chromatogr A; 2010 Mar; 1217(10):1616-25. PubMed ID: 20132940
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A high-throughput bioanalytical platform using automated infusion for tandem mass spectrometric method optimization and its application in a metabolic stability screen.
    Kieltyka K; Zhang J; Li S; Vath M; Baglieri C; Ferraro C; Zvyaga TA; Drexler DM; Weller HN; Shou WZ
    Rapid Commun Mass Spectrom; 2009 Jun; 23(11):1579-91. PubMed ID: 19399765
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of stable isotope labeled probes to facilitate liquid chromatography/mass spectrometry based high-throughput screening of time-dependent CYP inhibitors.
    Dasgupta M; Tang W; Caldwell GW; Yan Z
    Rapid Commun Mass Spectrom; 2010 Aug; 24(15):2177-85. PubMed ID: 20583325
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.
    Youdim KA; Saunders KC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(17-18):1326-36. PubMed ID: 20207203
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Application of a rapid and integrated analysis system (RIAS) as a high-throughput processing tool for in vitro ADME samples by liquid chromatography/tandem mass spectrometry.
    Luippold AH; Arnhold T; Jörg W; Krüger B; Süssmuth RD
    J Biomol Screen; 2011 Mar; 16(3):370-7. PubMed ID: 21335598
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Addressing the analytical throughput challenges in ADME screening using rapid ultra-performance liquid chromatography/tandem mass spectrometry methodologies.
    Plumb RS; Potts WB; Rainville PD; Alden PG; Shave DH; Baynham G; Mazzeo JR
    Rapid Commun Mass Spectrom; 2008 Jul; 22(14):2139-52. PubMed ID: 18543375
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mass spectrometric techniques for label-free high-throughput screening in drug discovery.
    Roddy TP; Horvath CR; Stout SJ; Kenney KL; Ho PI; Zhang JH; Vickers C; Kaushik V; Hubbard B; Wang YK
    Anal Chem; 2007 Nov; 79(21):8207-13. PubMed ID: 17902631
    [TBL] [Abstract][Full Text] [Related]  

  • 8. High-throughput, 384-well, LC-MS/MS CYP inhibition assay using automation, cassette-analysis technique, and streamlined data analysis.
    Halladay JS; Delarosa EM; Tran D; Wang L; Wong S; Khojasteh SC
    Drug Metab Lett; 2011 Aug; 5(3):220-30. PubMed ID: 21867481
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Optimization of a higher throughput microsomal stability screening assay for profiling drug discovery candidates.
    Di L; Kerns EH; Hong Y; Kleintop TA; McConnell OJ; Huryn DM
    J Biomol Screen; 2003 Aug; 8(4):453-62. PubMed ID: 14567798
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Automatic mass spectrometry method development for drug discovery: application in metabolic stability assays.
    Chovan LE; Black-Schaefer C; Dandliker PJ; Lau YY
    Rapid Commun Mass Spectrom; 2004; 18(24):3105-12. PubMed ID: 15565734
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro ADME profiling using high-throughput rapidfire mass spectrometry: cytochrome p450 inhibition and metabolic stability assays.
    Wu X; Wang J; Tan L; Bui J; Gjerstad E; McMillan K; Zhang W
    J Biomol Screen; 2012 Jul; 17(6):761-72. PubMed ID: 22460176
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel approach to perform metabolite screening during the quantitative LC-MS/MS analyses of in vitro metabolic stability samples using a hybrid triple-quadrupole linear ion trap mass spectrometer.
    Shou WZ; Magis L; Li AC; Naidong W; Bryant MS
    J Mass Spectrom; 2005 Oct; 40(10):1347-56. PubMed ID: 16206149
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolic stability screen for drug discovery using cassette analysis and column switching.
    Halladay JS; Wong S; Jaffer SM; Sinhababu AK; Khojasteh-Bakht SC
    Drug Metab Lett; 2007 Jan; 1(1):67-72. PubMed ID: 19356021
    [TBL] [Abstract][Full Text] [Related]  

  • 14. High-throughput quantification for a drug mixture in rat plasma-a comparison of Ultra Performance liquid chromatography/tandem mass spectrometry with high-performance liquid chromatography/tandem mass spectrometry.
    Yu K; Little D; Plumb R; Smith B
    Rapid Commun Mass Spectrom; 2006; 20(4):544-52. PubMed ID: 16419023
    [TBL] [Abstract][Full Text] [Related]  

  • 15. High-throughput cytochrome p450 inhibition assays by ultrafast gradient liquid chromatography with tandem mass spectrometry using monolithic columns.
    Peng SX; Barbone AG; Ritchie DM
    Rapid Commun Mass Spectrom; 2003; 17(6):509-18. PubMed ID: 12621611
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increasing high-throughput discovery bioanalysis using automated selected reaction monitoring compound optimization, ultra-high-pressure liquid chromatography, and single-step sample preparation workflows.
    Smalley J; Xin B; Olah TV
    Rapid Commun Mass Spectrom; 2009 Nov; 23(21):3457-64. PubMed ID: 19813283
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evaluation of laser diode thermal desorption (LDTD) coupled with tandem mass spectrometry (MS/MS) for support of in vitro drug discovery assays: increasing scope, robustness and throughput of the LDTD technique for use with chemically diverse compound libraries.
    Beattie I; Smith A; Weston DJ; White P; Szwandt S; Sealey L
    J Pharm Biomed Anal; 2012 Feb; 59():18-28. PubMed ID: 22071442
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ultra-performance liquid chromatography coupled to time-of-flight mass spectrometry for robust, high-throughput quantitative analysis of an automated metabolic stability assay, with simultaneous determination of metabolic data.
    O'Connor D; Mortishire-Smith R; Morrison D; Davies A; Dominguez M
    Rapid Commun Mass Spectrom; 2006; 20(5):851-7. PubMed ID: 16470510
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Supercritical fluid chromatography/tandem mass spectrometric method for analysis of pharmaceutical compounds in metabolic stability samples.
    Hsieh Y; Favreau L; Schwerdt J; Cheng KC
    J Pharm Biomed Anal; 2006 Feb; 40(3):799-804. PubMed ID: 16095863
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High throughput metabolic stability screen for lead optimization in drug discovery.
    Tong XS; Xu S; Zheng S; Pivnichny JV; Martin J; Dufresne C
    J Chromatogr B Analyt Technol Biomed Life Sci; 2006 Apr; 833(2):165-73. PubMed ID: 16504609
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.