180 related articles for article (PubMed ID: 20133694)
1. Allosteric gating of Son of sevenless activity by the histone domain.
Yadav KK; Bar-Sagi D
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3436-40. PubMed ID: 20133694
[TBL] [Abstract][Full Text] [Related]
2. Role of the histone domain in the autoinhibition and activation of the Ras activator Son of Sevenless.
Gureasko J; Kuchment O; Makino DL; Sondermann H; Bar-Sagi D; Kuriyan J
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3430-5. PubMed ID: 20133692
[TBL] [Abstract][Full Text] [Related]
3. A Ras-induced conformational switch in the Ras activator Son of sevenless.
Freedman TS; Sondermann H; Friedland GD; Kortemme T; Bar-Sagi D; Marqusee S; Kuriyan J
Proc Natl Acad Sci U S A; 2006 Nov; 103(45):16692-7. PubMed ID: 17075039
[TBL] [Abstract][Full Text] [Related]
4. Phospholipase D2-generated phosphatidic acid couples EGFR stimulation to Ras activation by Sos.
Zhao C; Du G; Skowronek K; Frohman MA; Bar-Sagi D
Nat Cell Biol; 2007 Jun; 9(6):706-12. PubMed ID: 17486115
[TBL] [Abstract][Full Text] [Related]
5. Membrane-dependent signal integration by the Ras activator Son of sevenless.
Gureasko J; Galush WJ; Boykevisch S; Sondermann H; Bar-Sagi D; Groves JT; Kuriyan J
Nat Struct Mol Biol; 2008 May; 15(5):452-61. PubMed ID: 18454158
[TBL] [Abstract][Full Text] [Related]
6. Mechanism of SOS PR-domain autoinhibition revealed by single-molecule assays on native protein from lysate.
Lee YK; Low-Nam ST; Chung JK; Hansen SD; Lam HYM; Alvarez S; Groves JT
Nat Commun; 2017 Apr; 8():15061. PubMed ID: 28452363
[TBL] [Abstract][Full Text] [Related]
7. Structural analysis of autoinhibition in the Ras activator Son of sevenless.
Sondermann H; Soisson SM; Boykevisch S; Yang SS; Bar-Sagi D; Kuriyan J
Cell; 2004 Oct; 119(3):393-405. PubMed ID: 15507210
[TBL] [Abstract][Full Text] [Related]
8. Computational docking and solution x-ray scattering predict a membrane-interacting role for the histone domain of the Ras activator son of sevenless.
Sondermann H; Nagar B; Bar-Sagi D; Kuriyan J
Proc Natl Acad Sci U S A; 2005 Nov; 102(46):16632-7. PubMed ID: 16267129
[TBL] [Abstract][Full Text] [Related]
9. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes.
Roose JP; Mollenauer M; Ho M; Kurosaki T; Weiss A
Mol Cell Biol; 2007 Apr; 27(7):2732-45. PubMed ID: 17283063
[TBL] [Abstract][Full Text] [Related]
10. An activating mutation in sos-1 identifies its Dbl domain as a critical inhibitor of the epidermal growth factor receptor pathway during Caenorhabditis elegans vulval development.
Modzelewska K; Elgort MG; Huang J; Jongeward G; Lauritzen A; Yoon CH; Sternberg PW; Moghal N
Mol Cell Biol; 2007 May; 27(10):3695-707. PubMed ID: 17339331
[TBL] [Abstract][Full Text] [Related]
11. Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange.
Burns MC; Sun Q; Daniels RN; Camper D; Kennedy JP; Phan J; Olejniczak ET; Lee T; Waterson AG; Rossanese OW; Fesik SW
Proc Natl Acad Sci U S A; 2014 Mar; 111(9):3401-6. PubMed ID: 24550516
[TBL] [Abstract][Full Text] [Related]
12. Tandem histone folds in the structure of the N-terminal segment of the ras activator Son of Sevenless.
Sondermann H; Soisson SM; Bar-Sagi D; Kuriyan J
Structure; 2003 Dec; 11(12):1583-93. PubMed ID: 14656442
[TBL] [Abstract][Full Text] [Related]
13. Differences in flexibility underlie functional differences in the Ras activators son of sevenless and Ras guanine nucleotide releasing factor 1.
Freedman TS; Sondermann H; Kuchment O; Friedland GD; Kortemme T; Kuriyan J
Structure; 2009 Jan; 17(1):41-53. PubMed ID: 19141281
[TBL] [Abstract][Full Text] [Related]
14. Monitoring Ras Interactions with the Nucleotide Exchange Factor Son of Sevenless (Sos) Using Site-specific NMR Reporter Signals and Intrinsic Fluorescence.
Vo U; Vajpai N; Flavell L; Bobby R; Breeze AL; Embrey KJ; Golovanov AP
J Biol Chem; 2016 Jan; 291(4):1703-1718. PubMed ID: 26565026
[TBL] [Abstract][Full Text] [Related]
15. New insights into the mechanisms of SOS activation.
Quilliam LA
Sci STKE; 2007 Nov; 2007(414):pe67. PubMed ID: 18042941
[TBL] [Abstract][Full Text] [Related]
16. Understanding SOS (Son of Sevenless).
Pierre S; Bats AS; Coumoul X
Biochem Pharmacol; 2011 Nov; 82(9):1049-56. PubMed ID: 21787760
[TBL] [Abstract][Full Text] [Related]
17. Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles.
Liao TJ; Jang H; Fushman D; Nussinov R
Biophys J; 2018 Aug; 115(4):629-641. PubMed ID: 30097175
[TBL] [Abstract][Full Text] [Related]
18. Regulation of Sos activity by intramolecular interactions.
Corbalan-Garcia S; Margarit SM; Galron D; Yang SS; Bar-Sagi D
Mol Cell Biol; 1998 Feb; 18(2):880-6. PubMed ID: 9447984
[TBL] [Abstract][Full Text] [Related]
19. Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods.
Sarkar D; Olejniczak ET; Phan J; Coker JA; Sai J; Arnold A; Beesetty Y; Waterson AG; Fesik SW
J Med Chem; 2020 Aug; 63(15):8325-8337. PubMed ID: 32673492
[TBL] [Abstract][Full Text] [Related]
20. High-throughput screening identifies small molecules that bind to the RAS:SOS:RAS complex and perturb RAS signaling.
Burns MC; Howes JE; Sun Q; Little AJ; Camper DV; Abbott JR; Phan J; Lee T; Waterson AG; Rossanese OW; Fesik SW
Anal Biochem; 2018 May; 548():44-52. PubMed ID: 29444450
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
