BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

285 related articles for article (PubMed ID: 20133707)

  • 1. Defining the ATM-mediated barrier to tumorigenesis in somatic mammary cells following ErbB2 activation.
    Reddy JP; Peddibhotla S; Bu W; Zhao J; Haricharan S; Du YC; Podsypanina K; Rosen JM; Donehower LA; Li Y
    Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3728-33. PubMed ID: 20133707
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Myc-evoked DNA damage response accounts for treatment resistance in primary lymphomas in vivo.
    Reimann M; Loddenkemper C; Rudolph C; Schildhauer I; Teichmann B; Stein H; Schlegelberger B; Dörken B; Schmitt CA
    Blood; 2007 Oct; 110(8):2996-3004. PubMed ID: 17562874
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
    Sluss HK; Gannon H; Coles AH; Shen Q; Eischen CM; Jones SN
    Mol Cancer Res; 2010 Feb; 8(2):216-22. PubMed ID: 20145032
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ataxia telangiectasia mutated (ATM) inhibition transforms human mammary gland epithelial cells.
    Mandriota SJ; Buser R; Lesne L; Stouder C; Favaudon V; Maechler P; Béna F; Clément V; Rüegg C; Montesano R; Sappino AP
    J Biol Chem; 2010 Apr; 285(17):13092-106. PubMed ID: 20177072
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of the ATM-Snail pathway promotes breast cancer metastasis.
    Sun M; Guo X; Qian X; Wang H; Yang C; Brinkman KL; Serrano-Gonzalez M; Jope RS; Zhou B; Engler DA; Zhan M; Wong ST; Fu L; Xu B
    J Mol Cell Biol; 2012 Oct; 4(5):304-15. PubMed ID: 22923499
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer.
    Menendez JA; Cufí S; Oliveras-Ferraros C; Martin-Castillo B; Joven J; Vellon L; Vazquez-Martin A
    Aging (Albany NY); 2011 Nov; 3(11):1063-77. PubMed ID: 22170748
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.
    Zhan H; Suzuki T; Aizawa K; Miyagawa K; Nagai R
    J Biol Chem; 2010 Sep; 285(38):29662-70. PubMed ID: 20639198
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus.
    E X; Pickering MT; Debatis M; Castillo J; Lagadinos A; Wang S; Lu S; Kowalik TF
    PLoS Pathog; 2011 May; 7(5):e1001342. PubMed ID: 21589897
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.
    Korwek Z; Sewastianik T; Bielak-Zmijewska A; Mosieniak G; Alster O; Moreno-Villanueva M; Burkle A; Sikora E
    DNA Repair (Amst); 2012 Nov; 11(11):864-73. PubMed ID: 23058634
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The DNA damage signalling kinase ATM is aberrantly reduced or lost in BRCA1/BRCA2-deficient and ER/PR/ERBB2-triple-negative breast cancer.
    Tommiska J; Bartkova J; Heinonen M; Hautala L; Kilpivaara O; Eerola H; Aittomäki K; Hofstetter B; Lukas J; von Smitten K; Blomqvist C; Ristimäki A; Heikkilä P; Bartek J; Nevanlinna H
    Oncogene; 2008 Apr; 27(17):2501-6. PubMed ID: 17982490
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oncogenes and the DNA damage response: Myc and E2F1 engage the ATM signaling pathway to activate p53 and induce apoptosis.
    Hong S; Pusapati RV; Powers JT; Johnson DG
    Cell Cycle; 2006 Apr; 5(8):801-3. PubMed ID: 16582589
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.
    Song L; Lin C; Wu Z; Gong H; Zeng Y; Wu J; Li M; Li J
    PLoS One; 2011; 6(9):e25454. PubMed ID: 21980462
    [TBL] [Abstract][Full Text] [Related]  

  • 13. ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.
    Cao L; Kim S; Xiao C; Wang RH; Coumoul X; Wang X; Li WM; Xu XL; De Soto JA; Takai H; Mai S; Elledge SJ; Motoyama N; Deng CX
    EMBO J; 2006 May; 25(10):2167-77. PubMed ID: 16675955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA; Cragg MS; Davidson SM; McCormick J; Barry S; Lawrence KM; Knight RA; Hubank M; Chen PL; Latchman DS; Stephanou A
    J Cell Sci; 2005 Apr; 118(Pt 8):1629-39. PubMed ID: 15784679
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
    Teoh N; Pyakurel P; Dan YY; Swisshelm K; Hou J; Mitchell C; Fausto N; Gu Y; Farrell G
    Gastroenterology; 2010 Mar; 138(3):1155-65.e1-2. PubMed ID: 19919837
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization.
    Di Micco R; Cicalese A; Fumagalli M; Dobreva M; Verrecchia A; Pelicci PG; di Fagagna Fd
    Cell Cycle; 2008 Nov; 7(22):3601-6. PubMed ID: 19001874
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis.
    Maclean KH; Dorsey FC; Cleveland JL; Kastan MB
    J Clin Invest; 2008 Jan; 118(1):79-88. PubMed ID: 18097482
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
    Rodier F; Coppé JP; Patil CK; Hoeijmakers WA; Muñoz DP; Raza SR; Freund A; Campeau E; Davalos AR; Campisi J
    Nat Cell Biol; 2009 Aug; 11(8):973-9. PubMed ID: 19597488
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATM localization and gene expression in the adult mouse eye.
    Leemput J; Masson C; Bigot K; Errachid A; Dansault A; Provost A; Gadin S; Aoufouchi S; Menasche M; Abitbol M
    Mol Vis; 2009; 15():393-416. PubMed ID: 19234633
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis.
    Yamamoto K; Nihrane A; Aglipay J; Sironi J; Arkin S; Lipton JM; Ouchi T; Liu JM
    Mol Med; 2008; 14(3-4):167-74. PubMed ID: 18224251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.