489 related articles for article (PubMed ID: 20133899)
21. Electrophysiological and fluorescence microscopy studies with HERG channel/EGFP fusion proteins.
Claassen S; Schwarzer S; Ludwig J; Zünkler BJ
J Membr Biol; 2008 Mar; 222(1):31-41. PubMed ID: 18414922
[TBL] [Abstract][Full Text] [Related]
22. Inhibition of the HERG channel by droperidol depends on channel gating and involves the S6 residue F656.
Luo T; Luo A; Liu M; Liu X
Anesth Analg; 2008 Apr; 106(4):1161-70, table of contents. PubMed ID: 18349188
[TBL] [Abstract][Full Text] [Related]
23. Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656.
Park SJ; Kim KS; Kim EJ
J Appl Toxicol; 2008 Mar; 28(2):104-11. PubMed ID: 17516459
[TBL] [Abstract][Full Text] [Related]
24. [HERG K+ channel, the target of anti-arrhythmias drugs].
Guan FY; Yang SJ
Yao Xue Xue Bao; 2007 Jul; 42(7):687-91. PubMed ID: 17882949
[TBL] [Abstract][Full Text] [Related]
25. 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD-307243) causes instantaneous current through human ether-a-go-go-related gene potassium channels.
Gordon E; Lozinskaya IM; Lin Z; Semus SF; Blaney FE; Willette RN; Xu X
Mol Pharmacol; 2008 Mar; 73(3):639-51. PubMed ID: 18042732
[TBL] [Abstract][Full Text] [Related]
26. HERG channel (dys)function revealed by dynamic action potential clamp technique.
Berecki G; Zegers JG; Verkerk AO; Bhuiyan ZA; de Jonge B; Veldkamp MW; Wilders R; van Ginneken AC
Biophys J; 2005 Jan; 88(1):566-78. PubMed ID: 15475579
[TBL] [Abstract][Full Text] [Related]
27. Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels.
Mullins FM; Stepanovic SZ; Gillani NB; George AL; Balser JR
J Physiol; 2004 Aug; 558(Pt 3):729-44. PubMed ID: 15169846
[TBL] [Abstract][Full Text] [Related]
28. Pharmacological inhibition of the hERG potassium channel is modulated by extracellular but not intracellular acidosis.
DU CY; El Harchi A; Zhang YH; Orchard CH; Hancox JC
J Cardiovasc Electrophysiol; 2011 Oct; 22(10):1163-70. PubMed ID: 21489024
[TBL] [Abstract][Full Text] [Related]
29. Modulation of I(Kr) inactivation by mutation N588K in KCNH2: a link to arrhythmogenesis in short QT syndrome.
Cordeiro JM; Brugada R; Wu YS; Hong K; Dumaine R
Cardiovasc Res; 2005 Aug; 67(3):498-509. PubMed ID: 16039272
[TBL] [Abstract][Full Text] [Related]
30. hERG K(+) channels: structure, function, and clinical significance.
Vandenberg JI; Perry MD; Perrin MJ; Mann SA; Ke Y; Hill AP
Physiol Rev; 2012 Jul; 92(3):1393-478. PubMed ID: 22988594
[TBL] [Abstract][Full Text] [Related]
31. Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.
Rajamani S; Eckhardt LL; Valdivia CR; Klemens CA; Gillman BM; Anderson CL; Holzem KM; Delisle BP; Anson BD; Makielski JC; January CT
Br J Pharmacol; 2006 Nov; 149(5):481-9. PubMed ID: 16967046
[TBL] [Abstract][Full Text] [Related]
32. RNA interference targeting E637K mutation rescues hERG channel currents and restores its kinetic properties.
Lu X; Yang X; Huang X; Huang C; Sun HH; Jin L; Xu W; Mao H; Guo J; Zhou J; Lian J
Heart Rhythm; 2013 Jan; 10(1):128-36. PubMed ID: 23022675
[TBL] [Abstract][Full Text] [Related]
33. Proton block of the pore underlies the inhibition of hERG cardiac K+ channels during acidosis.
Van Slyke AC; Cheng YM; Mafi P; Allard CR; Hull CM; Shi YP; Claydon TW
Am J Physiol Cell Physiol; 2012 Jun; 302(12):C1797-806. PubMed ID: 22517356
[TBL] [Abstract][Full Text] [Related]
34. Downregulation of the HERG (KCNH2) K(+) channel by ceramide: evidence for ubiquitin-mediated lysosomal degradation.
Chapman H; Ramström C; Korhonen L; Laine M; Wann KT; Lindholm D; Pasternack M; Törnquist K
J Cell Sci; 2005 Nov; 118(Pt 22):5325-34. PubMed ID: 16263765
[TBL] [Abstract][Full Text] [Related]
35. The cardiac hERG/IKr potassium channel as pharmacological target: structure, function, regulation, and clinical applications.
Thomas D; Karle CA; Kiehn J
Curr Pharm Des; 2006; 12(18):2271-83. PubMed ID: 16787254
[TBL] [Abstract][Full Text] [Related]
36. Febrile temperature facilitates hERG/IKr degradation through an altered K(+) dependence.
Zhao Y; Wang T; Guo J; Yang T; Li W; Koichopolos J; Lamothe SM; Kang Y; Ma A; Zhang S
Heart Rhythm; 2016 Oct; 13(10):2004-11. PubMed ID: 27321242
[TBL] [Abstract][Full Text] [Related]
37. Clemastine, a conventional antihistamine, is a high potency inhibitor of the HERG K+ channel.
Ridley JM; Milnes JT; Hancox JC; Witchel HJ
J Mol Cell Cardiol; 2006 Jan; 40(1):107-18. PubMed ID: 16288909
[TBL] [Abstract][Full Text] [Related]
38. The evolutionarily conserved residue A653 plays a key role in HERG channel closing.
Stepanovic SZ; Potet F; Petersen CI; Smith JA; Meiler J; Balser JR; Kupershmidt S
J Physiol; 2009 Jun; 587(Pt 11):2555-66. PubMed ID: 19406877
[TBL] [Abstract][Full Text] [Related]
39. Comparative effects of the short QT N588K mutation at 37 degrees C on hERG K+ channel current during ventricular, Purkinje fibre and atrial action potentials: an action potential clamp study.
McPate MJ; Zhang H; Adeniran I; Cordeiro JM; Witchel HJ; Hancox JC
J Physiol Pharmacol; 2009 Mar; 60(1):23-41. PubMed ID: 19439805
[TBL] [Abstract][Full Text] [Related]
40. Chimeric hERG channels containing a tetramerization domain are functional and stable.
Hausammann GJ; Grütter MG
Biochemistry; 2013 Dec; 52(51):9237-45. PubMed ID: 24325597
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
